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Find luxury hotels in Cape Girardeau, MO

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Pick from 4 Cape Girardeau Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Property grounds
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
10.0 out of 10, Exceptional, (202)
"beautiful place. great location. recommend to anyone"
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Lobby
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (780)
"I liked the two rooms. Having breakfast included made traveling much more convenient."
The price is $108
$122 total
includes taxes & fees
May 21 - May 22
Drury Inn & Suites Cape Girardeau
Seasonal outdoor pool
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1001)
"Reasonably price, clean, comfortable bed the only down fall is the rooms were tiny! "
The price is $67
$76 total
includes taxes & fees
May 22 - May 23
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby
Quality Inn
2.5 star property
7.0 out of 10, Good, (459)
"Easy snd comfy"
The price is $67
$76 total
includes taxes & fees
May 19 - May 20
Quality Inn
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Cape Girardeau Luxury Hotels information

 

Luxury Hotels in Cape Girardeau

4

Highest price
$108
Cheapest price
$67
Number of guest reviews
2,386
Total number of hotels in Cape Girardeau
149

 

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Cape Girardeau?
Use Expedia to arrange your flight to Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport or Cairo, IL (CIR-Cairo Regional) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a vacation, so we make it easy to get what you’d like to make your stay relaxing and comfortable. If you want an upscale hotel that has fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Cape Girardeau offers. During your visit, you might want to enjoy the university which Cape Girardeau is known for.
How many luxury hotels will I find in Cape Girardeau?
Lie in the lap of luxury during your getaway to Cape Girardeau in one of Expedia’s 6 luxury hotels.
What's the best time to vacation in Cape Girardeau?
Planning for the weather is an important factor for making your trip to Cape Girardeau a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.
What's there to see and do in Cape Girardeau?
Enjoy all that Cape Girardeau has to offer and visit Isle Casino Cape Girardeau, Riverfront Bridge Park, and Show Me Center. If you have a bit of extra time while you’re in the area, you might want to check out Cape Splash Family Aquatic Center and Hunter Valley Winery.

Recent reviews of Cape Girardeau hotels
Expedia verified reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

5/5 Excellent
"I liked the two rooms. Having breakfast included made traveling much more convenient."
A verified traveler stayed at Drury Inn & Suites Cape Girardeau
Posted 3 days ago
Drury Inn & Suites Cape Girardeau