Find Casino Hotels & Resorts in Affton, MO from $82

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Our top choices for Affton hotels with a casino

Casino
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
Maryland Heights
8.4 out of 10, Very Good, (2216)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
$117 nightly
The price is $137
Jan 6 - Jan 7, 2026
Total with taxes and fees
Hollywood Casino & Hotel St. Louis
Exterior
Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel
2.5 star property
Woodson Terrace
9.2 out of 10, Wonderful, (1001)
"Room was nice and comfortable, pool was awesome, and breakfast left us all happy"
United States
Letez
$114 nightly
The price is $136
Dec 19 - Dec 20
Total with taxes and fees
Best Western Plus St. Louis Airport Hotel
Free daily buffet breakfast
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1001)
"Love this hotel. "
United States
Lisa
$115 nightly
The price is $132
Jan 1 - Jan 2, 2026
Total with taxes and fees
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1242)
"Great hospitality"
United States
Alejandro
$107 nightly
The price is $127
Dec 18 - Dec 19
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
Exterior
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very Good, (1002)
"Nice staff at reception. "
United States
Denise
$79 nightly
The price is $91
Dec 14 - Dec 15
Total with taxes and fees
Comfort Suites St Charles - St Louis
Premium bedding, desk, iron/ironing board, free cribs/infant beds
Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very Good, (1000)
"I'd stay at this place again. "
United States
Suzanne
$71 nightly
The price is $82
Dec 25 - Dec 26
Total with taxes and fees
Super 8 by Wyndham St Charles
Casino
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1003)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
$166 nightly
The price is $194
Dec 14 - Dec 15
Total with taxes and fees
Ameristar Casino Resort and Spa
Front of property - evening/night
Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG
3.5 star property
Earth City
7.6 out of 10, Good, (1001)
"Staff was welcoming and pleasant "
United States
Michelle
$74 nightly
The price is $85
Jan 1 - Jan 2, 2026
Total with taxes and fees
Holiday Inn St. Louis Arpt West-Earth City by IHG
Lobby
Best Western St. Louis Airport North Hotel & Suites

Best Western St. Louis Airport North Hotel & Suites

Best Western St. Louis Airport North Hotel & Suites
2.5 star property
Hazelwood
7.4 out of 10, Good, (860)
"Friendly front desk"
United States
Phillip
$79 nightly
The price is $96
Dec 18 - Dec 19
Total with taxes and fees
Best Western St. Louis Airport North Hotel & Suites
Casino
Casino Queen Hotel

Casino Queen Hotel

Casino Queen Hotel
3.0 star property
East St. Louis
7.6 out of 10, Good, (1970)
"Clean room, friendly staff, lobby was nice and welcoming. "
United States
Tricia
$99 nightly
The price is $115
Dec 14 - Dec 15
Total with taxes and fees
Casino Queen Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Affton Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
" I felt very comfortable and safe while staying a Pear Tree. The breakfast was great and I looked forward to the popcorn in the evening"
Kathy 6-night trip
Posted 18 hours ago
Pear Tree Inn St. Louis Near Union Station

Frequently asked questions

Searching for casino hotels in Affton?
Looking to hit the casinos in Affton? You're in luck, because you'll find River City Casino, Horseshoe St. Louis Casino, and Casino Queen in the area, as well as much more to see and do. You might want to visit popular sights in the larger area including St. Louis Union Station and Gateway Arch.
When should I take my casino trip to Affton?
You'll likely spend much of your trip indoors, but if you're planning to venture beyond the casino, looking at local weather trends is a good idea. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Affton is 53 inches.
What is there to do in Affton?
You can head to Saint Louis Galleria Mall, Soulard Farmer's Market, or Washington Avenue Historic District to shop for the perfect souvenir. Check out St. Louis Science Center, St. Louis Art Museum, or The Muny Theater for a taste of local culture. If you're looking to add to your itinerary, you can also visit St. Louis Union Station and Gateway Arch.
What are my transportation options for my casino getaway to Affton?
Getting around Affton is easier with these transportation options: You can book a flight to the closest airport, which is St. Louis Lambert Intl. Airport (STL), 13.4 mi (21.5 km) from the city center. If you'd like to venture out around the area, consider renting a car to take in more sights.

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