$435 Cheap Flights from Lyon (LYS) to Chicago (ORD)

View $435 flight on Sun, Dec 14, 2025Opens in a new window

Popular airlines from Saint-Exupery Airport (LYS) to Chicago O'Hare Intl. Airport (ORD)

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Cheap Flights from Lyon to Chicago (LYS-ORD)

Prices were available within the past 7 days and start at $435 for one-way flights and $526 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAP Portugal
Tue, Nov 4 - Sun, Nov 30
LYS
Lyon
ORD
Chicago
$526 Roundtrip, found 6 days ago
$526
Roundtrip
found 6 days ago
Select TAP Portugal flight, departing Tue, Nov 4 from Lyon to Chicago, returning Sun, Nov 30, priced at $526 found 6 days ago
Scandinavian Airlines
Wed, Nov 19 - Sat, Nov 29
LYS
Lyon
ORD
Chicago
$550 Roundtrip, found 5 days ago
$550
Roundtrip
found 5 days ago
Select Scandinavian Airlines flight, departing Wed, Nov 19 from Lyon to Chicago, returning Sat, Nov 29, priced at $550 found 5 days ago
Air Canada
Wed, Nov 19 - Sat, Nov 29
LYS
Lyon
ORD
Chicago
$568 Roundtrip, found 5 days ago
$568
Roundtrip
found 5 days ago
Select Air Canada flight, departing Wed, Nov 19 from Lyon to Chicago, returning Sat, Nov 29, priced at $568 found 5 days ago
Air Canada
Mon, Nov 10 - Sun, Nov 30
LYS
Lyon
ORD
Chicago
$570 Roundtrip, found 6 days ago
$570
Roundtrip
found 6 days ago
Select Air Canada flight, departing Mon, Nov 10 from Lyon to Chicago, returning Sun, Nov 30, priced at $570 found 6 days ago
Air Canada
Tue, Nov 4 - Sun, Nov 30
LYS
Lyon
ORD
Chicago
$576 Roundtrip, found 6 days ago
$576
Roundtrip
found 6 days ago
Select Air Canada flight, departing Tue, Nov 4 from Lyon to Chicago, returning Sun, Nov 30, priced at $576 found 6 days ago
British Airways
Mon, May 18 - Thu, Jun 4
LYS
Lyon
ORD
Chicago
$577 Roundtrip, found 18 hours ago
$577
Roundtrip
found 18 hours ago
Select British Airways flight, departing Mon, May 18 from Lyon to Chicago, returning Thu, Jun 4, priced at $577 found 18 hours ago
Air Canada
Wed, Nov 19 - Sun, Nov 23
LYS
Lyon
ORD
Chicago
$577 Roundtrip, found 5 days ago
$577
Roundtrip
found 5 days ago
Select Air Canada flight, departing Wed, Nov 19 from Lyon to Chicago, returning Sun, Nov 23, priced at $577 found 5 days ago
Scandinavian Airlines
Mon, Jan 12 - Thu, Jun 4
LYS
Lyon
ORD
Chicago
$585 Roundtrip, found 3 days ago
$585
Roundtrip
found 3 days ago
Select Scandinavian Airlines flight, departing Mon, Jan 12 from Lyon to Chicago, returning Thu, Jun 4, priced at $585 found 3 days ago
Lufthansa
Wed, Nov 19 - Sun, Nov 23
LYS
Lyon
ORD
Chicago
$600 Roundtrip, found 5 days ago
$600
Roundtrip
found 5 days ago
Select Lufthansa flight, departing Wed, Nov 19 from Lyon to Chicago, returning Sun, Nov 23, priced at $600 found 5 days ago
Brussels Airlines
Mon, Dec 8 - Mon, Dec 15
LYS
Lyon
ORD
Chicago
$629 Roundtrip, found 9 hours ago
$629
Roundtrip
found 9 hours ago
Select Brussels Airlines flight, departing Mon, Dec 8 from Lyon to Chicago, returning Mon, Dec 15, priced at $629 found 9 hours ago

Alternative airports near Chicago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to O'Hare Intl. ORD. Cheapest option available. Average driving time to city center is 23 minutes. Flights from $623
ORD
O'Hare Intl.
Cheapest
Average driving time to city center23 min
Flights from $623

Frequently asked questions

How much does a flight from Saint-Exupery Airport (LYS) to O'Hare Intl. Airport (ORD) cost?
Snag a cheap one-way flight from $435 or cheap return flight from $526 from Saint-Exupery Airport (LYS) to O'Hare Intl. Airport (ORD) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Saint-Exupery Airport (LYS) to O'Hare Intl. Airport (ORD)?
The cheapest month to fly from LYS to ORD is November, when there's less demand. Off-peak season is generally when better flight deals are available between these airports.
What is the cheapest airline that flies from Saint-Exupery Airport (LYS) to O'Hare Intl. Airport (ORD)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll fly you from LYS to ORD. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from Saint-Exupery Airport (LYS) to O'Hare Intl. Airport (ORD)?
You'll need to catch a flight with a layover if you're traveling from Saint-Exupery Airport (LYS) to O'Hare Intl. Airport (ORD). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from LYS to ORD?
Usually you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can vary based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Saint-Exupery Airport (LYS) to O'Hare Intl. Airport (ORD)?
Opt for a flight from Saint-Exupery Airport (LYS) to O'Hare Intl. Airport (ORD) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Saint-Exupery Airport (LYS) to O'Hare Intl. Airport (ORD) last-minute?
Last-minute bookings from LYS to ORD are generally more expensive. For the lowest rates, start searching for flights as soon as possible. That being said, if you can play around with your travel dates, it's possible to land a cheap ticket right before you leave.
Is it cheaper to book a LYS to ORD flight and hotel package?
You'll generally save money by booking a LYS to ORD flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. After selecting your ideal accommodations and flights, consider adding extras like car rentals, tours and activities.
Can I cancel or change the date of my flight from Saint-Exupery Airport (LYS) to O'Hare Intl. Airport (ORD)?
You can usually cancel or reschedule your LYS to ORD flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Saint-Exupery
Destination airport
O'Hare Intl.
Airlines serving
Aer Lingus, Air Canada, Austrian Airlines, British Airways, Brussels Airlines, Iberia, LOT-Polish Airlines, Lufthansa, Scandinavian Airlines, TAP Portugal, Turkish Airlines
Roundtrip price
$526
Distance
4362 mi

Book with confidence

Lyon to Chicago Flights

The cheapest times to fly from Lyon to Chicago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lyon to Chicago are during the month of November. You can find some of the cheapest flights from Lyon to Chicago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lyon to Chicago

Sunday is one of the best days to book for cheap flights from Lyon to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lyon to Chicago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lyon to Chicago in 2025. You can also book with separate airlines for your outbound and return journeys, from $435 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lyon to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lyon to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Lyon to Chicago Flights

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*Available to One Key members.