$399 Cheap Flights from Myrtle Beach (MYR) to Brussels (BRU)

View $399 flight on Mon, Jan 12, 2026Opens in a new window

Popular airlines from Myrtle Beach to Brussels

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Cheap Flights from Myrtle Beach to Brussels (MYR-BRU)

Prices were available within the past 7 days and start at $399 for one-way flights and $479 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Tue, Jan 27 - Tue, Feb 3
MYR
Myrtle Beach
BRU
Brussels
$479 Roundtrip, found 4 days ago
$479
Roundtrip
found 4 days ago
Select Air Canada flight, departing Tue, Jan 27 from Myrtle Beach to Brussels, returning Tue, Feb 3, priced at $479 found 4 days ago
Air Canada
Tue, Jan 27 - Tue, Feb 3
MYR
Myrtle Beach
BRU
Brussels
$491 Roundtrip, found 4 days ago
$491
Roundtrip
found 4 days ago
Select Air Canada flight, departing Tue, Jan 27 from Myrtle Beach to Brussels, returning Tue, Feb 3, priced at $491 found 4 days ago
Air Canada
Tue, Jan 27 - Tue, Feb 3
MYR
Myrtle Beach
BRU
Brussels
$502 Roundtrip, found 4 days ago
$502
Roundtrip
found 4 days ago
Select Air Canada flight, departing Tue, Jan 27 from Myrtle Beach to Brussels, returning Tue, Feb 3, priced at $502 found 4 days ago
Air Canada
Tue, Jan 27 - Tue, Feb 3
MYR
Myrtle Beach
BRU
Brussels
$514 Roundtrip, found 4 days ago
$514
Roundtrip
found 4 days ago
Select Air Canada flight, departing Tue, Jan 27 from Myrtle Beach to Brussels, returning Tue, Feb 3, priced at $514 found 4 days ago
American Airlines
Sun, Feb 1 - Sun, Feb 8
MYR
Myrtle Beach
BRU
Brussels
$523 Roundtrip, found 2 days ago
$523
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Feb 1 from Myrtle Beach to Brussels, returning Sun, Feb 8, priced at $523 found 2 days ago
Delta
Sun, Feb 1 - Sun, Feb 8
MYR
Myrtle Beach
BRU
Brussels
$528 Roundtrip, found 2 days ago
$528
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Feb 1 from Myrtle Beach to Brussels, returning Sun, Feb 8, priced at $528 found 2 days ago
Delta
Sun, Feb 1 - Sun, Feb 8
MYR
Myrtle Beach
BRU
Brussels
$556 Roundtrip, found 2 days ago
$556
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Feb 1 from Myrtle Beach to Brussels, returning Sun, Feb 8, priced at $556 found 2 days ago
KLM
Sun, Feb 1 - Sun, Feb 8
MYR
Myrtle Beach
BRU
Brussels
$584 Roundtrip, found 2 days ago
$584
Roundtrip
found 2 days ago
Select KLM flight, departing Sun, Feb 1 from Myrtle Beach to Brussels, returning Sun, Feb 8, priced at $584 found 2 days ago
Delta
Sun, Feb 1 - Sun, Feb 8
MYR
Myrtle Beach
BRU
Brussels
$612 Roundtrip, found 2 days ago
$612
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Feb 1 from Myrtle Beach to Brussels, returning Sun, Feb 8, priced at $612 found 2 days ago
British Airways
Mon, Mar 16 - Tue, Mar 24
MYR
Myrtle Beach
BRU
Brussels
$724 Roundtrip, found 6 days ago
$724
Roundtrip
found 6 days ago
Select British Airways flight, departing Mon, Mar 16 from Myrtle Beach to Brussels, returning Tue, Mar 24, priced at $724 found 6 days ago

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Brussels - National Airport (BRU) cost?
Get a cheap one-way flight from $399 or cheap return flight from $479 from Myrtle Beach Intl. Airport (MYR) to Brussels - National Airport (BRU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to Brussels - National Airport (BRU)?
Traveling in January can help you save, as it's the cheapest month for flights between MYR and BRU. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to Brussels - National Airport (BRU)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from MYR to BRU. Then, sort your results by "Price (lowest to highest)" to snap up a good deal.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Brussels - National Airport (BRU)?
There aren't any daily nonstop flights available from Myrtle Beach Intl. Airport (MYR) to Brussels - National Airport (BRU). But you can choose flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be on your way in no time.
What day of the week has the most flights from MYR to BRU?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Brussels - National Airport (BRU)?
To arrive at Brussels - National Airport (BRU) on schedule, select a flight that leaves from Myrtle Beach Intl. Airport (MYR) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Brussels - National Airport (BRU) last-minute?
Holding off until right before your break to book a ticket from MYR to BRU often results in higher prices. While you might find some last-minute discounts, they aren't always guaranteed. Be flexible with your travel plans for the best chance of getting a bargain.
Is it cheaper to book a MYR to BRU flight and hotel package?
You'll generally save money by securing a MYR to BRU flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. After selecting your ideal accommodations and flights, you can add extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Brussels - National Airport (BRU)?
Typically, you're able to reschedule or cancel your MYR to BRU flight. However, there may be additional charges, especially if you booked more than 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you want further details, visit our Customer Service portal.

Travel information

Origin airport
Myrtle Beach Intl.
Destination airport
Brussels - National
Airlines serving
Air Canada, British Airways, Scandinavian Airlines
Roundtrip price
$478
Distance
4188 mi

Book with confidence

Myrtle Beach to Brussels Flights

The cheapest times to fly from Myrtle Beach to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Brussels are during the month of January. You can find some of the cheapest flights from Myrtle Beach to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Brussels

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Brussels in 2026. You can also book with separate airlines for your outbound and return journeys, from $399 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Myrtle Beach to Brussels Flights

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*Available to One Key members.