Santa Cruz

Seville

Santa Cruz
Santa Cruz
Santa Cruz
Santa Cruz
Santa Cruz
Wander through a maze of cobbled streets in one of Seville's most picturesque areas, an ancient neighborhood that's home to major landmarks and medieval buildings.

Santa Cruz is one of the oldest neighborhoods in the city. The former medieval Jewish quarter is known for its squares framed by orange trees, narrow streets that keep out the sun, whitewashed homes adorned by flower-filled balconies and Seville's main monuments, the cathedral and the Giralda. Visit Santa Cruz on foot and discover insights into its long and fascinating past.

Nestled in the heart of the neighborhood or barrio is the 15th-century Seville Cathedral, a massive gothic structure that is one of the largest churches in the world. Marvel at centuries-old frescoes that adorn chapels, visit the tomb of explorer Christopher Columbus and climb up the bell tower, the Giralda. This was the tallest building in the city for hundreds of years, and its oldest part is a minaret from the 12th century.

Then walk over to the 14th-century mudejar-style Royal Alcazar of Seville, which is still used by the Spanish royal family when they're in the city.

Meander down extremely narrow pedestrianized streets called kissing lanes because the houses on opposite sides are so close. The streets were designed like this to maximize shade. Pause to admire tiled patios of mansions and townhouses through their wrought-iron gates.

Visit the Casa Fabiola for its collection of paintings, sculptures and religious pieces. Adjoining this renaissance Sevillian palace is a section of the wall that encircled the old Jewish quarter.

Trace the history of Seville's Jewish community by studying the artifacts and information panels at the Centro de Interpretación Judería de Sevilla.

Unwind in one of the beautiful squares that dot the neighborhood, such as Plaza Doña Elvira with its fountain, tiled benches and orange trees. Enjoy more tranquil moments in the Jardines de Murillo, a peaceful oasis of flowerbeds, fountains, arbors and magnolia trees, among other species.

Find the Santa Cruz neighborhood in the historic center of the city and enjoy its charm, beauty and atmosphere as you stroll through the cobblestone streets.


Popular places to visit

Things to do


Santa Cruz Hotel Deals

Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
$94 nightly
The price is $103 total per night from Jun 2 to Jun 3
$103 total
Jun 2 - Jun 3
Total with taxes and fees
Book a stay at this family-friendly hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,004 reviews)
The breakfast buffet was excellent, the staff attentive and the air conditioned appropiate.

Reviewed on May 13, 2026

Hotel Murillo
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
$170 nightly
The price is $187 total per night from Jun 7 to Jun 8
$187 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this spa hotel in Seville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,010 reviews)
Full of character and history

Reviewed on May 14, 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
$170 nightly
The price is $187 total per night from Jun 1 to Jun 2
$187 total
Jun 1 - Jun 2
Total with taxes and fees
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the bar in ...
9.6/10 Exceptional! (1,199 reviews)
Very clean rooms and the staff was great!

Reviewed on May 13, 2026

Hotel Amadeus Sevilla
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
$644 nightly
The price is $709 total per night from May 17 to May 18
$709 total
May 17 - May 18
Total with taxes and fees
Book a stay at this luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (1,000 reviews)
Lovely room. Breakfast was amazing and the bar was great service. Food was the best at this hotel

Reviewed on May 3, 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
$209 nightly
The price is $229 total per night from Jun 7 to Jun 8
$229 total
Jun 7 - Jun 8
Total with taxes and fees
Stay at this hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.6/10 Exceptional! (1,178 reviews)
Clean, good breakfast and great location with immediate bars and restaurants on your doorstep.

Reviewed on May 14, 2026

Hotel Rey Alfonso X
Hotel Murillo Reinoso

Hotel Murillo Reinoso

2 out of 5
Lope de Rueda, 16 Seville Seville
$132 nightly
The price is $146 total per night from Jun 7 to Jun 8
$146 total
Jun 7 - Jun 8
Total with taxes and fees
Stay at this hotel in Seville. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the property condition ...
9.6/10 Exceptional! (120 reviews)
The place was sensational Central to everything that you need to do in Seville. From check in with Laura to check out cannot fault anyone or anything.

Reviewed on May 12, 2026

Hotel Murillo Reinoso
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santa Cruz

El Arenal

El Arenal

5/5(211 area reviews)

Located in Seville's historical center, El Arenal boasts the 13th-century Torre del Oro, Royal Shipyards, and La Real Maestranza bullring. Explore this vibrant area on the Guadalquivir river's east bank.

El Arenal
San Bartolomé

San Bartolomé

Travelers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.

San Bartolomé
Alfalfa

Alfalfa

Unique features of Alfalfa include the bars and historic sites. Make a stop by Salvador Plaza or Calle Sierpes while you're exploring the area.

Alfalfa
Historical Center

Historical Center

4.5/5(606 area reviews)

Casa de la Memoria Cultural Center and Calle Sierpes are a few top attractions in Historical Center. Hop around the city on the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out the area's fantastic nightlife, stunning cathedral, and popular shops.

Historical Center
La Florida

La Florida

The restaurants and shopping are a few reasons travelers visit La Florida. Want to see more of the surrounding area? Murillo Gardens and Pilate's House are a few top sights nearby.

La Florida
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San Bernardo

Even though there aren't top sights in San Bernardo, you can explore the larger area and take in top sights like Murillo Gardens. Jump on the metro at Prado San Sebastián Tram Stop to see more of the city.

San Bernardo


Santa Cruz

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