Title: Santa Fe Island Vacation Rentals from $76: Search Short-Term Rentals | Expedia.com

[Santa Fe Island Travel Guide](https://expedia.com/Santa-Fe-Island.dx6336630)[Hotels in Santa Fe Island](https://expedia.com/Santa-Fe-Island-Hotels.d6336630.Travel-Guide-Hotels)[Flights to Santa Fe Island](https://expedia.com/Cheap-Flights-To-Santa-Fe-Island.d6336630.Travel-Guide-Flights)[Car Rentals in Santa Fe Island](https://expedia.com/Car-Rentals-In-Santa-Fe-Island.d6336630.Car-Rental-Guide)[Santa Fe Island Vacation Packages](https://expedia.com/Santa-Fe-Island.d6336630.Destination-Travel-Guides)

![Seal lions 😍 #aquatrove](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Elizabeth Oates

![](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6336630&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=6336630&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=6336630&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=6336630&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Fe Island vacation rentals

![Exterior](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/9468ea94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Quadruple Room, 1 Bedroom | Private kitchen | Fridge, oven, rice cooker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/7ebdf614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Quadruple Room, 1 Bedroom | 1 bedroom, down comforters, individually furnished, blackout drapes](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/95d1d08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Suite | 1 bedroom, down comforters, individually furnished, blackout drapes](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/48fd3b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Suites

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites.h34937768.Hotel-Information)

Puerto Ayora

9.4/10

Exceptional

(24 reviews)

"Check was early and friendly staff Room was super clean and comfortable"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judy

$92 nightly

$92 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites.h34937768.Hotel-Information)

![Family Duplex, 2 Bedrooms, Private Bathroom, Garden View (Courtyard ) | Terrace/patio](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/ffb9bce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Ensuite (One bedroom King) | Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/34c553bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/392aa62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/aabb8b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Torre Mar Galapagos Boutique Suites

[](https://www.expedia.com/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Boutique-Suites.h16786878.Hotel-Information)

Puerto Ayora

9.2/10

Wonderful

(19 reviews)

"Very nice suite, clean, quiet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Masoud

$114 nightly

$114 total

Feb 26 - Feb 27

[](https://www.expedia.com/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Boutique-Suites.h16786878.Hotel-Information)

![Luxury Apartment, Balcony | Living area | LCD TV, Netflix, pay movies, streaming services](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/39eae50b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/987560e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment, Balcony | Living area | LCD TV, Netflix, pay movies, streaming services](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/7209e130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment, Balcony | Balcony](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/992ac688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galapagos Coliving Ecuador Casa Tuna

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galapagos-Coliving-Ecuador-Casa-Tuna.h106882041.Hotel-Information)

Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galapagos-Coliving-Ecuador-Casa-Tuna.h106882041.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/a58537c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/d98281b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/d3c64b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/b8157967.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Queen Bedroom Suite ON THE Second High Floor AT Ariana\`s Galapagos Hostal

[](https://www.expedia.com/Puerto-Ayora-Hotels-Queen-Bedroom-Suite-ON-THE-Second-High-Floor-AT-Arianas-Galapagos-Hostal.h102780548.Hotel-Information)

Puerto Ayora

$69 nightly

$76 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Queen-Bedroom-Suite-ON-THE-Second-High-Floor-AT-Arianas-Galapagos-Hostal.h102780548.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/0d9fc98c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/2d5538fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, coffee/tea maker, cookware/dishes/utensils, lobster pot](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/80603d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/236b5ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment near the Sea

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites-Cerca-Del-Mar.h50883187.Hotel-Information)

PUERTO AYORA SANTA CRUZ GALAPAGOS

8.8/10

Excellent

(5 reviews)

"Really nice place!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sefora

$130 nightly

$170 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites-Cerca-Del-Mar.h50883187.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/e27d3e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/41f41cf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/8508134b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/735d660b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ¡Bienvenido a tu hogar isleño en Galápagos! 

[](https://www.expedia.com/Puerto-Ayora-Hotels-Bienvenido-A-Tu-Hogar-Isleno-En-Galapagos.h100177018.Hotel-Information)

Puerto Ayora

$102 nightly

$102 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Bienvenido-A-Tu-Hogar-Isleno-En-Galapagos.h100177018.Hotel-Information)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f0249e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/5b0760b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f1c0fb19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, coffee/tea maker, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/6f52aa05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Vacacional en Puerto Ayora, Santa Cruz, Galápagos

[](https://www.expedia.com/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information)

Puerto Ayora

10/10

Exceptional

(1 review)

"Nice and beautiful house to stay very impressed "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

$121 nightly

$121 total

Mar 1 - Mar 2

[](https://www.expedia.com/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/1f94b12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Townhome, 1 Bedroom, Non Smoking, City View | 2 bedrooms, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2847ed9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2ad1a614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/369f220c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Galapagos

[](https://www.expedia.com/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information)

Puerto Ayora

6.0/10

(1 review)

"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"

![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg)

アオアシカツオドリ

$105 nightly

$105 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information)

![1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/82ca6a97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/a7583985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/c896c6c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/ce69d14a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galarous Island Suite comfortable and cozy 

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Servirle-Con-Calidad-Y-Calidez-En-Su-Casa.h59688686.Hotel-Information)

Puerto Ayora

$56 nightly

$56 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Servirle-Con-Calidad-Y-Calidez-En-Su-Casa.h59688686.Hotel-Information)

![1 bedroom, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/1213239e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/3ed3ea89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/b1d46278.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/e5ff1a0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galarous island apartments

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Island-Apartments.h59677109.Hotel-Information)

Puerto Ayora

$130 nightly

$130 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Island-Apartments.h59677109.Hotel-Information)

![1 bedroom, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/fae3fe2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/9ae4b365.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/ecab4b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/c1ad2cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galarous serve you with quality and warmth in your home

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Serve-You-With-Quality-And-Warmth-In-Your-Home.h60597196.Hotel-Information)

Puerto Ayora

$120 nightly

$120 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Serve-You-With-Quality-And-Warmth-In-Your-Home.h60597196.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/102000000/101500000/101495500/101495451/fdcabf70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101500000/101495500/101495451/ea0beeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101500000/101495500/101495451/f2ee306a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/102000000/101500000/101495500/101495451/33fb0ce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Panoramic Rooms at Galapagos Verde Azul

[](https://www.expedia.com/Puerto-Ayora-Hotels-Panoramic-Rooms-At-Galapagos-Verde-Azul.h101495451.Hotel-Information)

Puerto Ayora

$205 nightly

$232 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Panoramic-Rooms-At-Galapagos-Verde-Azul.h101495451.Hotel-Information)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/406de75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/7a5abddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/6408dac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/baa439a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TWO Bedrooms Apartment ON THE First Floor IN Ariana\`s Galapagos Hostal

[](https://www.expedia.com/Puerto-Ayora-Hotels-TWO-Bedrooms-Apartment-ON-THE-First-Floor-IN-Arianas-Galapagos-Hostal.h103058515.Hotel-Information)

Puerto Ayora

$89 nightly

$99 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-TWO-Bedrooms-Apartment-ON-THE-First-Floor-IN-Arianas-Galapagos-Hostal.h103058515.Hotel-Information)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/c866cc9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/b737e9c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/5e3e1504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/43162e8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Imagination Studio Home

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h124393435.Hotel-Information)

Puerto Ayora

$324 nightly

$363 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h124393435.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/ac8a7bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/3543098c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/3200cd5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/ee9d32a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-2-Bedroom-Apartment-With-AC.h112677301.Hotel-Information)

Puerto Ayora

$88 nightly

$88 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-2-Bedroom-Apartment-With-AC.h112677301.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/102000000/101740000/101738700/101738687/734f5e24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, stereo](https://images.trvl-media.com/lodging/102000000/101740000/101738700/101738687/066e0040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101740000/101738700/101738687/5646c61b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, stereo](https://images.trvl-media.com/lodging/102000000/101740000/101738700/101738687/0cd636bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Endemic Suite - Apartamento con Azotea Vista 360

[](https://www.expedia.com/Puerto-Ayora-Hotels-Endemic-Suite-Apartamento-Con-Azotea-Vista-360.h101738687.Hotel-Information)

Puerto Ayora

$85 nightly

$85 total

Mar 1 - Mar 2

[](https://www.expedia.com/Puerto-Ayora-Hotels-Endemic-Suite-Apartamento-Con-Azotea-Vista-360.h101738687.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/ebf60a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/753f38a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/46b3f49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/b574e039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Two Bedroom house - The Galapagos Pearl Hotel

[](https://www.expedia.com/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information)

Puerto Ayora

10/10

Exceptional

(1 review)

"We stayed 3 nights in the "casa grande" associated with the Galapagos Pearl Hotel and could not have been more pleased. The casa has 2 bedrooms, a small kitchen, one bathroom, and is conveniently located right next to the pool and the outdoor dining area where Yolanda serves breakfast. Your room is cleaned every day. The garden surrounding the pool and casa is lush and full of geckos, cats, and beautiful plantings. Yolanda is from the Galapagos, she is a wonderful host and her daughter helped us...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura E.

$228 nightly

$252 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/9465b582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, stovetop, coffee/tea maker, blender](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/a87cb59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/343f2f1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/daa6d638.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TWO Bedrooms Apartment ON THE Ground Floor IN Ariana\`s Galapagos Hostal

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h102721840.Hotel-Information)

Puerto Ayora

10/10

Exceptional

(1 review)

"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Dean P.

$89 nightly

$99 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h102721840.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/104000000/103430000/103424700/103424658/784c1849.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103430000/103424700/103424658/98c3994e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/104000000/103430000/103424700/103424658/bea60ccd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103430000/103424700/103424658/45bbaa21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### KING SIZE BED & TWIN SIZE BED WITH PRIVATE BATHROOM ON SECOND FLOOR

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h103424658.Hotel-Information)

Puerto Ayora

$50 nightly

$55 total

Feb 26 - Feb 27

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h103424658.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/e9b7ef2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/4776976b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/8b0d2620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/a5ec6899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### GALAPAGOS DIVER ESTUDIO.

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h110134025.Hotel-Information)

Puerto Ayora

10/10

Exceptional

(1 review)

"Perfect start to finish. Very clean! Drinking water provided. The host helped us with a small hiccup regarding our transfer so we were able to catch the ferry to San Cristóbal with no problem. Highly recommend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shannyn Z.

$90 nightly

$90 total

Feb 24 - Feb 25

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h110134025.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-09&endDate=2026-03-10&regionId=6336630&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=CABIN)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=APARTMENT)

Villas

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=VILLA)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=CONDO)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-05-24&d1=2026-05-24&endDate=2026-05-27&d2=2026-05-27&lodging=VACATION_HOME)

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## Top Santa Fe Island Hotel Reviews

![Galapagos Dreams](https://images.trvl-media.com/lodging/12000000/11700000/11698100/11698055/6897639d_y.jpg)

### Galapagos Dreams

10/10 Excellent

"Great staff, incredibly helpful."

[](https://expedia.com/Puerto-Ayora-Hotels-GALAPAGOS-DREAMS.h11698055.Hotel-Information)

![El Barranco Galapagos](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/910f927d_y.jpg)

### El Barranco Galapagos

10/10 Excellent

"El Barranco Galapagos is a fantastic hotel! Breakfasts were delicious the staff friendly and accommodating, the location excellent for dining shopping and access to tours from the wharf. Our maid even did our laundry! We stayed in the family cabin which included a kitchen 4 bedrooms a hot tub and its own patio. It was spotless! We hated to leave!"

[](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Barranco-Galapagos.h111508035.Hotel-Information)

![Galapagos Verde Azul](https://images.trvl-media.com/lodging/10000000/9580000/9577600/9577577/6a115ff5_y.jpg)

### Galapagos Verde Azul

10/10 Excellent

"The rooms were big and well kept. The staff was awesome. The location was quiet and we could walk to the beach. "

[](https://expedia.com/Puerto-Ayora-Hotels-Galapagos-Verde-Azul.h9577577.Hotel-Information)

![Ikala Galapagos Hotel](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/ecbf00ed_y.jpg)

### Ikala Galapagos Hotel

10/10 Excellent

"Hotel was excellent staff was great accomodations perfect"

[](https://expedia.com/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information)

![Posada del Mar](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/e7fb3ff1_y.jpg)

### Posada del Mar

10/10 Excellent

"Carlos at reception was excellent. Earplugs given at checkin for the late night party (3am municipal at the docks). Help and advice when we couldn’t reach our tour contact. Clean and spacious room, efficient and quiet AC, amazing view, nice breakfast. Bed was a little hard by North American standards but quite comfortable "

[](https://expedia.com/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information)

![Hotel Fiesta](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/b440b32f_y.jpg)

### Hotel Fiesta

10/10 Excellent

"Everything was wonderful, rooms are small but we hardly spent any time in it and the bed was just fine to fall asleep on after a long day of adventures! Rooms are well cleaned as well towels. Pool area is great, location is nice and quiet but easy walking distance to anything. "

[](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information)

![Hotel Ninfa](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/08eca00e_y.jpg)

### Hotel Ninfa

10/10 Excellent

"Great spot, close to everything in "

[](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information)

![Capitan Max B&B](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48_y.jpg)

### Capitan Max B&B

10/10 Excellent

"I was feeling like in home at this place. I recommend for somebody that get an excellent service and staff. "

[](https://expedia.com/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information)

![Hotel el descanso del Guia](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/b6171efd_y.jpg)

### Hotel el descanso del Guia

10/10 Excellent

"Rooms were clean and spacious. Staff were friendly and very accommodating. Price was very reasonable. Pool was great."

[](https://expedia.com/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information)

## Find out more about Santa Fe Island

**Everything you need to know about Santa Fe Island vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Fe Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Fe Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santa Fe Island vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santa Fe Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Fe Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $76 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santa Fe Island rentals**

At Expedia, we put the best Santa Fe Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Fe Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Fe Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Fe Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Santa Fe Island

### Trending destinations on Expedia.com

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- [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals)
- [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals)
- [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals)
- [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)
- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Apartments in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Apartments.d6336630-aaApartments.Travel-Guide-Accommodation)
- [Vacation Homes in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Private-Vacation-Homes.d6336630-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [B&B in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Bed-And-Breakfast.d6336630-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Aparthotels in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Apart-Hotels.d6336630-aaApartHotels.Travel-Guide-Accommodation)
- [Guest Houses in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Guest-Houses.d6336630-aaGuestHouses.Travel-Guide-Accommodation)
- [Cottages in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Cottages.d6336630-aaCottages.Travel-Guide-Accommodation)
- [Hostels in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Hostels.d6336630-aaHostels.Travel-Guide-Accommodation)
- [Villas in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Villas.d6336630-aaVillas.Travel-Guide-Accommodation)
- [Lodges in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Lodges.d6336630-aaLodges.Travel-Guide-Accommodation)
- [Resorts in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Resorts.d6336630-aaResorts.Travel-Guide-Accommodation)
- [Condo Rentals in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Condos.d6336630-aaCondos.Travel-Guide-Accommodation)
- [Cabin Rentals in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Cabins.d6336630-aaCabins.Travel-Guide-Accommodation)

### Expedia's Latest Trends

Hotels

- [Hotels in Floreana Island](https://expedia.com/Floreana-Island-Hotels.d6336634.Travel-Guide-Hotels)
- [Hotels in Rabida Island](https://expedia.com/Rabida-Island-Hotels.d6336653.Travel-Guide-Hotels)
- [San Cristobal Island Oceanfront Hotels](https://expedia.com/San-Cristobal-Island-Hotels-Oceanfront-Hotels.0-0-d6138895-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
- [Hotels in San Cristobal Island](https://expedia.com/San-Cristobal-Island-Hotels.d6138895.Travel-Guide-Hotels)
- [Isabela Island Cheap Hotels](https://expedia.com/Isabela-Island-Hotels-Cheap-Hotels.0-0-d6085329-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Santa Cruz Island Family Hotels](https://expedia.com/Santa-Cruz-Island-Hotels-Family-Hotel.0-0-d6053670-tFamilyHotel.Travel-Guide-Filter-Hotels)
- [Isabela Island Family Hotels](https://expedia.com/Isabela-Island-Hotels-Family-Hotel.0-0-d6085329-tFamilyHotel.Travel-Guide-Filter-Hotels)
- [Hotels in Isabela Island](https://expedia.com/Isabela-Island-Hotels.d6085329.Travel-Guide-Hotels)
- [Hotels in Espanola Island](https://expedia.com/Espanola-Island-Hotels.d6336647.Travel-Guide-Hotels)
- [Floreana Island Hotels with Restaurants](https://expedia.com/Floreana-Island-Hotels-Hotels-With-Restaurants.0-0-d6336634-tHotelswithRestaurants.Travel-Guide-Filter-Hotels)
- [San Cristobal Island Hotels with a Pool](https://expedia.com/San-Cristobal-Island-Hotels-Hotel-With-Pool.0-0-d6138895-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Santa Cruz Island 3 Star Hotels](https://expedia.com/3Star-Santa-Cruz-Island-Hotels.s30-0-d6053670.Travel-Guide-Filter-Hotels)
- [Hotels in Santa Cruz Island](https://expedia.com/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)
- [Santiago Island 4 Star Hotels](https://expedia.com/4Star-Santiago-Island-Hotels.s40-0-d6336381.Travel-Guide-Filter-Hotels)

Flights

- [Flights to Santa Cruz Island](https://expedia.com/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)
- [Flights to Isabela Island](https://expedia.com/Cheap-Flights-To-Isabela-Island.d6085329.Travel-Guide-Flights)

Cars

- [Car rentals in Floreana Island](https://expedia.com/Car-Rentals-In-Floreana-Island.d6336634.Car-Rental-Guide)
- [Car rentals in San Cristobal Island](https://expedia.com/Car-Rentals-In-San-Cristobal-Island.d6138895.Car-Rental-Guide)

Activities

- [Things to do in Isabela Island](https://expedia.com/Things-To-Do-In-Isabela-Island.d6085329.Travel-Guide-Activities)
- [Things to do in Santa Cruz Island](https://expedia.com/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)

Packages

- [Floreana Island Vacation](https://expedia.com/Floreana-Island.d6336634.Destination-Travel-Guides)
- [Bartolome Island Vacation](https://expedia.com/Bartolome-Island.d6336382.Destination-Travel-Guides)
- [Santiago Island Vacation](https://expedia.com/Santiago-Island.d6336381.Destination-Travel-Guides)
- [Isabela Island Vacation](https://expedia.com/Isabela-Island.d6085329.Destination-Travel-Guides)

General

- [Visit Espanola Island](https://expedia.com/Espanola-Island.dx6336647)
- [Visit San Cristobal Island](https://expedia.com/San-Cristobal-Island.dx6138895)
- [Visit Santiago Island](https://expedia.com/Santiago-Island.dx6336381)
- [Visit Bartolome Island](https://expedia.com/Bartolome-Island.dx6336382)
- [Visit Floreana Island](https://expedia.com/Floreana-Island.dx6336634)
- [Visit Santa Cruz Island](https://expedia.com/Santa-Cruz-Island.dx6053670)

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## Go further with the Expedia app

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