Uptown, CO

Denver

A nighttime aerial view of a densely populated city with illuminated streets and buildings.
A cityscape with a mix of modern and older buildings, a prominent white building with a blue sign, and a clear view of distant mountains.
An aerial view of a densely populated urban area with a mix of residential and commercial buildings, a prominent church, and a distant city skyline.
A cityscape with modern high-rise buildings, a mix of residential and commercial structures, and a clear blue sky.
A cityscape with tall buildings, a church, and a busy intersection.

Stay near popular Uptown attractions

Cathedral of the Immaculate Conception

After visiting Cathedral of the Immaculate Conception, make a plan to see the other sights and activities in Denver. Amble around this vibrant area's picturesque gardens or experience its acclaimed theater scene.
See properties

Things to do

Denver: Meow Wolf's Convergence Station Admission Ticket

Denver: Meow Wolf Convergence Station Ticket

$50
per adult
92% of travellers recommend
Denver: Meow Wolf Convergence Station Ticket
General Admission to Denver Botanic Gardens Ticket

General Admission to Denver Botanic Gardens Ticket

$18
per adult
96% of travellers recommend
General Admission to Denver Botanic Gardens Ticket
Rocky Mountain Escape

Rocky Mountain Escape

$99
per traveler
96% of travellers recommend
Rocky Mountain Escape
Denver: Get High on a Mountain Tour with Sunset Views

Denver: Get High on a Mountain Tour with Sunset Views

$89
per adult
86% of travellers recommend
Denver: Get High on a Mountain Tour with Sunset Views
Denver: Puff Pass and Painting Class

Denver: Puff Pass and Painting Class

$39
per adult
100% of travellers recommend
Denver: Puff Pass and Painting Class
Denver: Museum of Nature and Science Entry Ticket

Denver: Museum of Nature and Science Entry Ticket

$26
per adult
84% of travellers recommend
Denver: Museum of Nature and Science Entry Ticket
See all activities in Denver

Uptown Hotel Deals

Hampton Inn & Suites Denver-Downtown

Hampton Inn & Suites Denver-Downtown

3 out of 5
1845 Sherman St Denver CO
$104 nightly
The price is $120 total per night from Sep 7 to Sep 8
$120 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Denver. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (2,169 reviews)
"The room was ok but the bathroom sink drained very slowly and the faucet handle was broken I could turn the water on and off but never had hot water. Also the parking situation was terrible. There weee two lots next to the hotel but they had strange hours and there was parking on the street with ..."

Reviewed on Aug 30, 2026

Hampton Inn & Suites Denver-Downtown
Warwick Denver

Warwick Denver

4 out of 5
1776 Grant Street Denver CO
$148 nightly
The price is $171 total per night from Sep 7 to Sep 8
$171 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Denver. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the pool and ...
8.6/10 Excellent! (2,019 reviews)
"Love the rooftop pool! Room was spacious."

Reviewed on Aug 31, 2026

Warwick Denver
Hyatt Place Peña Station/Denver Airport

Hyatt Place Peña Station/Denver Airport

3 out of 5
6110 NORTH PANASONIC WAY Denver CO
$88 nightly
The price is $101 total per night from Oct 1 to Oct 2
$101 total
Oct 1 - Oct 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Denver. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the restaurant ...
9/10 Wonderful! (3,302 reviews)
"Good stay i was in and out so short time but ery good."

Reviewed on Aug 31, 2026

Hyatt Place Peña Station/Denver Airport
Sonesta Denver Downtown

Sonesta Denver Downtown

4 out of 5
1450 Glenarm Place Denver CO
$107 nightly
The price is $124 total per night from Sep 8 to Sep 9
$124 total
Sep 8 - Sep 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Denver. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.6/10 Excellent! (2,733 reviews)
"Room was clean, got maintained every day. AC blew nice and cold my whole trip. I had it set that way. Breakfast buffet is only worth it if it's included with your stay. I would not recommend paying for it"

Reviewed on Aug 31, 2026

Sonesta Denver Downtown
Renaissance Denver Hotel & Conference Center

Renaissance Denver Hotel & Conference Center

4 out of 5
3801 Quebec St Denver CO
$118 nightly
The price is $137 total per night from Sep 13 to Sep 14
$137 total
Sep 13 - Sep 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Denver. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,832 reviews)
"The hotel was amazing! From check in to check out the staff were all so friendly and helpful. The Skyhawk Bar & Lounge has delicious food and the drinks were perfect. The swimming pools were both very clean and warm enough to enjoy swimming. The arcade was a fun surprise. The only negative experience ..."

Reviewed on Aug 31, 2026

Renaissance Denver Hotel & Conference Center
Hyatt Centric Downtown Denver

Hyatt Centric Downtown Denver

4 out of 5
1776 Champa St Denver CO
$123 nightly
The price is $142 total per night from Sep 7 to Sep 8
$142 total
Sep 7 - Sep 8
Total with taxes and fees
Stay at this hotel in Denver. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in our reviews. ...
Hyatt Centric Downtown Denver
See all 4,930 properties in Uptown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Uptown

Find the best Uptown areas and neighborhoods for the activities you enjoy most. Learn more about Uptown
Learn more about Uptown
A modern architectural complex with geometric shapes and a prominent red sculpture.

Downtown Denver

Enjoy the popular shops in Downtown Denver. Paramount Theater is a worthwhile stop, and you can jump on the metro at 16th - California Station or 16th - Stout Station to see more of Denver.

A city street with a large canopy structure, modern buildings, and potted plants.

Cherry Creek

Abundant dining options and stunning river views are well-reviewed features of Cherry Creek. Make a stop by top sights like Cherry Creek Shopping Center while you're exploring the area.

A brightly lit train station with a large Christmas tree and illuminated decorations.

LoDo

Take time in LoDo to visit attractions like Union Station and McGregor Square. You might also appreciate the abundant dining options, and you can hop on the metro at Union Station-Coors Field-16th St. Mall Station to see more of the city.

A cityscape with modern buildings and a forested area in the foreground.

Denver Tech Center

Known for its ample dining options and great live music, there's plenty to explore in Denver Tech Center. You can visit top attractions like Fiddler's Green Amphitheatre and The Landmark Theatre Greenwood Village, and jump on the metro at Orchard Station or Arapahoe at Village Center Station to see more of the city.

A large building with a dome, surrounded by a well-maintained garden with various flowers.

Capitol Hill

Unique features of Capitol Hill include the museums and bars. Make a stop by Molly Brown House Museum or Colorado State Capitol Building while you're exploring the area.

Uptown, CO

Choose one or more items to build your trip:

Explore a world of travel with Expedia