Central San Diego Vacation Rentals

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Check prices for these dates

In two weeks
Jun 5 - Jun 7
In two months
Jul 17 - Jul 19
In three months
Aug 14 - Aug 16
In four months
Sep 11 - Sep 13

Our top choices for Central San Diego vacation rentals

Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.8 out of 10, Exceptional, (151 reviews)
"Beautiful fully appointed rooms and excellent location."
United States
Michelle
$150 nightly
The price is $169
May 25 - May 26
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
Beach nearby, beach towels

Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (51 reviews)
"Sparkling clean, friendly host and thoughtful layout"
United States
Griff V.
$232 nightly
The price is $258
May 19 - May 20
Total with taxes and fees
Adorable 1 bedroom house 8 min from La Jolla!
Lobby sitting area

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very Good, (364 reviews)
$104 nightly
The price is $117
May 19 - May 20
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
TV

Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches

Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Mid-City
8.0 out of 10, Very Good, (2 reviews)
"Wir hatten eine tolle Zeit in San Diego und in der Wohnung. Die Kommunikation mit Rebecca hat super geklappt. Sie hat uns die nötigen Infos für den Check In zur rightigen Zeit gegeben und war während des Aufenthaltes sehr hilfsbereit. Die Wohnung ist für 4 Personen ausreichend groß und perfekt ausgestattet, inkl Waschmaschine und Trockner. Vor allem die Küche haben wir ausgiebig genutzt und haben sehr viel selbst gekocht. Es fehlten lediglich eine Schere und ein Gemüsemesser. Rebecca hat uns...
Germany
Hanna S.
$449 nightly
The price is $449
May 26 - May 27
Total with taxes and fees
Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Pool

Stylish 1Br Retreat w/Garage AC Close 2 Everything

Stylish 1Br Retreat w/Garage AC Close 2 Everything
Mid-City
9.8 out of 10, Exceptional, (7 reviews)
"It’s within 15 minutes of Riverwalk Golf club and plenty of restaurants. I was very pleased with my stay "
United States
Tyler
$210 nightly
The price is $232
Jun 2 - Jun 3
Total with taxes and fees
Stylish 1Br Retreat w/Garage AC Close 2 Everything
Private kitchen

Cozy Private Home, 10-min From DT, Beach & Parks

Cozy Private Home, 10-min From DT, Beach & Parks
Mid-City
8.2 out of 10, Very Good, (15 reviews)
"Our family stayed for spring break. We found that the location was perfect to be able to get anywhere we needed to go quite conveniently. The house was perfect for what we needed and we were always able to find a parking spot. "
United States
Leah S.
$233 nightly
The price is $259
May 19 - May 20
Total with taxes and fees
Cozy Private Home, 10-min From DT, Beach & Parks
Property grounds

2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay

2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (213 reviews)
" The host greeted us when we got there. She is lovely. There are so many shops and restaurants walking distance and the place is nice and clean. We had a great stay, I would definitely stay again!"
United States
Deana
$196 nightly
The price is $218
May 20 - May 21
Total with taxes and fees
2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay
Terrace/patio

Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
8.4 out of 10, Very Good, (8 reviews)
"Host was very attentive and answering questions quickly. The apartment was clean and had everything needed for a multi day stay. It’s a very relaxing place and enough space to stretch out or to have some privacy. I would say here again if I have a need for a multi day trip back to San Diego.. Thank you for a great experience."
United States
Thomas M.
$270 nightly
The price is $300
May 26 - May 27
Total with taxes and fees
Cozy 2-Bedroom Cottage Near Balboa Park
Exterior

Beautiful Normal Heights Living

Beautiful Normal Heights Living
Mid-City
10.0 out of 10, Exceptional, (90 reviews)
"Great location, nice cozy place, had everything we needed. Would definitely stay again."
United States
Sheila S.
$285 nightly
The price is $317
May 19 - May 20
Total with taxes and fees
Beautiful Normal Heights Living
Property grounds

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (281 reviews)
"We enjoyed our time in the back cottage. Everything we needed was available. We were able to just walk to so many sites and restaurants. Will definitely try to come back again! "
United States
Phillip
$209 nightly
The price is $232
May 26 - May 27
Total with taxes and fees
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Fridge, microwave, oven, stovetop

The Perfect Blend of Comfort & Style in South Park

The Perfect Blend of Comfort & Style in South Park
South Park
10.0 out of 10, Exceptional, (8 reviews)
"Cute vrbo close to amenities. "
Canada
Darrell H.
$268 nightly
The price is $295
May 27 - May 28
Total with taxes and fees
The Perfect Blend of Comfort & Style in South Park
Interior

Perfect Studio in the Best Location of North Park!

Perfect Studio in the Best Location of North Park!
North Park
10.0 out of 10, Exceptional, (4 reviews)
"Peaceful and in a great location"
United States
Laura R.
$252 nightly
The price is $277
May 26 - May 27
Total with taxes and fees
Perfect Studio in the Best Location of North Park!
TV

Upstairs Hillcrest Studio close to Balboa Park

Upstairs Hillcrest Studio close to Balboa Park
University Heights
$283 nightly
The price is $315
May 19 - May 20
Total with taxes and fees
Upstairs Hillcrest Studio close to Balboa Park
Smart TV, fireplace, video games

Luxury 3-Bedroom House in Marvelous San Diego

Luxury 3-Bedroom House in Marvelous San Diego
Mid-City
9.6 out of 10, Exceptional, (16 reviews)
"Lovely cozy place! "
United States
Madison N.
$383 nightly
The price is $426
Jun 3 - Jun 4
Total with taxes and fees
Luxury 3-Bedroom House in Marvelous San Diego
Smart TV, books

5BR/3Bth, King Bed, Yard & Garage, Near Attractions

5BR/3Bth, King Bed, Yard & Garage, Near Attractions
Mira Mesa
$400 nightly
The price is $444
May 19 - May 20
Total with taxes and fees
5BR/3Bth, King Bed, Yard & Garage, Near Attractions
Terrace/patio

1 mile to Gaslamp—eScooters, Hot tub, Sauna

1 mile to Gaslamp—eScooters, Hot tub, Sauna
Golden Hill
10.0 out of 10, Exceptional, (13 reviews)
"We enjoyed the hot tub and quiet environment has a cool vibe"
United States
Sandra a.
$1,266 nightly
The price is $1,286
May 19 - May 20
Total with taxes and fees
1 mile to Gaslamp—eScooters, Hot tub, Sauna
TV

Relaxing Retreat in North Park – 3943

Relaxing Retreat in North Park – 3943
North Park
10.0 out of 10, Exceptional, (1 review)
"The stay and experience there and with the owner was absolutely great. The place was cozy and clean. He was on the spot with all needs that we're needing to be met. "
United States
Jamall D.
$256 nightly
The price is $267
May 27 - May 28
Total with taxes and fees
Relaxing Retreat in North Park – 3943
Terrace/patio

Charming Mid-Century Craftsman ~ Hot Tub/Serene Yd

Charming Mid-Century Craftsman ~ Hot Tub/Serene Yd
North Park
10.0 out of 10, Exceptional, (109 reviews)
"Tasha quickly responded to any questions we had prior to our stay. It felt like a home away from home and the location was walkable to many of our favorite north park spots."
United States
Tiffany J.
$421 nightly
The price is $468
May 20 - May 21
Total with taxes and fees
Charming Mid-Century Craftsman ~ Hot Tub/Serene Yd
1 bedroom, iron/ironing board, WiFi, bed sheets

Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining

Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining
University City
$339 nightly
The price is $378
May 26 - May 27
Total with taxes and fees
Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining
Fridge, microwave, oven, stovetop

North Park 2BR: Yard, BBQ, Garage Parking

North Park 2BR: Yard, BBQ, Garage Parking
North Park
$358 nightly
The price is $391
May 19 - May 20
Total with taxes and fees
North Park 2BR: Yard, BBQ, Garage Parking
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central San Diego Hotel Reviews

Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

2/10 Terrible
"Hi there, we stayed in rooms 1109 and 1111 and there is the Sheraton Club Lounge on the floor right above above (12th) our rooms unbeknownst to us. I understand it has hardwood floors. And every morning around 5 a.m. or 6 a.m. we were woken up by the rolling breakfast carts on the hardwood floors. It sounded like furniture moving every morning! Every day, we assumed it was a one-off issue as we didn't realize it was a club lounge used daily but it happened every morning. By the time we figured out what it was, we were already scheduled to check out. Had we known it was an active lounge with hardwood floors and rolling breakfast carts, we would have requested a room change, but we were also told that we got the last adjoining rooms available. So, we felt stuck there nonetheless. Please provide some sort of explanation or compensation. Thank you!"
Ann 4-night trip
Posted 1 hour ago
Sheraton Mission Valley San Diego Hotel

Find out more about Central San Diego

Everything you need to know about Central San Diego vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Central San Diego vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Central San Diego vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Central San Diego vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Central San Diego. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Central San Diego in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $117 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Central San Diego rentals

At Expedia, we put the best Central San Diego vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Central San Diego rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Central San Diego vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Central San Diego. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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