$619 Cheap Flights from Prague (PRG) to Santiago (SCL)

View $619 flight on Tue, Jan 13, 2026Opens in a new window

Popular airlines from Vaclav Havel Airport (PRG) to Santiago Intl. Airport (SCL)

Cheap Flights from Prague to Santiago (PRG-SCL)

Prices were available within the past 7 days and start at $619 for one-way flights and $937 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Thu, Jan 29 - Thu, Feb 19
PRG
Prague
SCL
Santiago
$937 Roundtrip, found 5 days ago
$937
Roundtrip
found 5 days ago
Select United flight, departing Thu, Jan 29 from Prague to Santiago, returning Thu, Feb 19, priced at $937 found 5 days ago
United
Thu, Jan 29 - Fri, Feb 13
PRG
Prague
SCL
Santiago
$960 Roundtrip, found 5 days ago
$960
Roundtrip
found 5 days ago
Select United flight, departing Thu, Jan 29 from Prague to Santiago, returning Fri, Feb 13, priced at $960 found 5 days ago
United
Mon, Mar 2 - Tue, Mar 17
PRG
Prague
SCL
Santiago
$983 Roundtrip, found 5 days ago
$983
Roundtrip
found 5 days ago
Select United flight, departing Mon, Mar 2 from Prague to Santiago, returning Tue, Mar 17, priced at $983 found 5 days ago
United
Mon, Feb 9 - Fri, Feb 20
PRG
Prague
SCL
Santiago
$998 Roundtrip, found 5 days ago
$998
Roundtrip
found 5 days ago
Select United flight, departing Mon, Feb 9 from Prague to Santiago, returning Fri, Feb 20, priced at $998 found 5 days ago
Air Canada
Thu, Jan 15 - Mon, Jan 26
PRG
Prague
SCL
Santiago
$1,003 Roundtrip, just found
$1,003
Roundtrip
just found
Select Air Canada flight, departing Thu, Jan 15 from Prague to Santiago, returning Mon, Jan 26, priced at $1,003 just found
United
Sun, Mar 1 - Tue, Mar 17
PRG
Prague
SCL
Santiago
$1,003 Roundtrip, found 5 days ago
$1,003
Roundtrip
found 5 days ago
Select United flight, departing Sun, Mar 1 from Prague to Santiago, returning Tue, Mar 17, priced at $1,003 found 5 days ago
United
Mon, Mar 2 - Mon, Mar 16
PRG
Prague
SCL
Santiago
$1,005 Roundtrip, found 5 days ago
$1,005
Roundtrip
found 5 days ago
Select United flight, departing Mon, Mar 2 from Prague to Santiago, returning Mon, Mar 16, priced at $1,005 found 5 days ago
Turkish Airlines
Thu, Jan 1 - Tue, Jan 20
PRG
Prague
SCL
Santiago
$1,142 Roundtrip, found 5 days ago
$1,142
Roundtrip
found 5 days ago
Select Turkish Airlines flight, departing Thu, Jan 1 from Prague to Santiago, returning Tue, Jan 20, priced at $1,142 found 5 days ago
American Airlines
Wed, Feb 4 - Sat, Feb 21
PRG
Prague
SCL
Santiago
$1,158 Roundtrip, found 5 days ago
$1,158
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Feb 4 from Prague to Santiago, returning Sat, Feb 21, priced at $1,158 found 5 days ago
Delta
Fri, Oct 10 - Thu, Oct 16
PRG
Prague
SCL
Santiago
$1,376 Roundtrip, found 5 days ago
$1,376
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Oct 10 from Prague to Santiago, returning Thu, Oct 16, priced at $1,376 found 5 days ago

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $1,462
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $1,462

Frequently asked questions

How much does a flight from Vaclav Havel Airport (PRG) to Arturo Merino Benitez Airport (SCL) cost?
Get a cheap one-way flight from $619 or cheap return flight from $937 from Vaclav Havel Airport (PRG) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Vaclav Havel Airport (PRG) to Arturo Merino Benitez Airport (SCL)?
Traveling in January is a great way to save, as it's the cheapest month for flights between PRG and SCL. You'll often find the lowest prices during off-peak months.
What is the cheapest airline that flies from Vaclav Havel Airport (PRG) to Arturo Merino Benitez Airport (SCL)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest PRG to SCL flight.
How many flights per day from Vaclav Havel Airport (PRG) to Arturo Merino Benitez Airport (SCL)?
There aren't any daily direct flights available from Vaclav Havel Airport (PRG) to Arturo Merino Benitez Airport (SCL). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way in no time.
What day of the week has the most flights from PRG to SCL?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can change depending on various factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Vaclav Havel Airport (PRG) to Arturo Merino Benitez Airport (SCL)?
To avoid potential delays on the Vaclav Havel Airport (PRG) to Arturo Merino Benitez Airport (SCL) route, travel before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Vaclav Havel Airport (PRG) to Arturo Merino Benitez Airport (SCL) last-minute?
Last-minute fares from PRG to SCL are typically more expensive. To secure the best prices, start searching for flights as soon as possible. That said, if your travel plans are flexible, it's possible to score a cheap fare right before you leave.
Is it cheaper to book a PRG to SCL flight and hotel package?
You'll typically save money by securing a PRG to SCL flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. Once you've chosen your preferred accommodations and flights, consider adding extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Vaclav Havel Airport (PRG) to Arturo Merino Benitez Airport (SCL)?
It's usually possible to cancel or reschedule your PRG to SCL flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Travel information

Origin airport
Vaclav Havel
Destination airport
Arturo Merino Benitez
Airlines serving
Air France, American Airlines, British Airways, Delta, Iberia, KLM, LATAM Airlines Group, Turkish Airlines
Roundtrip price
$936
Distance
7745 mi

Book with confidence

Book with confidence

Prague to Santiago Flights

The cheapest times to fly from Prague to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Prague to Santiago are during the month of January. You can find some of the cheapest flights from Prague to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Prague to Santiago

Sunday is one of the best days to book for cheap flights from Prague to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Prague to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Prague to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $619 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Prague to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Prague to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Prague to Santiago Flights

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*Available to One Key members.