Central San Diego Vacation Rentals

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Our top choices for Central San Diego vacation rentals

Lobby sitting area

Aparthotel in Hillcrest

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
8.4 out of 10, Very Good, (273 reviews)
"Overall good place."
United States
Isaac
$100 nightly
The price is $113
Jan 19 - Jan 20
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

Aparthotel in Middletown

City24 Hotel Little Italy Mission Hills
4.5 star property
9.6 out of 10, Exceptional, (108 reviews)
"would definitely go back and stay there again "
United States
Kounwick
$178 nightly
The price is $201
Jan 26 - Jan 27
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
In-room safe, iron/ironing board, free WiFi, bed sheets

Cottage in Mid-City

Cozy 2-Bedroom Cottage Near Balboa Park
2.0 star property
$211 nightly
The price is $235
Jan 18 - Jan 19
Total with taxes and fees
Cozy 2-Bedroom Cottage Near Balboa Park
Property grounds

Cottage in Old Town San Diego

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
10.0 out of 10, Exceptional, (269 reviews)
"We enjoyed our stay. The place was perfect and there was even a dog bed, toys, and a water dish filled with water waiting for us when we got there. Within walking distance to lots of dog friendly restaurants and within a 10-15min drive to all the things we wanted to do in San Diego, including an off leash dog beach. Would stay here again."
United States
Michele S.
$211 nightly
The price is $235
Jan 18 - Jan 19
Total with taxes and fees
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Beach nearby

Apartment in Mission Valley

Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
9.2 out of 10, Wonderful, (56 reviews)
"Had a great time in San Diego. Will definitely stay there again!"
United States
Xavier Hicks H.
$295 nightly
The price is $328
Jan 18 - Jan 19
Total with taxes and fees
Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
Outdoor dining

Apartment in Golden Hill

Sunny Golden Hill Studio
8.8 out of 10, Excellent, (15 reviews)
"Daniel’s space was the perfect spot forour short weekend getaway. The space was very welcoming and adorned with great art work. Daniel also made sure to check in with us to guarantee that our stay went well. We are saving this spot for our future stays in San Diego and sharing it with our loved ones for theirs. "
United States
Melanny R.
$172 nightly
The price is $192
Jan 18 - Jan 19
Total with taxes and fees
Sunny Golden Hill Studio
Desk, iron/ironing board, WiFi, bed sheets

Apartment in Bankers Hill

Cozy Studio Near Balboa Park
2.0 star property
$239 nightly
The price is $239
Jan 18 - Jan 19
Total with taxes and fees
Cozy Studio Near Balboa Park
Living area

Vacation Home in North Park

3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC
2.0 star property
5.0 out of 10, (2 reviews)
"Loved how there was a bedroom on each floor along with its own bathroom "
United States
Richelle P.
$299 nightly
The price is $332
Jan 18 - Jan 19
Total with taxes and fees
3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC
Terrace/patio

Apartment in Golden Hill

1 mile to Gaslamp—eScooters, Hot tub, Sauna
2.0 star property
10.0 out of 10, Exceptional, (13 reviews)
"Tiny but clean as a whistle and easy access to Balboa Park and Coronado Island."
United States
Dee Dee S.
$1,257 nightly
The price is $1,276
Jan 22 - Jan 23
Total with taxes and fees
1 mile to Gaslamp—eScooters, Hot tub, Sauna
Fridge, microwave, oven, stovetop

Vacation Home in Mid-City

Beautiful Normal Heights Living
2.0 star property
10.0 out of 10, Exceptional, (74 reviews)
"Great dog-friendly location with lots of great local dining options. Welcoming hosts, nice coffee, very comfortable home!"
United States
Erika Van Bramer Mallory R.
$286 nightly
The price is $318
Jan 19 - Jan 20
Total with taxes and fees
Beautiful Normal Heights Living
Desk, iron/ironing board, travel crib, free WiFi

Vacation Home in University Heights

Chic 3BR Spanish Bungalow in Walkable North Park
2.0 star property
9.8 out of 10, Exceptional, (6 reviews)
"Great communication from owner. Nice house and a convenient spot to stay. "
United States
Jeff S.
Chic 3BR Spanish Bungalow in Walkable North Park
Beach towels

Vacation Home in Bay Ho

Adorable 1 bedroom house 8 min from La Jolla!
10.0 out of 10, Exceptional, (45 reviews)
"The property is centrally located to everything we were doing. Perfect for a couple. "
United States
Timothy N.
$220 nightly
The price is $245
Jan 19 - Jan 20
Total with taxes and fees
Adorable 1 bedroom house 8 min from La Jolla!
Terrace/patio

Vacation Home in Mid-City

Fun-filled Casita w/Incredible Outdoor Living
2.0 star property
10.0 out of 10, Exceptional, (1 review)
"Our family really appreciated our stay! The whole premise was very clean, all amenities were well stocked, and the host was very responsive. Our family had lots of fun cooking together on the grill and playing pool and ping pong! The place was very spacious and clean, the only uncomfortable part was not having a large dining table. The neighborhood also seemed pretty safe. The house was conveniently located, with SD downtown and a lot of places we wanted to go to within 10-20 minutes of driving...
United States
Esther K.
$437 nightly
The price is $486
Jan 19 - Jan 20
Total with taxes and fees
Fun-filled Casita w/Incredible Outdoor Living
Property grounds

Vacation Home in Mid-City

Private Cozy Clean, close to EVERYTHING
10.0 out of 10, Exceptional, (49 reviews)
"We had the best stay! The home was perfect for what we needed and very clean! It is located so close to everything you could want to do! David was very responsive and we couldn’t have asked for better! We can’t wait to visit again!"
United States
Courtney B.
$334 nightly
The price is $371
Jan 26 - Jan 27
Total with taxes and fees
Private Cozy Clean, close to EVERYTHING
Interior

Vacation Home in Linda Vista

Art Gallery Family Home - Southern California Style - Excellent Location
9.8 out of 10, Exceptional, (25 reviews)
"Nice house. Good location."
United States
Andrew K.
$465 nightly
The price is $517
Jan 20 - Jan 21
Total with taxes and fees
Art Gallery Family Home - Southern California Style - Excellent Location
Outdoor dining

Vacation Home in Mira Mesa

Super Spacious Family Vacation Home!
9.6 out of 10, Exceptional, (27 reviews)
"Second time staying here. Very spacious, very clean, has all the amenities you need, close to many restaurants, shopping and activities. "
United States
David H.
$809 nightly
The price is $901
Feb 3 - Feb 4
Total with taxes and fees
Super Spacious Family Vacation Home!
1 bedroom, hypo-allergenic bedding, memory foam beds, desk

Vacation Home in Mid-City

Stylish 1Br Retreat w/Garage AC Close 2 Everything
9.6 out of 10, Exceptional, (5 reviews)
"The stay was wonderful! Our first time staying at this property and we would definitely stay again! It was a lovely cute spot and was located perfectly near the Mission Beach and Sea World!The owner was always responsive and extremely helpful during the check in process as well! Thank you so much for such a wonderful experience!"
United States
Jerome F.
Stylish 1Br Retreat w/Garage AC Close 2 Everything
Microwave, coffee/tea maker, toaster, cookware/dishes/utensils

Vacation Home in Hillcrest

NEW STUDIO HIDDEN GEM ~ BEST LOCATION HILLCREST ~ CLOSE TO ALL ATTRACTIONS OF SD
9.4 out of 10, Exceptional, (53 reviews)
"Was an absolutely fantastic stay, really close to the convention center for comic con. And the price was unbeatable! Very homey feel that made us feel relaxed after a long day out. Will absolutely be back next year!"
United States
Nick M.
$185 nightly
The price is $206
Jan 19 - Jan 20
Total with taxes and fees
NEW STUDIO HIDDEN GEM ~ BEST LOCATION HILLCREST ~ CLOSE TO ALL ATTRACTIONS OF SD
Property grounds

Apartment in North Park

Viva California! Right in the Heart of all the Fun! Firepit, BBQ, walk to eats
9.2 out of 10, Wonderful, (5 reviews)
"Great location. Check in and out were super easy."
United States
narges d.
Viva California! Right in the Heart of all the Fun! Firepit, BBQ, walk to eats
Desk, iron/ironing board, free WiFi, bed sheets

Apartment in University Heights

Bright North Park Studio with Parking, AC & Yard
10.0 out of 10, Exceptional, (1 review)
"Everything was just as shown. Very clean, cozy, and a great location. Owner was very accommodating and helpful."
United States
Ben K.
Bright North Park Studio with Parking, AC & Yard
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central San Diego Hotel Reviews

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

10/10 Excellent
"Room was excellent. Very comfortable. I love the friendliness of the staff and the location does not get any better than this. the Trolley is right across the street, (a 5 minute walk). You can get to literally "any place" you need to go in San Diego from the trolley. I will definitely stay here next time i'm in San Diego. "
William 1-night trip
Posted 2 days ago
DoubleTree by Hilton Hotel San Diego - Mission Valley

Find out more about Central San Diego

Everything you need to know about Central San Diego vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Central San Diego vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Central San Diego vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Central San Diego vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Central San Diego. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Central San Diego in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $113 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Central San Diego rentals

At Expedia, we put the best Central San Diego vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Central San Diego rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Central San Diego vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Central San Diego. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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