$463 Cheap Flights from Pisa (PSA) to Buffalo (BUF)

View $463 flight on Thu, Nov 20, 2025Opens in a new window

Popular airlines from Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Pisa to Buffalo (PSA-BUF)

Prices were available within the past 7 days and start at $463 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF) cost?
Lock in a cheap one-way flight from $463 or cheap return flight from Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF)?
Planning your trip for is a great way to save, as it's the cheapest month for flights between PSA and BUF. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF)?
To find the cheapest airline that'll fly you from PSA to BUF, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF)?
You'll need to book a flight with a layover if you're traveling from Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from PSA to BUF?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF)?
To avoid possible delays on the Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF) route, fly before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF) last-minute?
Last-minute fares from PSA to BUF are usually more expensive. For the cheapest rates, start searching for flights well ahead of time. That being said, if you can play around with your travel dates, you may land a cheap ticket right before your journey.
Is it cheaper to book a PSA to BUF flight and hotel package?
Opting for a PSA to BUF flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our impressive range of hotels and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Galileo Galilei Airport (PSA) to Buffalo Niagara Intl. Airport (BUF)?
It's generally possible to cancel or reschedule your PSA to BUF flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Travel information

Origin airport
Galileo Galilei
Destination airport
Buffalo Niagara Intl.
Distance
4242 mi

Book with confidence

Book with confidence

Pisa to Buffalo Flights

The cheapest times to fly from Pisa to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pisa to Buffalo are during the month of . You can find some of the cheapest flights from Pisa to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pisa to Buffalo

Sunday is one of the best days to book for cheap flights from Pisa to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pisa to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pisa to Buffalo in 2025. You can also book with separate airlines for your outbound and return journeys, from $463 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pisa to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pisa to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Pisa to Buffalo Flights

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*Available to One Key members.