Find hotels in Santa Maria, Guayaquil

Check prices for these dates

Tonight
Feb 5 - Feb 6
Tomorrow
Feb 6 - Feb 7
This weekend
Feb 6 - Feb 8
Next weekend
Feb 13 - Feb 15

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Maria hotels

Family House, Private Pool | Living area | Flat-screen TV

Casa con Piscina Privada para Familias

Casa con Piscina Privada para Familias
3.0 star property
8.5 mi from Santa Maria
2.0 out of 10, (2 reviews)
"More cleaning, there was rotten garbage and a bad smell emanated"
United States
Isabel
$135 nightly
The price is $135
Feb 9 - Feb 10
Casa con Piscina Privada para Familias
Terrace/patio

Villa Celeste - VC

Villa Celeste - VC
2.5 star property
5.8 mi from Santa Maria
7.4 out of 10, Good, (13 reviews)
"It is a good place, they respect your privacity and has a good communication with tourist places "
Mexico
Moises Reque
$16 nightly
The price is $16
Feb 6 - Feb 7
Villa Celeste - VC
Economy Double Room | In-room safe, free WiFi

Malecon Guesthouse

Malecon Guesthouse
3.0 star property
River City, 4.9 mi from Santa Maria
$24 nightly
The price is $25
Feb 6 - Feb 7
Malecon Guesthouse
Exterior

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
6.1 mi from Santa Maria
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
$48 nightly
The price is $48
Feb 6 - Feb 7
Hotel La Ria Durán
Reception

Hostal California Inn

Hostal California Inn
3.0 star property
4.6 mi from Santa Maria
8.6 out of 10, Excellent, (8 reviews)
"Me encantó, es muy cómoda, la habitación super amplia y limpia Si duda volveré "
Mexico
Anita
Hostal California Inn
Comfort Apartment, Kitchenette

Guayacan Apart Hotel

Guayacan Apart Hotel
2.0 star property
Downtown Guayaquil, 4.7 mi from Santa Maria
$40 nightly
The price is $40
Feb 6 - Feb 7
Guayacan Apart Hotel
Terrace/patio

Hotel del Parque

Hotel del Parque
4.5 star property
4.4 mi from Santa Maria
9.8 out of 10, Exceptional, (111 reviews)
"Friendly staff. We arrived very early and they were ablemto accommodate an early check-in. The hotel is beautiful "
Canada
Victor
$305 nightly
The price is $336
Feb 6 - Feb 7
Hotel del Parque
Standard Double Room | Desk, free WiFi

Hostal Bicentenario

Hostal Bicentenario
2.0 star property
Downtown Guayaquil, 4.7 mi from Santa Maria
6.0 out of 10, (4 reviews)
"The gentleman that checked me and my family in was amazing. He helped me get my car parked in the designated parking area, got my wife hot water to wash our baby's bottles, printed up copies of receipts I needed for a U.S. Consulate interview and was a very nice and helpful to myself and my family."
United States
Matthew
Hostal Bicentenario
Superior Double Room, 2 Twin Beds | Free WiFi, bed sheets

Hotel GH Sander

Hotel GH Sander
3.0 star property
Rocafuerte, 4.5 mi from Santa Maria
8.6 out of 10, Excellent, (14 reviews)
"great property. i would definitely come back again every time i come to guayaquil"
United States
George
$27 nightly
The price is $27
Feb 18 - Feb 19
Hotel GH Sander
Outdoor pool

Tropical Inn

Tropical Inn
2.0 star property
5.7 mi from Santa Maria
8.2 out of 10, Very Good, (16 reviews)
"for the price was good"
United States
Rosa
Tropical Inn
Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers

Cedros Inn Boutique Hotel

Cedros Inn Boutique Hotel
3.5 star property
Urdesa, 2.9 mi from Santa Maria
8.6 out of 10, Excellent, (87 reviews)
"Its a small and beatiful hotel, good location, nice and modern with excelent service. its a very good choice"
United States
LIBARDO
$61 nightly
The price is $69
Feb 27 - Feb 28
Cedros Inn Boutique Hotel
Property entrance

Hotel Presidente Internacional

Hotel Presidente Internacional
3.5 star property
4.6 mi from Santa Maria
6.0 out of 10, (27 reviews)
"La ubicación es excelente. Cerca de todo "
Colombia
Myriam
$39 nightly
The price is $43
Mar 6 - Mar 7
Hotel Presidente Internacional
Suite, Jetted Tub | In-room safe, free WiFi, bed sheets

Hotel Varadero Internacional

Hotel Varadero Internacional
3.0 star property
Downtown Guayaquil, 4.1 mi from Santa Maria
8.0 out of 10, Very Good, (66 reviews)
"Overall a good place to stay and close to most destinations."
United States
Daniel
$45 nightly
The price is $46
Feb 18 - Feb 19
Hotel Varadero Internacional
Junior Suite, 1 Double Bed, Kitchenette | Premium bedding, free WiFi, bed sheets

San Francisco Apart Hotel

San Francisco Apart Hotel
3.0 star property
La Atarazana, 3.7 mi from Santa Maria
6.2 out of 10, (23 reviews)
"Receptionist was very helpful finding us delivery food on arrival."
United States
William
$34 nightly
The price is $35
Feb 8 - Feb 9
San Francisco Apart Hotel
Gym

Hotel Cityzen Guayaquil

Hotel Cityzen Guayaquil
3.0 star property
4.7 mi from Santa Maria
9.0 out of 10, Wonderful, (37 reviews)
"Was nice "
United States
Joe
$51 nightly
The price is $52
Feb 9 - Feb 10
Hotel Cityzen Guayaquil
Economy Triple Room | Free WiFi, bed sheets

Hotel Dorado

Hotel Dorado
2.0 star property
Olmedo, 5.1 mi from Santa Maria
8.8 out of 10, Excellent, (13 reviews)
"Great location! Great value "
United States
John
$17 nightly
The price is $17
Feb 21 - Feb 22
Hotel Dorado
Down comforters, desk, free WiFi, bed sheets

Hotel Las Peñas

Hotel Las Peñas
3.0 star property
Rocafuerte, 4.8 mi from Santa Maria
8.4 out of 10, Very Good, (105 reviews)
"The air conditioning was great and the location was very good."
United States
Rommel
$36 nightly
The price is $37
Feb 8 - Feb 9
Hotel Las Peñas
Exterior

La Fontana Hotel

La Fontana Hotel
2.5 star property
Downtown Guayaquil, 4.9 mi from Santa Maria
8.0 out of 10, Very Good, (110 reviews)
"Room was excellent, service was excellent, Safe, easy check in-check out"
United States
Abraham
$65 nightly
The price is $65
Feb 9 - Feb 10
La Fontana Hotel
Outdoor spa tub

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana, 4.6 mi from Santa Maria
9.4 out of 10, Exceptional, (104 reviews)
"The apartment was in a great location and very clean and well maintained."
United States
Rolando
$98 nightly
The price is $99
Feb 13 - Feb 14
Luxury Suites Riverfront GYE
Free daily buffet breakfast

Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 5 mi from Santa Maria
9.2 out of 10, Wonderful, (1,002 reviews)
"Great team and flawless check in. "
United States
Fabio
$65 nightly
The price is $74
Feb 13 - Feb 14
Unipark by Oro Verde Hotels
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

They are here because people started feeding them
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Vista panorámica de las favelas de cerro santa ana, guayaquil, ecuador

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Numa Pompilio Llona Street while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and Civic Center are some notable places to visit nearby.

Iguanas at Seminario Park (Iguanas Park) - Guayaquil, Ecuador

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Top Santa Maria Hotel Reviews

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

10/10 Excellent
"All was neat, it's all we expected, thank you"
Diana Ximena 1-night trip
Posted 4 days ago
TRYP by Wyndham Guayaquil Airport

Frequently asked questions

Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Maria.
How can I save on a Santa Maria hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Santa Maria hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Maria hotel?
Hotel prices in Santa Maria often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia