Central San Diego Vacations from $590
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Central San Diego vacation packages
Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel
Downtown San Diego
Price was $1,490, price is now $590 per person
$590
per person
Aug 30 - Sep 5
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Diego (SAN)
8.6/10 Excellent! (2,204 reviews)
Great location. Parking is a bit annoying but other than that a great place to stay and I would stay again.
Reviewed on Jun 17, 2026
The Wayfarer San Diego
Mission Beach
Save 100% on your flight
Price was $2,438, price is now $1,371 per person
$1,371
per person
Aug 30 - Sep 5
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Diego (SAN)
9.4/10 Exceptional! (1,795 reviews)
Really great location!!! Rooms were comfortable including the bed. Super clean. Love that you get an ocean view from the pool and our room. Nice and helpful staff!
Reviewed on Jun 17, 2026
Hyatt Vacation Club at The Welk, San Diego Area
Lawrence Welk Resort Village
Save 100% on your flight
Price was $1,023, price is now $601 per person
$601
per person
Aug 30 - Sep 5
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Diego (SAN)
8.4/10 Very Good! (1,874 reviews)
Family-friendly, clean, staff was great and helpful. Would definitely have to stay here again, a lot of things to do!
Reviewed on Jun 19, 2026
Guesthouse Hotel at La Valle
Save 100% on your flight
Price was $1,401, price is now $829 per person
$829
per person
Aug 30 - Sep 5
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Diego (SAN)
9.4/10 Exceptional! (125 reviews)
They have refreshed and updated this hotel since I last visited in late 2024 and overall, changes are good. Staff were very friendly. They are still working out some kinks-restaurant and snack bar couldn’t do room charges, but visitors can pay by credit cards. The family pool is great if you are traveling with children.
I did not use the spa, but they had a good menu of choices.
Reviewed on Jun 11, 2026
Paradise Point Resort & Spa
Mission Bay
Save 100% on your flight
Price was $1,419, price is now $859 per person
$859
per person
Aug 30 - Sep 5
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Diego (SAN)
8.8/10 Excellent! (2,648 reviews)
It's our third time at the resort. We absolutely love everything about it and how it feels like a home away from home!!
Reviewed on Jun 19, 2026
Don't see what you're looking for?
See all available trips from Columbus to Central San Diego
View all tripsWhere to stay in Central San Diego
Find the best Central San Diego areas and neighborhoods for the activities you enjoy most. Learn more about Central San Diego
Mission Valley
3 out of top 10 points of interest in this area
4/5(5,069 area reviews)
Boasting major shopping malls like Fashion Valley Mall and Westfield Mission Valley, this area offers entertainment and historic sites such as Mission San Diego de Alcalá and Presidio Park. Easily accessible via the San Diego Trolley system's Green Line.
Discover the most popular places to visit in Central San Diego
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
Hotel Circle
Hotel Circle is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Check out the shops and top-notch restaurants in this family-friendly area.
Balboa Park
Culture and nature converge in this diverse park located in the heart of the city.
What to do in Central San Diego
Oceanside Whale and Dolphin Watching Adventures
$57
per adult
90% of travellers recommend
San Diego Old Town Trolley Hop-On Hop-Off Tour
$57
per adult
94% of travellers recommend
Central San Diego Hotel Deals
Best Western Seven Seas
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $133 total per night from Jun 28 to Jun 29
$133 total
Jun 28 - Jun 29
Total with taxes and fees
8/10 Very Good! (3,618 reviews)
"Había cabellos en el cajón y el refri no servía para nada ,tengo Video de que le tome por qué no servía,marque a recepción por qué había un olor Feo en el cuarto y nunca mandaron a alguien a revisar solo espero que si me den completo mi depósito"
Reviewed on Jun 17, 2026
California Suites Hotel
5415 Clairemont Mesa Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $125 total per night from Jun 22 to Jun 23
$125 total
Jun 22 - Jun 23
Total with taxes and fees
7.8/10 Good! (2,648 reviews)
"Needs updating!"
Reviewed on Jun 19, 2026
Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $133 total per night from Jul 19 to Jul 20
$133 total
Jul 19 - Jul 20
Total with taxes and fees
8/10 Very Good! (2,824 reviews)
"Great location, pool was heater with a very nice setup including jacuzzi. Close to everything. The only issue if you come late you may have trouble finding parking If hotel is sold out"
Reviewed on Jun 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Central San Diego Vacation Packages
Central San Diego Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | San Diego Intl. Airport (SAN) |
More vacations you might like
Explore a world of travel with Expedia
- San Diego County Hotels
- San Diego Hotels
- Hotels near Kearny Mesa
- Cheap Hotels in Kearny Mesa
- Motel 6 Hotels in Kearny Mesa
- Pet-Friendly Hotels in Kearny Mesa
- 5 Star Hotels in Kearny Mesa
- Marriott Hotels & Resorts in Kearny Mesa
- Extended Stay America Hotels in Kearny Mesa
- 3 Star Hotels in Kearny Mesa
- Hotels with Kitchenettes in Kearny Mesa
- Hotels with Restaurants in Kearny Mesa
- Resorts & Hotels with Spas in Kearny Mesa
- Hotels with Suites in Kearny Mesa
- Hotels with Free Parking in Kearny Mesa
- Extended Stay Hotels in Kearny Mesa
- Hotels with Balconies in Kearny Mesa
- Casino Hotels in Kearny Mesa
- Hotels with Free Breakfast in Kearny Mesa
- Beach Hotels in Kearny Mesa
- Romantic Hotels in Kearny Mesa
- Hotels with Hot Tubs in Kearny Mesa
- Hotel Wedding Venues Hotels in Kearny Mesa
- Destination Hotels in Kearny Mesa
- Hotels with Connecting Rooms in Kearny Mesa
- Hotels with Bars in Kearny Mesa
- 4 Star Hotels in Kearny Mesa
- Luxury Hotels in Kearny Mesa
- Hotels with Free Airport Shuttle in Kearny Mesa
- Business Hotels in Kearny Mesa
- Kimpton Hotels in Kearny Mesa
- Hyatt Hotels in Kearny Mesa
- Best Western Hotels in Kearny Mesa
- Hotels near Boomers San Diego
- Hotels near Marine Corps Air Station Miramar
- Hotels near Montgomery Field
- Flights to San Diego
- Flights from Montgomery Field
- Flights from Calexico (CXL) to San Diego (MYF)
- Flights from Dallas (DFW) to San Diego (MYF)
- Flights from Corvallis (CVO) to San Diego (MYF)
- Flights from Oceanside (OCN) to San Diego (MYF)
- Flights from Watsonville (WVI) to San Diego (MYF)
- Flights from San Jose (SJC) to San Diego (MYF)
- Flights from Detroit (DTW) to San Diego (MYF)
- Flights from Thermal (TRM) to San Diego (MYF)
- Flights from Salt Lake City (SLC) to San Diego (MYF)
- Flights from Chicago (ORD) to San Diego (MYF)
- Flights from Atlanta (ATL) to San Diego (MYF)
- Flights from San Carlos (SQL) to San Diego (MYF)
- Flights from Phoenix (PHX) to San Diego (MYF)
- Flights from San Francisco (SFO) to San Diego (MYF)
- Flights from New York (JFK) to San Diego (MYF)
- Flights from Portland (PDX) to San Diego (MYF)
- Flights from Boise (BOI) to San Diego (MYF)
- Flights from Oakland (OAK) to San Diego (MYF)
- Flights from Columbus (CMH) to San Diego (MYF)
- Flights from Raleigh (RDU) to San Diego (MYF)
- Flights from St. Louis (STL) to San Diego (MYF)
- Flights from Los Angeles (LAX) to San Diego (MYF)
- Flights from Auburn (AUN) to San Diego (MYF)
- Flights from Indianapolis (IND) to San Diego (MYF)
- Flights from Richland (RLD) to San Diego (MYF)
- Flights from Fort Meade (FME) to San Diego (MYF)
- Flights from Cottonwood (CTW) to San Diego (MYF)
- Flights from Denver (DEN) to San Diego (MYF)
- Flights from Cincinnati (CVG) to San Diego (MYF)
- Flights from Sacramento (SMF) to San Diego (MYF)
- Flights from Fort Myers (RSW) to San Diego (MYF)
- Flights from Las Vegas (LAS) to San Diego (MYF)
- Flights from Greenville (GSP) to San Diego (MYF)
- Flights from Mammoth Lakes (MMH) to San Diego (MYF)
- Flights from Salem (SLE) to San Diego (MYF)
- Flights from Xi'an (XIY) to San Diego (MYF)
- Flights from Bermuda Dunes (UDD) to San Diego (MYF)
- Flights from Santa Barbara (SBA) to San Diego (MYF)
- Flights from Hartford (BDL) to San Diego (MYF)
- Hopscotch Air Harrison (HRO) to San Diego (MYF) flights
- Flights from Ogden (OGD) to San Diego (MYF)
- Flights from Rifle (RIL) to San Diego (MYF)
- Flights from Eureka (EKA) to San Diego (MYF)
- Flights from Renton (RNT) to San Diego (MYF)
- Flights from Scottsdale (SCF) to San Diego (MYF)
- Flights from Washington (WAS) to San Diego (MYF)
- Flights from Hawthorne (HHR) to San Diego (MYF)
- Flights from Kansas City (MCI) to San Diego (MYF)
- Flights from Tulsa (TUL) to San Diego (MYF)
- Car rentals near San Diego
- Car rental San Diego Airport (SAN)
- Car rentals near Kearny Mesa
- Enterprise Rental Cars in Kearny Mesa
- Budget Rental Cars in Kearny Mesa
- Hertz Rental Cars in Kearny Mesa
- Sr Rent A Car Rental Cars in Kearny Mesa
- Avis Rental Cars in Kearny Mesa
- Car rentals near Marine Corps Air Station Miramar
- Car rental San Diego Airport (MYF)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
