Central San Diego Vacations from $421
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Central San Diego vacation packages
Price found within the past 48 hours. Click for updated prices.
Hyatt Vacation Club at The Welk, San Diego Area
Lawrence Welk Resort Village
Save 100% on your flight
Price was $698, price is now $421 per person
$421
per person
Apr 16 - Apr 21
found 24 hours ago
Roundtrip flight included
Chicago (CHI) to San Diego (SAN)
8.2/10 Very Good! (1,508 reviews)
Nice room with free amenities. Feels like home
Reviewed on Feb 2, 2026
Hilton San Diego Gaslamp Quarter
Downtown San Diego
Save 100% on your flight
Price was $1,567, price is now $927 per person
$927
per person
Apr 14 - Apr 19
found 1 day ago
Roundtrip flight included
Chicago (CHI) to San Diego (SAN)
9/10 Wonderful! (232 reviews)
The room was clean and quiet.
Reviewed on Jan 7, 2026
Don't see what you're looking for?
See all available trips from Columbus to Central San Diego
View all tripsWhere to stay in Central San Diego
Find the best Central San Diego areas and neighborhoods for the activities you enjoy most. Learn more about Central San Diego
Mission Valley
3 out of top 10 points of interest in this area
4/5(4,999 area reviews)
Boasting major shopping malls like Fashion Valley Mall and Westfield Mission Valley, this area offers entertainment and historic sites such as Mission San Diego de Alcalá and Presidio Park. Easily accessible via the San Diego Trolley system's Green Line.
Discover the most popular places to visit in Central San Diego
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
Balboa Park
Culture and nature converge in this diverse park located in the heart of the city.
Hotel Circle
Hotel Circle is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Check out the shops and top-notch restaurants in this family-friendly area.
What to do in Central San Diego
San Diego: Museum of Illusions Entry Ticket
$35
per adult
80% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
$71
per adult
88% of travellers recommend
San Diego Old Town Trolley Hop-On Hop-Off Tour
$55
per adult
94% of travellers recommend
Central San Diego Hotel Deals
Best Western Seven Seas
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Feb 8 to Feb 9
$87 total
Feb 8 - Feb 9
Total with taxes and fees
7.8/10 Good! (3,182 reviews)
The Best Western than seven seas is special to me because I stayed there as a child with my parents and grandparents. It is old motor in style San Diego or best Western in its old form.. The staff is great and it has a nice pool and Jacuzzi.. It is very affordable..
Reviewed on Feb 2, 2026
San Diego Marriott La Jolla
4240 La Jolla Village Dr La Jolla CA
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $188 total per night from Feb 6 to Feb 7
$188 total
Feb 6 - Feb 7
Total with taxes and fees
8.4/10 Very Good! (2,249 reviews)
Hotel lobby, guest room very clean. Nice amenities and staff at check in and at bar. Fantastic view from room 405 Convenient location
Reviewed on Feb 3, 2026
Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Feb 8 to Feb 9
$92 total
Feb 8 - Feb 9
Total with taxes and fees
7.8/10 Good! (2,450 reviews)
Great
Reviewed on Jan 29, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Central San Diego Vacation Packages
Central San Diego Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | San Diego Intl. Airport (SAN) |
More vacations you might like
Explore a world of travel with Expedia
- San Diego County Hotels
- San Diego Hotels
- Hotels near Kearny Mesa
- Cheap Hotels in Kearny Mesa
- Motel 6 Hotels in Kearny Mesa
- Pet-friendly Hotels in Kearny Mesa
- 5 Star Hotels in Kearny Mesa
- Marriott Hotels & Resorts in Kearny Mesa
- Extended Stay America Hotels in Kearny Mesa
- 3 Star Hotels in Kearny Mesa
- Hotels with Kitchenettes in Kearny Mesa
- Hotels with Restaurants in Kearny Mesa
- Resorts & Hotels with Spas in Kearny Mesa
- Hotels with Suites in Kearny Mesa
- Hotels with Free Parking in Kearny Mesa
- Extended Stay Hotels in Kearny Mesa
- Hotels with Balconies in Kearny Mesa
- Casino Hotels in Kearny Mesa
- Hotels with Free Breakfast in Kearny Mesa
- Beach Hotels in Kearny Mesa
- Romantic Hotels in Kearny Mesa
- Hotels with Hot Tubs in Kearny Mesa
- Hotel Wedding Venues Hotels in Kearny Mesa
- Destination Hotels in Kearny Mesa
- Hotels with Connecting Rooms in Kearny Mesa
- Hotels with Bars in Kearny Mesa
- 4 Star Hotels in Kearny Mesa
- Luxury Hotels in Kearny Mesa
- Hotels with Free Airport Shuttle in Kearny Mesa
- Business Hotels in Kearny Mesa
- Kimpton Hotels in Kearny Mesa
- Hyatt Hotels in Kearny Mesa
- Best Western Hotels in Kearny Mesa
- Hotels near Boomers San Diego
- Hotels near Marine Corps Air Station Miramar
- Hotels near Montgomery Field
- Flights to San Diego
- Flights from Montgomery Field
- Flights from Calexico (CXL) to San Diego (MYF)
- Flights from Dallas (DFW) to San Diego (MYF)
- Flights from Corvallis (CVO) to San Diego (MYF)
- Flights from Oceanside (OCN) to San Diego (MYF)
- Flights from Watsonville (WVI) to San Diego (MYF)
- Flights from San Jose (SJC) to San Diego (MYF)
- Flights from Detroit (DTW) to San Diego (MYF)
- Flights from Thermal (TRM) to San Diego (MYF)
- Flights from Salt Lake City (SLC) to San Diego (MYF)
- Flights from Chicago (ORD) to San Diego (MYF)
- Flights from Atlanta (ATL) to San Diego (MYF)
- Flights from San Carlos (SQL) to San Diego (MYF)
- Flights from Phoenix (PHX) to San Diego (MYF)
- Flights from San Francisco (SFO) to San Diego (MYF)
- Flights from New York (JFK) to San Diego (MYF)
- Flights from Portland (PDX) to San Diego (MYF)
- Flights from Boise (BOI) to San Diego (MYF)
- Flights from Oakland (OAK) to San Diego (MYF)
- Flights from Columbus (CMH) to San Diego (MYF)
- Flights from Raleigh (RDU) to San Diego (MYF)
- Flights from St. Louis (STL) to San Diego (MYF)
- Flights from Los Angeles (LAX) to San Diego (MYF)
- Flights from Auburn (AUN) to San Diego (MYF)
- Flights from Indianapolis (IND) to San Diego (MYF)
- Flights from Richland (RLD) to San Diego (MYF)
- Flights from Fort Meade (FME) to San Diego (MYF)
- Flights from Cottonwood (CTW) to San Diego (MYF)
- Flights from Denver (DEN) to San Diego (MYF)
- Flights from Cincinnati (CVG) to San Diego (MYF)
- Flights from Sacramento (SMF) to San Diego (MYF)
- Flights from Fort Myers (RSW) to San Diego (MYF)
- Flights from Las Vegas (LAS) to San Diego (MYF)
- Flights from Greenville (GSP) to San Diego (MYF)
- Flights from Mammoth Lakes (MMH) to San Diego (MYF)
- Flights from Salem (SLE) to San Diego (MYF)
- Flights from Xi'an (XIY) to San Diego (MYF)
- Flights from Bermuda Dunes (UDD) to San Diego (MYF)
- Flights from Santa Barbara (SBA) to San Diego (MYF)
- Flights from Hartford (BDL) to San Diego (MYF)
- Hopscotch Air Harrison (HRO) to San Diego (MYF) flights
- Flights from Ogden (OGD) to San Diego (MYF)
- Flights from Rifle (RIL) to San Diego (MYF)
- Flights from Eureka (EKA) to San Diego (MYF)
- Flights from Renton (RNT) to San Diego (MYF)
- Flights from Scottsdale (SCF) to San Diego (MYF)
- Flights from Washington (WAS) to San Diego (MYF)
- Flights from Hawthorne (HHR) to San Diego (MYF)
- Flights from Kansas City (MCI) to San Diego (MYF)
- Flights from Tulsa (TUL) to San Diego (MYF)
- Car rentals near San Diego
- Car rental San Diego Airport (SAN)
- Car rentals near Kearny Mesa
- Enterprise Rental Cars in Kearny Mesa
- Budget Rental Cars in Kearny Mesa
- Hertz Rental Cars in Kearny Mesa
- SR Rent A Car Rental Cars in Kearny Mesa
- Avis Rental Cars in Kearny Mesa
- Car rentals near Marine Corps Air Station Miramar
- Car rental San Diego Airport (MYF)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
