$317 Cheap Flights from Medellín (MDE) to Islip (ISP)

View $317 flight on Wed, Nov 19, 2025Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Medellín to Islip (MDE-ISP)

Prices were available within the past 7 days and start at $317 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Flights from Medellín (MDE) to Islip (ISP)
Origin airport
José María Córdova Intl.
Destination airport
MacArthur
Distance
2396 mi

Medellín to Islip Flights

The cheapest times to fly from Medellín to Islip

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Islip are during the month of . You can find some of the cheapest flights from Medellín to Islip with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Islip

Sunday is one of the best days to book for cheap flights from Medellín to Islip: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Islip

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Islip in 2025. You can also book with separate airlines for your outbound and return journeys, from $317 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Islip flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Islip airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP) cost?
Snag a cheap one-way flight from $317 or cheap return flight from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP)?
The cheapest month to fly from MDE to ISP is , when there's less demand. Off-peak months are often when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP)?
To find the cheapest airline that'll fly you from MDE to ISP, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP)?
There are no daily direct flights available from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from MDE to ISP?
Usually you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* But this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP)?
Choose a flight from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP) that leaves before 3 PM to reduce the risk of cancellations. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Islip from Jose Maria Cordova Intl. Airport (MDE)?
Explore your flight options from Jose Maria Cordova Intl. Airport (MDE) to John F. Kennedy Intl. Airport (JFK). This is the only Islip airport you can land at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP) last-minute?
Last-minute fares from MDE to ISP are usually more expensive. To lock in the lowest prices, start searching for flights well in advance. That said, if you're flexible with your travel dates, it's possible to score a cheap ticket right before your journey.
Is it cheaper to book a MDE to ISP flight and hotel package?
Compared with arranging hotels and flights separately, booking a MDE to ISP flight and hotel package with Expedia could result in significant savings. Better still, having everything in one easy place will take the stress out of travel planning. Simply pick your flights and choose from our wide range of stays, then tailor your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to MacArthur Airport (ISP)?
If you reserved your MDE to ISP flight in the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.

Explore a world of travel with Expedia

*Available to One Key members.