Find 4 Star Hotels in Cross Keys, MO from $111
Check availability on Cross Keys 4 Star Hotels
Compare Cross Keys 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Downtown St. Louis
8.8 out of 10, Excellent, (1146)
"Really nice hotel!"
DARIN
$101 nightly
The price is $120
Dec 8 - Dec 9
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
Downtown St. Louis
8.4 out of 10, Very Good, (3999)
"Loved our stay. Great location and awesome view from room "
Phillip
$95 nightly
The price is $111
Dec 21 - Dec 22
Total with taxes and fees
Hilton St. Louis Frontenac
Frontenac
8.8 out of 10, Excellent, (1002)
"Very nice hotel. Friendly and helpful staff. "
Andrew
$130 nightly
The price is $152
Dec 14 - Dec 15
Total with taxes and fees
21C Museum Hotel St Louis
Downtown West
9.0 out of 10, Wonderful, (1481)
"Great staff and clean room"
Chris
$131 nightly
The price is $153
Dec 28 - Dec 29
Total with taxes and fees
The Cheshire
Richmond Heights
8.6 out of 10, Excellent, (1000)
"Excellent place to stay. "
Todd
$129 nightly
The price is $153
Dec 7 - Dec 8
Total with taxes and fees
Renaissance St. Louis Airport Hotel
Berkeley
8.4 out of 10, Very Good, (1045)
"Staff was courteous and the room was clean."
Mia
$118 nightly
The price is $138
Dec 19 - Dec 20
Total with taxes and fees
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
8.8 out of 10, Excellent, (1032)
"This was a wonderful first experience at a beautiful hotel with such friendly staff. We will definitely stay here again!"
Alexis
$119 nightly
The price is $141
Dec 11 - Dec 12
Total with taxes and fees
Live by Loews - St.Louis
Downtown St. Louis
9.4 out of 10, Exceptional, (1096)
"We had an amazing view of the ballpark! The room and service was great. The restaurant and food room service were delicious!
Overall great stay!"
Melissa
$149 nightly
The price is $177
Dec 7 - Dec 8
Total with taxes and fees
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Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Cross Keys.
Four Seasons Hotel St Louis
999 North Second Street St. Louis MO
$415 nightly
The price is $485 total per night from Jan 1 to Jan 2
$485 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
9.4/10 Exceptional! (1,006 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Cross Keys Hotel Reviews
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
10/10 Excellent
Find out more about Cross Keys
Cross Keys Four Star Hotel Information
When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Cross Keys, St. Louis are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Cross Keys 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.
Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Cross Keys. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Cross Keys, St. Louis, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.
Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Cross Keys hotels offer everything your heart desires.
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