Find Vacation Homes in St. Charles County, MO from $132

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Vacation Homes in St. Charles County

Charming Escape in Grafton!

10.0 out of 10, Exceptional, (12)
"Great location, very nice, clean, with everything you need. I wish the weather would have been a little better. We would definitely stay again. "
Charming Escape in Grafton!

St. Charles 1860's Gem - Sleeps 6!

9.8 out of 10, Exceptional, (122)
"Perfect place to stay while we were in town for a show! "
$236 nightly
The price is $236
Oct 12 - Oct 13
Total with taxes and fees
St. Charles 1860's Gem - Sleeps 6!

Residence on the Roundabout

9.4 out of 10, Exceptional, (138)
"Very clean. Comfortable couch/beds"
Residence on the Roundabout

Stunning 1890's Home - Sleeps 8!

10.0 out of 10, Exceptional, (79)
"We loved this beautiful property. The host was great at communicating with us and took care of everything we needed to accommodate my family. We will be booking this property for our next stay!"
$367 nightly
The price is $375
Oct 15 - Oct 16
Total with taxes and fees
Stunning 1890's Home - Sleeps 8!

Convenience 2 Bedroom House to Explore All of St Louis

9.8 out of 10, Exceptional, (31)
"One night stay. Location convenient to downtown Clayton. "
$245 nightly
The price is $263
Oct 5 - Oct 6
Total with taxes and fees
Convenience 2 Bedroom House to Explore All of St Louis

Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway

9.6 out of 10, Exceptional, (50)
"This place was perfect for our visit to St Charles. We'll definitely book it again the next time we come to visit family"
$352 nightly
The price is $352
Oct 2 - Oct 3
Total with taxes and fees
Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway

Centrally located in the Tower Grove East neighborhood!

9.8 out of 10, Exceptional, (128)
"Great stay, comfortable furnishings, quiet street. "
$143 nightly
The price is $168
Oct 2 - Oct 3
Total with taxes and fees
Centrally located in the Tower Grove East neighborhood!

Escape the city to quiet and picturesque Golden Eagle, IL..

10.0 out of 10, Exceptional, (357)
"Loved the property. It was beautiful and peaceful. A great place for total relaxation. Hosts respond quickly to messages."
Escape the city to quiet and picturesque Golden Eagle, IL..

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

9.8 out of 10, Exceptional, (148)
"Very walkable to everything in The Hill area! "
$130 nightly
The price is $132
Oct 6 - Oct 7
Total with taxes and fees
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Farmhouse 80 Acres Rec Room Peddle Boat Lake Fishing Nature Trl 2 ml to Grafton

10.0 out of 10, Exceptional, (124)
"Could not have asked for a nicer place"
$263 nightly
The price is $278
Oct 3 - Oct 4
Total with taxes and fees
Farmhouse 80 Acres Rec Room Peddle Boat Lake Fishing Nature Trl 2 ml to Grafton

House in Dogtown walking distance to the Zoo and Restaurants

10.0 out of 10, Exceptional, (39)
"Loved the stay - highly recommended"
House in Dogtown walking distance to the Zoo and Restaurants

Madison House 1 -Walk to Main St

8.8 out of 10, Excellent, (13)
"Comfortable place to stay easy to find location close to everything in St Charles"
$219 nightly
The price is $247
Oct 5 - Oct 6
Total with taxes and fees
Madison House 1 -Walk to Main St

The Lewis & Clark Hangout

9.0 out of 10, Wonderful, (18)
"Very clean, great communication with the property owner and location was close to everything we wanted to do. We had a great time! "
$322 nightly
The price is $362
Oct 2 - Oct 3
Total with taxes and fees
The Lewis & Clark Hangout

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

9.6 out of 10, Exceptional, (66)
"Comfy beds, plenty of towels, good location."
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Entire Dogtown House near Zoo, Forest Park and Wash U

10.0 out of 10, Exceptional, (214)
"Great place to stay. Quiet area and close to activities. "
Entire Dogtown House near Zoo, Forest Park and Wash U

The Original Custom House!

9.8 out of 10, Exceptional, (31)
"Perfect little property to stay and visit Main Street! "
$359 nightly
The price is $395
Oct 2 - Oct 3
Total with taxes and fees
The Original Custom House!

Unique, Homey, & Spacious City Nest

9.4 out of 10, Exceptional, (19)
"We had a wonderful time at this great location. The hosts were amazing and our time there was awesome. "
Unique, Homey, & Spacious City Nest

Charming 3-bedroom house with WiFi, AC in the heart of St. Louis

2.0 star property
8.4 out of 10, Very Good, (22)
"This was a great location. Perfect for our small group of friends. Very clean, easy check in. Very old house but done well. Would recommend. "
$287 nightly
The price is $305
Oct 13 - Oct 14
Total with taxes and fees
Charming 3-bedroom house with WiFi, AC in the heart of St. Louis

STL Family Favorite Gem.Heart of The Hill: SLU,WashU, Forest Park,Yard,Arch,BJC

10.0 out of 10, Exceptional, (34)
"We loved staying here! The house is very well remodeled and adorable, and a perfect location. We love to cook, and the kitchen was beautiful and well stocked. We will definitely stay here again. "
STL Family Favorite Gem.Heart of The Hill: SLU,WashU, Forest Park,Yard,Arch,BJC

Downtown Boho Bungalow

10.0 out of 10, Exceptional, (42)
"It was a great place to call home for a few days. "
Downtown Boho Bungalow
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles County Hotel Reviews

Find out more about St. Charles County

Find out more about St. Charles County

Booking Tips to Find the Best St. Charles County Vacation Homes


How much does it cost to rent a vacation home in St. Charles County?

You can find incredible St. Charles County vacation homes for all types of budgets: between $132 and $395 per night. The more amenities the rental has, and its proximity to popular places, the higher the price.


What is the best time to stay in a vacation home in St. Charles County?

If you are looking for a great deal on your vacation home in St. Charles County, consider visiting in , when prices are usually cheaper.


How many vacation homes are available for rent in St. Charles County?

There are 677 rental houses to choose from for your trip. You’ll find holiday homes located throughout the city, near sightseeing spots, and close to local nature areas.


How do I find the best deal for a vacation home in St. Charles County?

Begin by entering your trip dates to see what type of St. Charles County rental houses are available. Use the map to zoom closer into the areas or zoom out to include more locations. Use the filters on the left side of your search results to narrow down by star rating, price, number of bedrooms, amenities, and more—Expedia makes it easy to score the best deal for your budget.


Why should I rent a vacation home in St. Charles County?

Booking St. Charles County vacation home rentals is the perfect way to spend a vacation because of the privacy, variety of amenities, and comfort you’ll have in your own space.


What amenities are available in a private vacation home?

When thinking about what you want in your St. Charles County rental house, dream big! Depending on your budget and the area, you’ll find amenities like a private pool, hot tub, free parking, fully-equipped kitchen, in-home washer and dryer, Wi-Fi, and a beautiful view or easy access to local sightseeing spots. You can even filter your search results by accessibility to ensure that everyone in your party will be comfortable.


Why should I book a vacation home with Expedia?

Expedia has some of the best selection and deals on available vacation homes in the area—and all in one place. We reward you with members points back on every booking and ensure you get the right accommodation for the best price. And you’ll save big when you bundle your travel together, like booking a car rental in St. Charles County along with your vacation property, into a St. Charles County vacation package.


Can I cancel my vacation home with Expedia?

Some accommodations are free to cancel and refundable if done so by a specific date, while others may be non-refundable. To make sure that you can get your money back on cancellations, use the “free cancellation” filter during your search. Contact our customer service portal if you need help.

St. Charles County Vacation Homes information

Number of reviews
1,672
Accommodation
677 Vacation Homes
Lowest Price
$132
Highest Price
$395

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