San Marco Vacations from $562

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Your San Marco Vacation

Avoid the hassle of travel planning with a San Marco vacation package. With all the details locked in before you take off, all you have to do is enjoy this leafy neighborhood's bars and pubs, cafes and culture. Your trip to San Marco wouldn't be complete without stopping by popular attractions nearby such as Orange Park Place Shopping Center, Theatre Jacksonville and Fort Caroline Shopping Center. Stop daydreaming and start doing. When it's time to lock in your ideal vacation to San Marco, Expedia will help get you there.

The Latest San Marco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Tricove Inn & Suites

Tricove Inn & Suites

Southside
$562
per person
Sep 15 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Indianapolis (IND) to Jacksonville (JAX)
7.4/10 Good! (1,007 reviews)
Amelia by the Sea

Amelia by the Sea

Save 100% on your flight
$2,815
per person
Oct 17 - Oct 20
found 1 day ago
Roundtrip flight included
New York (NYC) to Jacksonville (JAX)
No reviews
Amelia by the South

Amelia by the South

Save 100% on your flight
$2,622
per person
Oct 7 - Oct 14
found 1 day ago
Roundtrip flight included
Boston (BOS) to Jacksonville (JAX)
No reviews
Southbank Apartments by Landing

Southbank Apartments by Landing

Downtown Jacksonville
$760
per person
Sep 11 - Sep 18
found 1 day ago
Roundtrip flight included
Boston (BOS) to Jacksonville (JAX)
10/10 Exceptional! (1 review)
The check in process was very confusing but the visa

Reviewed on Apr 4, 2026

Landing Jacksonville

Landing Jacksonville

Sunbeam
$706
per person
Sep 11 - Sep 18
found 1 day ago
Roundtrip flight included
Boston (BOS) to Jacksonville (JAX)
7/10 Good! (2 reviews)
Room hardwares and cleaness very good, but Landing App did not properly work, not easy to link up with the landlord/agent for check-in/check-out process.

Reviewed on Mar 25, 2026

Where to stay in San Marco

Find the best San Marco areas and neighborhoods for the activities you enjoy most. Learn more about San Marco
A coastal town at dusk with a prominent clock tower, waterfront, and illuminated buildings.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

A sunset over a beach with waves and a pier.

Oceanfront

1 out of top 10 points of interest in this area

If you're spending some time in Oceanfront, Oceanfront Park and Northeast Florida Beaches are top sights worth seeing.

A city skyline with modern skyscrapers, a prominent Wells Fargo building, and a blue bridge over a river.

Downtown Jacksonville

2 out of top 10 points of interest in this area

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

A river with a bridge, a marina with boats, and a city skyline with high-rise buildings.

Southside

1 out of top 10 points of interest in this area

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

A golf course with a pond, trees, and buildings in the background.

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

San Marco Hotel Deals

Scottish Inn Jacksonville Downtown

Scottish Inn Jacksonville Downtown

2300 Phillips Hwy Jacksonville FL
Fully refundableReserve now, pay when you stay
$44 nightly
$50 total
Aug 9 - Aug 10
Total with taxes and fees
Scottish Inn Jacksonville Downtown
Hilton Garden Inn Jacksonville Downtown Southbank

Hilton Garden Inn Jacksonville Downtown Southbank

1201 Kings Avenue Jacksonville FL
Fully refundableReserve now, pay when you stay
$90 nightly
$102 total
Aug 16 - Aug 17
Total with taxes and fees
8.4/10 Very Good! (1,005 reviews)
"The room was very clean and the guest service agent on Friday was excellent."

Reviewed on Aug 3, 2026

Hilton Garden Inn Jacksonville Downtown Southbank
Homewood Suites by Hilton Jacksonville Downtown-Southbank

Homewood Suites by Hilton Jacksonville Downtown-Southbank

1201 Kings Avenue Jacksonville FL
Fully refundableReserve now, pay when you stay
$122 nightly
$139 total
Aug 16 - Aug 17
Total with taxes and fees
8.6/10 Excellent! (872 reviews)
"The lady at the front desk was joyful and inviting. Her name was Artarshia, I believe. The gentleman in charge of the breakfast was also very Superb. Such a friendly, respectful and kind man. The sort of man you find yourself going out of your way to try to express Respect to:)"

Reviewed on Aug 3, 2026

Homewood Suites by Hilton Jacksonville Downtown-Southbank
See all 3,059 properties in San Marco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular San Marco attractions

Theatre Jacksonville

You can make plans for a show at Theatre Jacksonville during your trip to Jacksonville. Amble around this vibrant area's riverfront or attend a sporting event.
See properties

Jack Rabbits Live

You can enjoy a show at Jack Rabbits Live on your trip to Jacksonville. Attend a sporting event in this family-friendly area, or simply enjoy its bars.
See properties

Things to do

The Escape Game at St. John's Town Center in Jacksonville

The Escape Game at St. John's Town Center in Jacksonville

$42
per adult
100% of travellers recommend
The Escape Game at St. John's Town Center in Jacksonville
1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports

1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports

$145
per traveler
90% of travellers recommend
1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports
Half-Day City Tour in Downtown Jacksonville

Half-Day City Tour in Downtown Jacksonville

$115
per adult
100% of travellers recommend
Half-Day City Tour in Downtown Jacksonville
See all activities in Jacksonville

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.