$79 Cheap Flights from Islip (ISP) to Buffalo (BUF)

View $79 flight on Wed, Aug 20, 2025Opens in a new window

Popular airlines from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Islip to Buffalo (ISP-BUF)

Prices were available within the past 7 days and start at $79 for one-way flights and $157 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Thu, Oct 9 - Wed, Oct 15
ISP
Islip
BUF
Buffalo
$157 Roundtrip, found 1 day ago
$157
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Oct 9 from Islip to Buffalo, returning Wed, Oct 15, priced at $157 found 1 day ago
Southwest Airlines
Thu, Aug 14 - Mon, Aug 25
ISP
Islip
BUF
Buffalo
$162 Roundtrip, found 1 hour ago
$162
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Thu, Aug 14 from Islip to Buffalo, returning Mon, Aug 25, priced at $162 found 1 hour ago
Southwest Airlines
Mon, Aug 25 - Sat, Aug 30
ISP
Islip
BUF
Buffalo
$172 Roundtrip, found 1 day ago
$172
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Mon, Aug 25 from Islip to Buffalo, returning Sat, Aug 30, priced at $172 found 1 day ago
Southwest Airlines
Sat, Nov 15 - Mon, Nov 17
ISP
Islip
BUF
Buffalo
$174 Roundtrip, found 1 hour ago
$174
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Sat, Nov 15 from Islip to Buffalo, returning Mon, Nov 17, priced at $174 found 1 hour ago
Southwest Airlines
Sat, Oct 11 - Sat, Oct 18
ISP
Islip
BUF
Buffalo
$177 Roundtrip, found 20 hours ago
$177
Roundtrip
found 20 hours ago
Select Southwest Airlines flight, departing Sat, Oct 11 from Islip to Buffalo, returning Sat, Oct 18, priced at $177 found 20 hours ago
Southwest Airlines
Thu, Aug 21 - Fri, Aug 29
ISP
Islip
BUF
Buffalo
$179 Roundtrip, found 1 day ago
$179
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Aug 21 from Islip to Buffalo, returning Fri, Aug 29, priced at $179 found 1 day ago
Southwest Airlines
Thu, Aug 21 - Fri, Aug 29
ISP
Islip
BUF
Buffalo
$184 Roundtrip, found 1 day ago
$184
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Aug 21 from Islip to Buffalo, returning Fri, Aug 29, priced at $184 found 1 day ago
Southwest Airlines
Mon, Sep 1 - Fri, Sep 5
ISP
Islip
BUF
Buffalo
$189 Roundtrip, found 1 day ago
$189
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Mon, Sep 1 from Islip to Buffalo, returning Fri, Sep 5, priced at $189 found 1 day ago
Frontier Airlines
Sat, Jun 28 - Fri, Jul 11
ISP
Islip
BUF
Buffalo
$210 Roundtrip, found 4 days ago
$210
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, Jun 28 from Islip to Buffalo, returning Fri, Jul 11, priced at $210 found 4 days ago
JetBlue Airways
Fri, Oct 24 - Mon, Oct 27
ISP
Islip
BUF
Buffalo
$246 Roundtrip, found 20 hours ago
$246
Roundtrip
found 20 hours ago
Select JetBlue Airways flight, departing Fri, Oct 24 from Islip to Buffalo, returning Mon, Oct 27, priced at $246 found 20 hours ago
Flights from Islip (ISP) to Buffalo (BUF)
Origin airport
MacArthur
Destination airport
Buffalo Niagara Intl.
Airlines serving
Frontier Airlines, JetBlue Airways, Southwest Airlines
Roundtrip price
$156
Distance
325 mi

Islip to Buffalo Flights

The cheapest times to fly from Islip to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Islip to Buffalo are during the month of October. You can find some of the cheapest flights from Islip to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Islip to Buffalo

Sunday is one of the best days to book for cheap flights from Islip to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Islip to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Islip to Buffalo in 2025. You can also book with separate airlines for your outbound and return journeys, from $79 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Islip to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Islip to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF) cost?
Discover the latest flight deals from ISP to BUF by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from ISP to BUF?
The cheapest flights from ISP to BUF are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)?
Although Islip, NY (ISP-MacArthur) doesn't have any direct flights to Buffalo Niagara Intl. Airport (BUF), other airports have nonstop routes. Traveling from John F. Kennedy Intl. Airport (JFK) will get you to Buffalo without any layovers.
What is the cheapest airline that flies from ISP to BUF?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from ISP to BUF. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)?
You'll have to catch a flight with a layover when traveling from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from ISP to BUF?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)?
To arrive at Buffalo Niagara Intl. Airport (BUF) on schedule, choose a flight that leaves from MacArthur Airport (ISP) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF) last-minute?
Last-minute fares from ISP to BUF are usually more expensive. For the best rates, start looking for flights as soon as possible. That being said, if you can play around with your travel dates, you may land a cheap fare right before your journey.
Is it cheaper to book an ISP to BUF flight and hotel package?
You'll typically save money by booking an ISP to BUF flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After selecting your preferred accommodations and flights, you can add extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)?
In most instances, you can reschedule or cancel your ISP to BUF flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you need more details, go to our Customer Service portal.

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*Available to One Key members.