Santa Ana

Panama City

Plaza Santa Ana, Panama Casco Viejo
View from the fish market
go there and eat fresh and yummy fish in all variations

Popular places to visit

Things to do


Santa Ana Hotel Deals

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
$114 nightly
The price is $125 total per night from Mar 30 to Mar 31
$125 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Cinta Costera ...
9/10 Wonderful! (78 reviews)
Honest review of apartments clean well organized minimalist, but with ok essentials in the kitchens, paper towels., few cleaning supplies look under sink., everything neat in and order. Large sliding glass window, but the view is of interesting neighborhood) ocean (window in bedroom is to hallway) ...

Reviewed on Mar 6, 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
$157 nightly
The price is $172 total per night from Mar 30 to Mar 31
$172 total
Mar 30 - Mar 31
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (5,082 reviews)
I stayed for 3 nights, and the room was not cleaned during my stay. There was no toothbrush, no slippers, no comb, and no cotton swabs provided. I have call them for new towels

Reviewed on Mar 13, 2026

Hotel Riu Plaza Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
$127 nightly
The price is $139 total per night from Apr 3 to Apr 4
$139 total
Apr 3 - Apr 4
Total with taxes and fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,004 reviews)
The hotel is a bit off the main areas, need to use uber to get to downtown. Other than that, every thing was awesome. this was a birthday trip, so I mentioned its my birthday and was given some delicious deserts. That was an awesome gesture. Thank you Sheraton for making my birthday extra ...

Reviewed on Mar 13, 2026

Sheraton Grand Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
$135 nightly
The price is $149 total per night from Apr 13 to Apr 14
$149 total
Apr 13 - Apr 14
Total with taxes and fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (2,474 reviews)
No occan view at all. A dirty roof top and lame backyard. Food was blah.

Reviewed on Mar 13, 2026

Crowne Plaza Panama Airport by IHG
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
$108 nightly
The price is $119 total per night from Mar 23 to Mar 24
$119 total
Mar 23 - Mar 24
Total with taxes and fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,003 reviews)
Yes

Reviewed on Mar 12, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
$199 nightly
The price is $219 total per night from Mar 31 to Apr 1
$219 total
Mar 31 - Apr 1
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,005 reviews)
Great place if you enjoy music blasting until 2–3 a.m. and involuntary participation in your neighbors’ intimate moments all night long. Not ideal if you’re hoping for sleep or privacy.

Reviewed on Mar 13, 2026

W Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Vacation Sale

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Other neighborhoods around Santa Ana

View of the Panama City Old Town

Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

San Felipe
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El Chorrillo

While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Maracana Stadium and Flag of Cerro Ancón.

El Chorrillo
The skyline at Panama City, Panama. There are some nice walkways along the waterfront.

Calidonia

You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Calidonia
The buses of Panama.

Balboa

The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Flag of Cerro Ancón and Bridge of the Americas, a few notable attractions nearby.

Balboa
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Curundu

While Curundu isn't home to many top sights, Iglesia del Carmen and Via Espana are some notable places to visit nearby.

Curundu


Santa Ana

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