Central San Diego Vacations from $414
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Central San Diego vacation packages
Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel
Downtown San Diego
Price was $1,081, price is now $414 per person
$414
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (2,204 reviews)
Mi hijo Jorge esposa e hijo se hospedaron, me informaron que todo estuvo muy bien en hotel Sofia,
Reviewed on Jun 14, 2026
Los Bungalows
Save 100% on your flight
Price was $1,573, price is now $891 per person
$891
per person
Aug 1 - Aug 8
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.2/10 Very Good! (536 reviews)
Honestly one of the best hotels I’ve stayed in the views the vibes overall very very peaceful place loved it
Reviewed on Jun 7, 2026
Margaritaville Hotel San Diego Gaslamp Quarter
Downtown San Diego
Save 100% on your flight
Price was $749, price is now $453 per person
$453
per person
Sep 5 - Sep 8
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9/10 Wonderful! (1,384 reviews)
Stayed there for a conference, great choice
Reviewed on Jun 15, 2026
Ocean Park Inn
Pacific Beach
Save 100% on your flight
Price was $2,172, price is now $1,335 per person
$1,335
per person
Jul 27 - Aug 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.4/10 Exceptional! (1,005 reviews)
Excellent location. Great view from our balcony. Nice pool. Free breakfast.
We thoroughly enjoyed our stay.
Reviewed on Jun 15, 2026
Don't see what you're looking for?
See all available trips from Columbus to Central San Diego
View all tripsWhere to stay in Central San Diego
Find the best Central San Diego areas and neighborhoods for the activities you enjoy most. Learn more about Central San Diego
Mission Valley
3 out of top 10 points of interest in this area
4/5(5,069 area reviews)
Boasting major shopping malls like Fashion Valley Mall and Westfield Mission Valley, this area offers entertainment and historic sites such as Mission San Diego de Alcalá and Presidio Park. Easily accessible via the San Diego Trolley system's Green Line.
Central San Diego Hotel Deals
Best Western Seven Seas
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Jun 17 to Jun 18
$97 total
Jun 17 - Jun 18
Total with taxes and fees
8/10 Very Good! (3,641 reviews)
"Centrally located (Hotel Circle) to San Diego sightseeing."
Reviewed on Jun 15, 2026
Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S San Diego CA
$114 nightly
The price is $131 total per night from Jun 17 to Jun 18
$131 total
Jun 17 - Jun 18
Total with taxes and fees
8/10 Very Good! (2,823 reviews)
"Great room & breakfast highly recommend"
Reviewed on Jun 15, 2026
California Suites Hotel
5415 Clairemont Mesa Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $114 total per night from Jun 16 to Jun 17
$114 total
Jun 16 - Jun 17
Total with taxes and fees
7.8/10 Good! (2,654 reviews)
"Really great hotel for the price. We will definitely be staying here again with our little ones"
Reviewed on Jun 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Central San Diego Vacation Packages
Central San Diego Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | San Diego Intl. Airport (SAN) |
More vacations you might like
Explore a world of travel with Expedia
- San Diego County Hotels
- San Diego Hotels
- Hotels near Kearny Mesa
- Cheap Hotels in Kearny Mesa
- Motel 6 Hotels in Kearny Mesa
- Pet-Friendly Hotels in Kearny Mesa
- 5 Star Hotels in Kearny Mesa
- Marriott Hotels & Resorts in Kearny Mesa
- Extended Stay America Hotels in Kearny Mesa
- 3 Star Hotels in Kearny Mesa
- Hotels with Kitchenettes in Kearny Mesa
- Hotels with Restaurants in Kearny Mesa
- Resorts & Hotels with Spas in Kearny Mesa
- Hotels with Suites in Kearny Mesa
- Hotels with Free Parking in Kearny Mesa
- Extended Stay Hotels in Kearny Mesa
- Hotels with Balconies in Kearny Mesa
- Casino Hotels in Kearny Mesa
- Hotels with Free Breakfast in Kearny Mesa
- Beach Hotels in Kearny Mesa
- Romantic Hotels in Kearny Mesa
- Hotels with Hot Tubs in Kearny Mesa
- Hotel Wedding Venues Hotels in Kearny Mesa
- Destination Hotels in Kearny Mesa
- Hotels with Connecting Rooms in Kearny Mesa
- Hotels with Bars in Kearny Mesa
- 4 Star Hotels in Kearny Mesa
- Luxury Hotels in Kearny Mesa
- Hotels with Free Airport Shuttle in Kearny Mesa
- Business Hotels in Kearny Mesa
- Kimpton Hotels in Kearny Mesa
- Hyatt Hotels in Kearny Mesa
- Best Western Hotels in Kearny Mesa
- Hotels near Boomers San Diego
- Hotels near Marine Corps Air Station Miramar
- Hotels near Montgomery Field
- Flights to San Diego
- Flights from Montgomery Field
- Flights from Calexico (CXL) to San Diego (MYF)
- Flights from Dallas (DFW) to San Diego (MYF)
- Flights from Corvallis (CVO) to San Diego (MYF)
- Flights from Oceanside (OCN) to San Diego (MYF)
- Flights from Watsonville (WVI) to San Diego (MYF)
- Flights from San Jose (SJC) to San Diego (MYF)
- Flights from Detroit (DTW) to San Diego (MYF)
- Flights from Thermal (TRM) to San Diego (MYF)
- Flights from Salt Lake City (SLC) to San Diego (MYF)
- Flights from Chicago (ORD) to San Diego (MYF)
- Flights from Atlanta (ATL) to San Diego (MYF)
- Flights from San Carlos (SQL) to San Diego (MYF)
- Flights from Phoenix (PHX) to San Diego (MYF)
- Flights from San Francisco (SFO) to San Diego (MYF)
- Flights from New York (JFK) to San Diego (MYF)
- Flights from Portland (PDX) to San Diego (MYF)
- Flights from Boise (BOI) to San Diego (MYF)
- Flights from Oakland (OAK) to San Diego (MYF)
- Flights from Columbus (CMH) to San Diego (MYF)
- Flights from Raleigh (RDU) to San Diego (MYF)
- Flights from St. Louis (STL) to San Diego (MYF)
- Flights from Los Angeles (LAX) to San Diego (MYF)
- Flights from Auburn (AUN) to San Diego (MYF)
- Flights from Indianapolis (IND) to San Diego (MYF)
- Flights from Richland (RLD) to San Diego (MYF)
- Flights from Fort Meade (FME) to San Diego (MYF)
- Flights from Cottonwood (CTW) to San Diego (MYF)
- Flights from Denver (DEN) to San Diego (MYF)
- Flights from Cincinnati (CVG) to San Diego (MYF)
- Flights from Sacramento (SMF) to San Diego (MYF)
- Flights from Fort Myers (RSW) to San Diego (MYF)
- Flights from Las Vegas (LAS) to San Diego (MYF)
- Flights from Greenville (GSP) to San Diego (MYF)
- Flights from Mammoth Lakes (MMH) to San Diego (MYF)
- Flights from Salem (SLE) to San Diego (MYF)
- Flights from Xi'an (XIY) to San Diego (MYF)
- Flights from Bermuda Dunes (UDD) to San Diego (MYF)
- Flights from Santa Barbara (SBA) to San Diego (MYF)
- Flights from Hartford (BDL) to San Diego (MYF)
- Hopscotch Air Harrison (HRO) to San Diego (MYF) flights
- Flights from Ogden (OGD) to San Diego (MYF)
- Flights from Rifle (RIL) to San Diego (MYF)
- Flights from Eureka (EKA) to San Diego (MYF)
- Flights from Renton (RNT) to San Diego (MYF)
- Flights from Scottsdale (SCF) to San Diego (MYF)
- Flights from Washington (WAS) to San Diego (MYF)
- Flights from Hawthorne (HHR) to San Diego (MYF)
- Flights from Kansas City (MCI) to San Diego (MYF)
- Flights from Tulsa (TUL) to San Diego (MYF)
- Car rentals near San Diego
- Car rental San Diego Airport (SAN)
- Car rentals near Kearny Mesa
- Enterprise Rental Cars in Kearny Mesa
- Budget Rental Cars in Kearny Mesa
- Hertz Rental Cars in Kearny Mesa
- Sr Rent A Car Rental Cars in Kearny Mesa
- Avis Rental Cars in Kearny Mesa
- Car rentals near Marine Corps Air Station Miramar
- Car rental San Diego Airport (MYF)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
