$211 Cheap American Airlines flights La Crosse (LSE) to Chicago (ORD)

Make use of the "Price (lowest to highest)" filter on Expedia to search for cheap American Airlines return flights from $327 from LSE to ORD. Affordable one-way options from $211 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable American Airlines flights from La Crosse Municipal Airport (LSE) to O'Hare Intl. Airport (ORD) one to three months prior to your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and itinerary, the ideal day to book a domestic flight is usually Sunday and the most expensive day tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The earliest flight from LSE to ORD with American Airlines departs at 6:00AM UTC-6. You'll land at 7:24AM UTC-6. The final American Airlines flight of the day leaves at 5:00PM UTC-6 and arrives at 6:18PM UTC-6. With around 20% fewer cancellations for departures before midday, setting off early is generally the wisest option.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.