Find all hotels by Independent in Central San Diego, CA from $64

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Compare rooms and suites by Independent in Central San Diego with rates, reviews, and availability. Most hotels are fully refundable.

Legacy Resort Hotel & Spa

4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2984)
"Great hotel"
United States
Michael
$152 nightly
The price is $175
Dec 7 - Dec 8
Total with taxes and fees
Legacy Resort Hotel & Spa

Lafayette Hotel & Club

4.0 star property
University Heights
9.4 out of 10, Exceptional, (1307)
"Loved everything, I could stay there forever"
United States
Mariana
$226 nightly
The price is $259
Dec 9 - Dec 10
Total with taxes and fees
Lafayette Hotel & Club

The Atwood Hotel San Diego - SeaWorld/Zoo

3.0 star property
Mission Valley
8.0 out of 10, Very Good, (1818)
"Staff was friendly from check in "
United States
Carmelo
$81 nightly
The price is $94
Dec 8 - Dec 9
Total with taxes and fees
The Atwood Hotel San Diego - SeaWorld/Zoo

California Suites Hotel

2.0 star property
Clairemont
7.6 out of 10, Good, (2188)
"It was an excellent stay"
Canada
France
$71 nightly
The price is $82
Dec 3 - Dec 4
Total with taxes and fees
California Suites Hotel

Handlery Hotel

3.5 star property
Mission Valley
8.2 out of 10, Very Good, (2224)
"Staff was amazing and very accommodating. Always recommended staying here. "
United States
Taja
$83 nightly
The price is $96
Jan 1 - Jan 2, 2026
Total with taxes and fees
Handlery Hotel

Pleasant Inn

2.5 star property
Clairemont
8.4 out of 10, Very Good, (1262)
"Great stay!"
United States
Sergio
$89 nightly
The price is $102
Dec 3 - Dec 4
Total with taxes and fees
Pleasant Inn

E-Z 8 Motel Old Town

2.5 star property
Old Town San Diego
6.4 out of 10, (2092)
"The property is a well-maintained motel conveniently located near major freeways, making it easily accessible. It’s competitively priced and offers great value for the area—absolutely perfect for a relaxing and affordable staycation. "
United States
Myiesha
$56 nightly
The price is $64
Dec 2 - Dec 3
Total with taxes and fees
E-Z 8 Motel Old Town

Riverleaf Inn Mission Valley

2.5 star property
Mission Valley
6.4 out of 10, (1033)
"Would definitely stay again!"
United States
Ayva Renee
$64 nightly
The price is $73
Dec 4 - Dec 5
Total with taxes and fees
Riverleaf Inn Mission Valley

Old Town Western Inn & Suites

2.5 star property
Old Town San Diego
7.6 out of 10, Good, (1021)
"This was a cute stay in a cute area for so much to do! "
United States
Stephanie
$85 nightly
The price is $96
Dec 7 - Dec 8
Total with taxes and fees
Old Town Western Inn & Suites

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

2.5 star property
Hillcrest
8.4 out of 10, Very Good, (263)
"Overall good place."
United States
Isaac
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central San Diego Hotel Reviews

Find out more about Central San Diego

Central San Diego, San Diego County Hotel Guide

Would you like to discover a different side of San Diego County? The neighborhood of Central San Diego is one option. It's located 8 miles north of the city center.

San Diego County is well known for the San Diego State University, the San Diego Zoo and the Balboa Park.

If your young ones are bored, Boomers San Diego is a fun-filled spot for those traveling with teenagers. You'll find the Residence Inn By Marriott San Diego Central and Hampton Inn San Diego-Kearny Mesa in the area surrounding this attraction, and they're both top-notch accommodation picks.

Visitors to San Diego County will find a range of accommodation styles in Central San Diego. Establishments at the more affordable end of the scale include the Holiday Inn Express San Diego Airport - Old Town and Hotel Iris - San Diego.

If you would prefer a place to base yourself that is a bit more high-end, you could check out the latest deals at Central San Diego's the Hyatt Regency La Jolla and San Diego Marriott La Jolla.

If you're in need of some caffeine to help you get through all that sightseeing, Refresh Coffee is one of the leading places in Central San Diego to get your fix. The hearty meal options at Adrian's Café will satisfy hungrier travelers who want a sit-down meal. When darkness falls, be prepared to hit the bars! A favorite local haunt is Elbowroom.

Accommodation options near Central San Diego

There's no need to worry if hotel rooms in Central San Diego are unavailable. Why not broaden your search and look up what's available in Kearny Mesa? You'll find the suburb 0.3 miles away. Another option is to make a reservation at a hotel in Clairemont, which is another San Diego County neighborhood.

At Expedia, we want your visit to San Diego County to be as rich and rewarding as it can be. The San Diego County vacation travel guide and San Diego County hotels page are great places to discover more about this exciting destination!

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