Important: This destination may have COVID-19 travel restrictions in place, including specific restrictions for lodging. Check any national, local, and health advisories for this destination before you book.

Find Hotels in Louisiana

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Louisiana hotels and places to stay

River's Edge Motel
2 out of 5
201 Mansion St, Louisiana, MO
Free CancellationReserve now, pay when you stay
The price is $72 per night
3.68 mi from city center
4.4/5Wonderful! (112 reviews)

"I liked the location. Close to where I was training and overlooked the Mississippi River."…"

Reviewed on Feb 3, 2020

River's Edge Motel
Garth Woodside Mansion Bed and Breakfast
3.5 out of 5
11069 New London Gravel Rd, Hannibal, MO
The price is $209 per night
21.36 mi from city center
4.8/5Exceptional! (8 reviews)
FABULOUS HOME-LIKE ATMOSPHERE

"Walking through the door opens to warm smile and cozy magnificence throughout this mansion, a true peaceful experience from check-in to check-out; will be back.....THANK YOU!"…"

Reviewed on Jan 1, 2020

Garth Woodside Mansion Bed and Breakfast
Log Home/lodge Getaway
Get Rates
26.81 mi from city center
4.8/5Exceptional! (6 reviews)
Great family time!!

"This property is amazing, it is large and open yet feels warm n cozy. Great family time playing games around the table, Cooking together, and just reconnecting. Yet plenty of room for our girls to enjoy their own time and space as well. We had a great time and very easy communicating with owner!"…"

Reviewed on May 13, 2020

Log Home/lodge Getaway
Country Hearth Inn Hannibal
2 out of 5
500 Mark Twain Ave, Hannibal, MO
Free CancellationReserve now, pay when you stay
The price is $50 per night
22.12 mi from city center
2.3/5 (128 reviews)

"I liked that the room had 3 beds to accommodate the size of our family, but the sheets were stained and there was a musty smell to the room."…"

Reviewed on Oct 20, 2019

Country Hearth Inn Hannibal
West Central Lodging
2.5 out of 5
20545 County Hwy 11, Pittsfield, IL
Free Cancellation
The price is $80 per night
17.97 mi from city center
West Central Lodging
Motel 6 Hannibal MO
2 out of 5
123 Huckleberry Heights Dr, Hannibal, MO
Free Cancellation
The price is $46 per night
22.26 mi from city center
3.4/5 (441 reviews)
Splash

"Stayed here because they have a nice pool. The grandsons had a great time. Will stay again."…"

Reviewed on Feb 24, 2020

Motel 6 Hannibal MO
Best Western On The River
2.5 out of 5
401 North 3rd Street, Hannibal, MO
Free CancellationReserve now, pay when you stay
The price is $87 per night
21.95 mi from city center
4.3/5Excellent! (839 reviews)

"Great location. Staff was very friendly and informative. Nice motel and the room was great."…"

Reviewed on Apr 18, 2020

Best Western On The River
Super 8 by Wyndham Hannibal
2 out of 5
120 Huckleberry Heights Dr, Hannibal, MO
Free CancellationReserve now, pay when you stay
The price is $54 per night
22.26 mi from city center
3.5/5Good! (688 reviews)

"Me and the Wife just wanted to get away for the weekend. Staff was super friendly, Room was nice. Close to what we wanted to do"…"

Reviewed on Feb 27, 2020

Super 8 by Wyndham Hannibal
Super 8 by Wyndham Bowling Green
2 out of 5
1216 E Champ Clark Dr, Bowling Green, MO
Free CancellationReserve now, pay when you stay
The price is $89 per night
8.81 mi from city center
4/5Very Good! (204 reviews)

"Close to gas, food and stores and only 22 minutes from our event we were attending."…"

Reviewed on May 14, 2020

Super 8 by Wyndham Bowling Green
Main Street Bed & Breakfast
3.5 out of 5
Main at Center Street, Hannibal, MO
Free CancellationReserve now, pay when you stay
The price is $125 per night
21.79 mi from city center
4.3/5Excellent! (69 reviews)

"Would have enjoyed a full breakfast"…"

Reviewed on Nov 19, 2019

Main Street Bed & Breakfast
Can't find the property you want?
See all available properties in Louisiana
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Visiting Louisiana

Visitors to Louisiana are sure to enjoy the riverfront. This city also attracts tourists with its welcoming and relaxing setting.

  • You'll find 26 Expedia hotels and other accommodations in the larger area of Hannibal
  • The closest major airport is in Quincy, IL (UIN-Quincy Regional-Baldwin Field), 33.6 mi (54 km) from the city center

Sightseeing and Staying in Louisiana

Places to visit in the larger region include Clarksville State Game Refuge, Clarksville Riverfront Park, and Ramsey Creek Church. Additionally, you'll find Mark Twain Cave in the area.

This is a top rated accommodation based on Expedia user reviews:

  • River's Edge Motel - Amenities at this 2-star motel include free parking and a 24-hour front desk. It's a favorite with Expedia travelers for its helpful staff and clean rooms.

Dressing for Louisiana

  • Between January and March, you can expect average temperatures of 58°F during the day and 17°F at night
  • From April to June, the average during the day is 86°F, while the average at night is 37°F
  • July through September has daytime averages of 87°F with nighttime averages of 48°F
  • In October-December, you can expect daytime averages of 73°F and nighttime averages of 18°F
  • Average annual rainfall for Louisiana is 41.46 inches
  • Usually July and August are the hottest months with an average of 86°F, whereas January and December are often coldest, averaging 20°F

Frequently asked questions

Where is the best place to stay in Louisiana?
River’s Edge Motel is one of the top choices for your stay based on our traveler data. This property offers free WiFi and free parking. Other good options for your stay in the area are Holiday Inn Express And Suites Hannibal - Medical Center and Quality Inn & Suites Hannibal.
If I need to cancel my hotel reservation in Louisiana, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if cancelled prior to the accommodation’s cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that’s non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Put your dates in and click on “Search”, then use the “free cancellation” filter to review the best deals in Louisiana.
Where can I learn more about changing or cancelling my trip to Louisiana?
To access more information about picking new dates or cancelling your trip to Louisiana, go to https://www.expedia.com/service/.
What's the best hotel to stay near The Eagle's Nest Winery?
River’s Edge Motel is one of the top choices for your stay based on our traveler data, and this property offers free WiFi and free parking. It’s located just a short 0.4 mi (0.6 km) from The Eagle’s Nest Winery. Other good choices in the area include Super 8 by Wyndham Bowling Green and Knights Inn Pittsfield.
What are some hotels with pools in Louisiana?
Holiday Inn Express And Suites Hannibal - Medical Center: Offers free buffet breakfast, an indoor pool, and free parking. Quality Inn & Suites Hannibal and Sleep Inn & Suites are two additional hotels with an onsite pool.
What's the best accommodation near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It’s located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
What is staying in Louisiana like?
Visitors to Louisiana are sure to enjoy the riverfront. This city also attracts tourists with its welcoming and relaxing setting. There are 32 hotels and other accommodations in the surrounding area.
What should I do while I'm visiting Louisiana?
Places to visit in the larger region include Mark Twain Cave, Clarksville State Game Refuge, and Clarksville Riverfront Park. Additionally, you’ll find Ramsey Creek Church.
What's the seasonal weather like in Louisiana?
The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and December with an average of 32°F. Average annual rainfall for Louisiana is 41 inches.

Recent reviews of Louisiana hotels

More trip options