Find 4 Star Hotels in Upstate South Carolina, SC from $125

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Check availability on Upstate South Carolina 4 Star Hotels

Compare Upstate South Carolina 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
9.6 out of 10, Exceptional, (394)
"Very expensive but great location. "
United States
Mary Ellen
$287 nightly
The price is $316
Nov 16 - Nov 17
Total with taxes and fees
Grand Bohemian Lodge Greenville, Autograph Collection
The Shepherd Hotel Downtown Clemson
4.0 star property
9.8 out of 10, Exceptional, (713)
"Very nice hotel, great staff"
United States
Erin
$189 nightly
The price is $210
Oct 27 - Oct 28
Total with taxes and fees
The Shepherd Hotel Downtown Clemson
The Westin Poinsett Greenville
4.0 star property
9.2 out of 10, Wonderful, (1005)
"Very courteous and helpful staff "
United States
ANDREW
$189 nightly
The price is $208
Nov 23 - Nov 24
Total with taxes and fees
The Westin Poinsett Greenville
Hotel Hartness
4.0 star property
9.8 out of 10, Exceptional, (605)
"Wonderful boutique hotel!!"
United States
Mary Ellen
$199 nightly
The price is $219
Nov 16 - Nov 17
Total with taxes and fees
Hotel Hartness
Greenville Marriott
4.0 star property
8.6 out of 10, Excellent, (600)
"we enjoyed the bar"
United States
Elizabeth
$114 nightly
The price is $125
Nov 23 - Nov 24
Total with taxes and fees
Greenville Marriott
Mint House Greenville - Downtown
4.0 star property
9.2 out of 10, Wonderful, (753)
"Excellent stay as always! "
United States
Elena
Mint House Greenville - Downtown
The Abernathy of Clemson
4.0 star property
9.6 out of 10, Exceptional, (548)
"Great place for visiting the university "
United States
Guy
$164 nightly
The price is $183
Oct 28 - Oct 29
Total with taxes and fees
The Abernathy of Clemson
Park Place Apartments by Landing
4.0 star property
7.8 out of 10, Good, (40)
"This was false advertising. Property name is not the same and their app did not work and we could not get into the property NOR get anyone on the phone. We spent 2 hours on the phone to try and get in and finally had to book another hotel. And it’s been a week and my money has yet to be returned even though Expedia said they would refund me "
United States
Ashley
Park Place Apartments by Landing
Liberty Hall Bed and Breakfast
4.0 star property
10.0 out of 10, Exceptional, (75)
"Beautiful home, very clean, easy self check in. I unfortunately was not able to join breakfast during my stay, but the host gave me a goodie bag to go, which was much appreciated! "
United States
Debra
$210 nightly
The price is $233
Nov 11 - Nov 12
Total with taxes and fees
Liberty Hall Bed and Breakfast
Hotel Domestique
4.0 star property
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
United States
Chuck
$409 nightly
The price is $450
Nov 23 - Nov 24
Total with taxes and fees
Hotel Domestique
The Station by Compo Hotels
4.0 star property
10.0 out of 10, Exceptional, (12)
"Great place"
United States
Edward
$282 nightly
The price is $311
Nov 17 - Nov 18
Total with taxes and fees
The Station by Compo Hotels
228 Lakeland
4.0 star property
228 Lakeland
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Learn more about Upstate South Carolina

Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Greenville - Spartanburg
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Upstate South Carolina Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Upstate South Carolina, South Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Upstate South Carolina 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Upstate South Carolina. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Upstate South Carolina, South Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Upstate South Carolina hotels offer everything your heart desires.

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