$74 Car Rental Palmyra, MO

These Palmyra insights are based on real traveler data from Expedia, aggregated using AI to help you plan your trip. Updated: August 29, 2026.

Reasons to book a car rental in and around Palmyra

Renting a car in Palmyra offers the freedom and flexibility to explore the area at your own pace. With a rental car, you can easily manage your luggage while visiting attractions like Big Spring Park, a family-friendly urban park, or the Gardner House Museum, which provides a glimpse into local culture. For those seeking outdoor experiences, Murphy Island is a great destination. Furthermore, having a car allows you to venture into nearby cities such as Hannibal, located 10 miles away, where you can visit the Mark Twain Boyhood Home and Museum or explore the Mark Twain Cave. Quincy, just 11 miles from Palmyra, features the stunning Villa Katherine Castle and Washington Park, while Rensselaer, 9 miles away, offers Bear Creek Park and more cultural experiences. Whether you're traveling with family, looking for romantic spots, or seeking outdoor scenery, renting a car ensures you can explore these attractions conveniently and comfortably. Enjoy the ability to create your own travel plans without relying on public transportation, making your visit to Palmyra a more enjoyable experience.

Where to stay around Palmyra

• Hannibal: Located 10 miles away from Palmyra, Hannibal offers a charming blend of outdoor activities and historic sites. Travelers can explore the Mark Twain Boyhood Home and Museum for a cultural experience or venture into the Mark Twain Cave for outdoor adventure. The scenic Rockcliffe Mansion also provides a glimpse into the area’s rich history. With nearby wineries and restaurants, Hannibal is perfect for those looking for a romantic getaway or scenic outings, especially in the spring and fall when the weather is ideal for exploration.
• Quincy: Situated 11 miles from Palmyra, Quincy is a vibrant city known for its cultural experiences and beautiful scenery. Visitors can discover the historic Villa Katherine Castle and enjoy the peaceful Washington Park. Quincy also boasts a range of shopping centers and eateries, including local wineries and restaurants. The spring and summer months are particularly enjoyable for outdoor activities and events, making Quincy a great choice for travelers seeking both relaxation and cultural engagement.
• Monroe City: About 15 miles from Palmyra, Monroe City is renowned for its romantic scenery and outdoor recreational opportunities. The beautiful Mark Twain Lake offers a serene setting for beach outings, while the Mark Twain State Park provides excellent trails for adventure seekers. With nearby wineries and restaurants, Monroe City is an ideal destination for couples and nature lovers, especially during the warmer months when the lakes and parks are most inviting.

10 tips to save on your car rental in and around Palmyra

1. Use filters to find the right car: Refine your search by vehicle type and features. Whether you need an SUV for added space, a convertible for summer drives, or an economy car for budget-friendly travel, utilize the filters on Expedia to locate the best option for your journey.
2. Book in advance to help lower costs: Rental prices can vary based on demand, so it's advisable to secure your car well ahead of your trip. By booking early, you’re more likely to obtain lower rates and have a wider selection, particularly during peak seasons.
3. Consider a smaller car for savings: Smaller vehicles are typically less expensive to rent and easier to maneuver in crowded areas. Mid-size rentals strike a good balance between cost, comfort, and fuel efficiency.
4. Age guidelines: Drivers under 30 may encounter higher deposits or daily surcharges, and certain vehicle categories—such as SUVs or premium models—might not be available. This can also apply to renters over 70. Always verify the age requirements before making a reservation.
5. Check fuel policies: Some rental agreements require a full-to-full fuel policy, meaning you must return the car with a full tank to avoid additional charges. This is generally the most economical choice. Others may provide full-to-empty or prepaid fueling options, which are acceptable as well; just be sure to return the car empty in that case.
6. Save on city and airport pickups: There is often an extra fee for picking up your rental car at airports, but the added convenience might make it worthwhile.
7. Know your payment options: Many car rental companies exclusively accept credit cards for payment.
8. Understand your insurance coverage: Car rental insurance can help you avoid unexpected costs and provides peace of mind in case of unforeseen events during your trip. It's easy to add car rental insurance when booking with Expedia.
9. Consider unlimited mileage: If you plan on taking long road trips, look for rentals that offer unlimited mileage to steer clear of additional charges.
10. Bring your driver's license and ID: A valid driver's license is necessary to rent a car.

Finding the cheapest car rentals in Palmyra

Using our Search Wizard

If the deals that are available on our page do not suit your needs, then enter Palmyra into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Palmyra and provide you with a list of the cheapest options, with no added fees.

Renting a car in Palmyra

Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Palmyra. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.

Expected prices in Palmyra

Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $74.

Flexibility & Cancellation

Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.

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Car classes available from Expedia in 2026

The classes of vehicles available will change depending on your chosen location.

• Compact car rentals    
• Convertible car rentals    
• Economy car rentals    
• Fullsize car rentals    
• Luxury car rentals
• Midsize car rentals    
• Mini car rentals    
• Minivan rentals    
• Pickup car rentals    
• Premium car rentals
• Sportscar rentals    
• Standard car rentals    
• SUV rentals    
• Van rentals