Find hotels in Cross Keys, MO from $66

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Dec 25 - Dec 26
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Our top choices for Cross Keys hotels

Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very Good, (4023)
"Everything was great!"
United States
Kathryn
$99 nightly
The price is $117
Dec 30 - Dec 31
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
Exterior
Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
Troy
9.4 out of 10, Exceptional, (711)
"Room spotless staff friendly "
United States
Allen
$93 nightly
The price is $103
Jan 11 - Jan 12, 2026
Total with taxes and fees
Holiday Inn Express Troy by IHG
Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1108)
"Clean room, great restaurant and bar down stairs "
United States
Ambria
$149 nightly
The price is $177
Dec 25 - Dec 26
Total with taxes and fees
Live by Loews - St.Louis
Casino
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1000)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
$166 nightly
The price is $194
Dec 25 - Dec 26
Total with taxes and fees
Ameristar Casino Resort and Spa
Lobby sitting area
Missouri Athletic Club

Missouri Athletic Club

Missouri Athletic Club
3.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1000)
"The room was nice and the staff was excellent."
United States
Annette
$134 nightly
The price is $157
Dec 25 - Dec 26
Total with taxes and fees
Missouri Athletic Club
Lounge
The Westin St. Louis

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1003)
"Great location "
United States
Gregory
$127 nightly
The price is $148
Dec 30 - Dec 31
Total with taxes and fees
The Westin St. Louis
Lobby
Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
St. Charles
8.6 out of 10, Excellent, (772)
"Great hotel! "
United States
Royally
$100 nightly
The price is $116
Dec 28 - Dec 29
Total with taxes and fees
Tru by Hilton St. Charles St. Louis, MO
Indoor pool, open 6:00 AM to 10:00 PM, sun loungers
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1182)
"Breakfast was great and this was my seventh year staying there."
United States
Derick
$98 nightly
The price is $114
Dec 30 - Dec 31
Total with taxes and fees
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Exterior
Courtyard by Marriott St. Louis West County

Courtyard by Marriott St. Louis West County

Courtyard by Marriott St. Louis West County
3.0 star property
Town and Country
9.0 out of 10, Wonderful, (453)
"Very nice place to stay. "
United States
John
$131 nightly
The price is $151
Jan 1 - Jan 2, 2026
Total with taxes and fees
Courtyard by Marriott St. Louis West County
Lobby
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1006)
"Breakfast was excellent along with clean comfortable beds. "
United States
Scott
$122 nightly
The price is $140
Jan 4 - Jan 5, 2026
Total with taxes and fees
Embassy Suites by Hilton St. Louis St. Charles
Lobby
Red Roof Inn St Louis - Troy, IL

Red Roof Inn St Louis - Troy, IL

Red Roof Inn St Louis - Troy, IL
2.0 star property
Troy
7.8 out of 10, Good, (1004)
"it was very good place to stay"
United States
Kent
$68 nightly
The price is $75
Dec 30 - Dec 31
Total with taxes and fees
Red Roof Inn St Louis - Troy, IL
Free daily buffet breakfast
Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
Edwardsville
9.2 out of 10, Wonderful, (821)
"Always a good stay here!"
United States
Chelsie
$116 nightly
The price is $133
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express & Suites Edwardsville by IHG
Free daily buffet breakfast
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1001)
"Everything was great!"
United States
Rita
$116 nightly
The price is $134
Jan 18 - Jan 19, 2026
Total with taxes and fees
Country Inn & Suites by Radisson, St. Charles Historic District
Lobby
Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center
3.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1054)
"It was perfect for our stay in St. Louis to visit the arch."
United States
Jacob
$94 nightly
The price is $110
Dec 29 - Dec 30
Total with taxes and fees
Pear Tree Inn St. Louis Convention Center
Exterior
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1018)
"My second time staying there as always it was lovely "
United States
Nina
$107 nightly
The price is $126
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hilton Pennywell St. Louis at the Arch
Lobby lounge
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
2.5 star property
Granite City
9.2 out of 10, Wonderful, (488)
"This hotel was well kept,the breakfast was excellent. Stsff was friendly. "
United States
Dennis M
$112 nightly
The price is $124
Jan 4 - Jan 5, 2026
Total with taxes and fees
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Lobby
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
Edwardsville
8.4 out of 10, Very Good, (808)
"Great staff, breakfast was excellent and rooms were clean"
United States
Carlos
$98 nightly
The price is $113
Jan 11 - Jan 12, 2026
Total with taxes and fees
Comfort Inn Edwardsville - St. Louis
Exterior
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1001)
"Clean room and friendly staff "
United States
Summer Dawn
$89 nightly
The price is $103
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hampton Inn St. Charles St. Peters
Lobby
Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
3.0 star property
Eastport
9.6 out of 10, Exceptional, (1002)
"Staff was super friendly and helpful - when i woke up with a sore throat in the middle of thr night, the staff gathered up hit tea and honey for me... cannot ask for a more kind and helpful staff!"
United States
Jamie
$98 nightly
The price is $113
Jan 4 - Jan 5, 2026
Total with taxes and fees
Drury Inn & Suites St. Louis Collinsville
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1251)
"Great stay and staff "
United States
Mykeshia
$106 nightly
The price is $126
Dec 30 - Dec 31
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cross Keys Hotel Reviews

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

10/10 Excellent
"The room was spacious, and breakfast was very good with great coffee."
Susan 1-night trip
Posted 1 day ago
Embassy Suites by Hilton St. Louis Downtown

More cheap stays in Cross Keys

Relax Inn Saint Charles

Relax Inn Saint Charles

3800 Harry S Truman Blvd St. Charles MO
$58 nightly
The price is $67 total per night from Dec 28 to Dec 29
$67 total
Dec 28 - Dec 29
Total with taxes and fees
6.4/10 (1,001 reviews)

Hotels in Cross Keys with star-rating

Frequently asked questions

Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Cross Keys hotel for you.
How can I save on a Cross Keys hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Cross Keys hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Cross Keys hotel?
Prices for hotels in Cross Keys often vary, but you can find a great deal from $66 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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