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Our top choices for Santa Maria hotels

Hotel del Parque

Hotel del Parque
4.5 star property
4.4 mi from Santa Maria
9.8 out of 10, Exceptional, (112 reviews)
"Friendly staff. We arrived very early and they were ablemto accommodate an early check-in. The hotel is beautiful "
Canada
Victor
$429 nightly
The price is $472
Apr 13 - Apr 14
Hotel del Parque

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 4.9 mi from Santa Maria
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
$345 nightly
The price is $380
Apr 13 - Apr 14
Hotel Río Guayas by Art Hotels Ecuador

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.4 mi from Santa Maria
9.4 out of 10, Exceptional, (1,011 reviews)
"Perfect hotel for my overnight layover. 24-hour room service; helpful staff; easy and easily available shuttle to the airport. Would stay again."
United States
Alexander
$92 nightly
The price is $104
May 3 - May 4
Holiday Inn Guayaquil Airport by IHG

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 4.7 mi from Santa Maria
9.2 out of 10, Wonderful, (1,005 reviews)
"Attentive staff and excellent breakfast and amenities."
United States
Mario
$100 nightly
The price is $112
Apr 26 - Apr 27
Wyndham Guayaquil Puerto Santa Ana

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
3.5 mi from Santa Maria
$52 nightly
The price is $53
Apr 20 - Apr 21
NP Hotel & Suites

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
1.8 mi from Santa Maria
9.2 out of 10, Wonderful, (47 reviews)
"A lovely oasis in the city. Very relaxing and friendly service."
United States
Landy
$59 nightly
The price is $65
Apr 13 - Apr 14
Iguanazu Bed & Breakfast

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 3 mi from Santa Maria
9.0 out of 10, Wonderful, (637 reviews)
"Very nice place to stay ! "
United States
Diana
$90 nightly
The price is $102
Apr 17 - Apr 18
Sheraton Guayaquil Hotel

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 2.6 mi from Santa Maria
8.8 out of 10, Excellent, (888 reviews)
"convenient place and clean"
United States
Allyson
$97 nightly
The price is $109
Apr 19 - Apr 20
Hilton Colon Guayaquil

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 4.3 mi from Santa Maria
9.4 out of 10, Exceptional, (1,003 reviews)
"Great staff!"
United States
Jeanette
$80 nightly
The price is $91
Apr 17 - Apr 18
Oro Verde Guayaquil

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
6.1 mi from Santa Maria
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
$48 nightly
The price is $48
Apr 13 - Apr 14
Hotel La Ria Durán

Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 3.1 mi from Santa Maria
8.6 out of 10, Excellent, (247 reviews)
"Clean, excellent service, great food!"
United States
Wilson
$55 nightly
The price is $56
Apr 17 - Apr 18
Hotel Puerto Pacifico Guayaquil Airport

Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 2.9 mi from Santa Maria
9.4 out of 10, Exceptional, (179 reviews)
"Clean room, staff, location"
United States
Veronica
$86 nightly
The price is $87
Apr 14 - Apr 15
Luxva Hotel Boutique

Villa Celeste - VC

Villa Celeste - VC
2.5 star property
5.8 mi from Santa Maria
7.4 out of 10, Good, (13 reviews)
"It is a good place, they respect your privacity and has a good communication with tourist places "
Mexico
Moises Reque
$16 nightly
The price is $16
Apr 13 - Apr 14
Villa Celeste - VC

Casa Veranda

Casa Veranda
2.5 star property
5.6 mi from Santa Maria
$30 nightly
The price is $30
Apr 20 - Apr 21
Casa Veranda

Grand Hotel Guayaquil, an Ascend Collection Hotel

Grand Hotel Guayaquil, an Ascend Collection Hotel
4.0 star property
Rocafuerte, 4.9 mi from Santa Maria
9.2 out of 10, Wonderful, (1,004 reviews)
"Nice place to stay. "
United States
Joanna
$84 nightly
The price is $94
Apr 17 - Apr 18
Grand Hotel Guayaquil, an Ascend Collection Hotel

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 3 mi from Santa Maria
9.0 out of 10, Wonderful, (1,005 reviews)
"Very pleasant hotel - great location and excellent staff - room quiet and clean"
United States
Charles
$85 nightly
The price is $96
Apr 19 - Apr 20
TRYP by Wyndham Guayaquil Airport

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 3 mi from Santa Maria
9.2 out of 10, Wonderful, (1,001 reviews)
"Excellent choice of hotel. Easy access from airport, friendly staff and excellent breakfast."
United States
Gerald
$75 nightly
The price is $84
Apr 26 - Apr 27
Wyndham Garden Guayaquil

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 4.9 mi from Santa Maria
8.8 out of 10, Excellent, (136 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
$58 nightly
The price is $65
Apr 30 - May 1
Mansión del Río

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 3.2 mi from Santa Maria
9.0 out of 10, Wonderful, (616 reviews)
"Clean room and nice staff"
United States
JUAN BERNARDO
$34 nightly
The price is $35
May 1 - May 2
DC Suites Aeropuerto

Guayacan Apart Hotel

Guayacan Apart Hotel
2.0 star property
Downtown Guayaquil, 4.7 mi from Santa Maria
$40 nightly
The price is $40
Apr 13 - Apr 14
Guayacan Apart Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Numa Pompilio Llona Street while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

Bolívar

While Bolívar isn't home to many top sights, Central Market and Malecon Mall are some notable places to visit nearby.

Top Santa Maria Hotel Reviews

Frequently asked questions

What other neighbourhoods are similar to Santa Maria?
While Santa Maria offers a particular experience, neighborhoods in Guayaquil like Urdesa and Samborondón provide similar characteristics, making them excellent alternatives for travelers seeking quality and convenience.

Urdesa is a well-established residential and commercial area known for its tree-lined streets and a wide array of dining options, particularly along Victor Emilio Estrada Avenue. It's a great choice for couples or solo travelers who appreciate a relaxed yet sophisticated setting with easy access to restaurants, cafes, and boutiques. The neighborhood has a pleasant, pedestrian-friendly layout for evening strolls.

Samborondón, located across the Daule River from Guayaquil, offers a more modern and upscale experience. This area is characterized by its planned communities, shopping centers like Plaza Lagos Town Center, and numerous high-end restaurants. It's particularly appealing to families due to its spacious feel, green areas, and a focus on contemporary amenities.
When is the best time to go to Santa Maria?
The best time to go to Santa Maria, Guayas, Ecuador, is during the dry season, which typically runs from June to December.

During these months, you'll experience less rainfall and more sunshine, making it ideal for exploring the natural beauty and outdoor activities the region offers. The weather is generally warm and pleasant, superb for visiting the nearby beaches or enjoying excursions into the surrounding countryside.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Maria.
How can I save on a Santa Maria hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Santa Maria hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Maria hotel?
Prices for hotels in Santa Maria often vary, but you can find a great deal on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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