$120 Cheap Flights from Lyon (LYS) to Istanbul (IST)

View $120 flight on Mon, Dec 22, 2025Opens in a new window

Popular airlines from Saint-Exupery Airport (LYS) to Istanbul Airport (IST)

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Cheap Flights from Lyon to Istanbul (LYS-IST)

Prices were available within the past 7 days and start at $120 for one-way flights and $215 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Transavia France
Sun, May 24 - Wed, Jun 3
LYS
Lyon
IST
Istanbul
$215 Roundtrip, found 4 days ago
$215
Roundtrip
found 4 days ago
Select Transavia France flight, departing Sun, May 24 from Lyon to Istanbul, returning Wed, Jun 3, priced at $215 found 4 days ago
Lufthansa
Mon, Dec 8 - Sun, Dec 14
LYS
Lyon
IST
Istanbul
$220 Roundtrip, found 2 days ago
$220
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Mon, Dec 8 from Lyon to Istanbul, returning Sun, Dec 14, priced at $220 found 2 days ago
Vueling Airlines
Tue, Dec 2 - Wed, Dec 24
LYS
Lyon
IST
Istanbul
$256 Roundtrip, found 16 hours ago
$256
Roundtrip
found 16 hours ago
Select Vueling Airlines flight, departing Tue, Dec 2 from Lyon to Istanbul, returning Wed, Dec 24, priced at $256 found 16 hours ago
LOT-Polish Airlines
Fri, Nov 28 - Thu, Dec 11
LYS
Lyon
IST
Istanbul
$277 Roundtrip, found 3 days ago
$277
Roundtrip
found 3 days ago
Select LOT-Polish Airlines flight, departing Fri, Nov 28 from Lyon to Istanbul, returning Thu, Dec 11, priced at $277 found 3 days ago
Turkish Airlines
Fri, Dec 12 - Thu, Dec 25
LYS
Lyon
IST
Istanbul
$288 Roundtrip, found 3 days ago
$288
Roundtrip
found 3 days ago
Select Turkish Airlines flight, departing Fri, Dec 12 from Lyon to Istanbul, returning Thu, Dec 25, priced at $288 found 3 days ago
KLM
Sun, Dec 7 - Tue, Dec 23
LYS
Lyon
IST
Istanbul
$302 Roundtrip, found 3 days ago
$302
Roundtrip
found 3 days ago
Select KLM flight, departing Sun, Dec 7 from Lyon to Istanbul, returning Tue, Dec 23, priced at $302 found 3 days ago
KM Malta Airlines
Thu, Nov 20 - Thu, Nov 27
LYS
Lyon
IST
Istanbul
$381 Roundtrip, found 3 days ago
$381
Roundtrip
found 3 days ago
Select KM Malta Airlines flight, departing Thu, Nov 20 from Lyon to Istanbul, returning Thu, Nov 27, priced at $381 found 3 days ago
Iberia
Thu, Dec 11 - Tue, Dec 23
LYS
Lyon
IST
Istanbul
$504 Roundtrip, found 6 days ago
$504
Roundtrip
found 6 days ago
Select Iberia flight, departing Thu, Dec 11 from Lyon to Istanbul, returning Tue, Dec 23, priced at $504 found 6 days ago
British Airways
Wed, Jan 7 - Tue, Jan 13
LYS
Lyon
IST
Istanbul
$526 Roundtrip, found 1 day ago
$526
Roundtrip
found 1 day ago
Select British Airways flight, departing Wed, Jan 7 from Lyon to Istanbul, returning Tue, Jan 13, priced at $526 found 1 day ago
Air France
Mon, Dec 22 - Fri, Dec 26
LYS
Lyon
IST
Istanbul
$530 Roundtrip, found 23 hours ago
$530
Roundtrip
found 23 hours ago
Select Air France flight, departing Mon, Dec 22 from Lyon to Istanbul, returning Fri, Dec 26, priced at $530 found 23 hours ago

Find the cheapest month to fly from Lyon (LYS) to Istanbul (IST)

June is typically the cheapest month to fly

From $107 - $318 per traveler.

Frequently asked questions

How much does a flight from Saint-Exupery Airport (LYS) to Istanbul (IST) cost?
Grab a cheap one-way flight from $120 or cheap return flight from $215 from Saint-Exupery Airport (LYS) to Istanbul (IST) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Saint-Exupery Airport (LYS) to Istanbul (IST)?
Flying in May may help you find better deals, as it's the cheapest month for flights between LYS and IST. You'll usually find the lowest fares during off-peak months.
What is the cheapest airline that flies from Saint-Exupery Airport (LYS) to Istanbul (IST)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll fly you from LYS to IST. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Saint-Exupery Airport (LYS) to Istanbul (IST)?
Nonstop flights from Saint-Exupery Airport (LYS) to Istanbul (IST) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from LYS to IST?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Saint-Exupery Airport (LYS) to Istanbul (IST)?
To land at Istanbul (IST) on time, opt for a flight that takes off from Saint-Exupery Airport (LYS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Saint-Exupery Airport (LYS) to Istanbul (IST) last-minute?
Last-minute bookings from LYS to IST are generally more expensive. For the best prices, start looking for flights early. That being said, if your travel plans are flexible, you may find a cheap ticket right before your journey.
Can I cancel or change the date of my flight from Saint-Exupery Airport (LYS) to Istanbul (IST)?
If you booked your LYS to IST flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you'd like more information.

Travel information

Origin airport
Saint-Exupery
Destination airport
Istanbul
Airlines serving
Air France, British Airways, Iberia, KLM, LOT-Polish Airlines, Lufthansa, Turkish Airlines, Vueling Airlines
Roundtrip price
$214
Distance
1220 mi
Average flight time
4 hours 20 mins

Book with confidence

Lyon to Istanbul Flights

The cheapest times to fly from Lyon to Istanbul

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lyon to Istanbul are during the month of May. You can find some of the cheapest flights from Lyon to Istanbul with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lyon to Istanbul

Sunday is one of the best days to book for cheap flights from Lyon to Istanbul: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lyon to Istanbul

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lyon to Istanbul in 2025. You can also book with separate airlines for your outbound and return journeys, from $120 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lyon to Istanbul flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lyon to Istanbul airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Lyon to Istanbul Flights

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*Available to One Key members.