Find luxury hotels in Depauw, IN

Start date: Check-in selected.
To Date
End date: Check-out

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Depauw Luxury Hotels

Our top choices for Depauw luxury hotels

Property entrance
The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (647)
"Have stayed here once before. Accommodations are wonderful and the sit down breakfast is lovely. Highly recommend this beautiful property."
United States
Kathy
$94 nightly
The price is $106
Dec 14 - Dec 15
Total with taxes and fees
The Pepin Mansion Historic B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Depauw Hotel Reviews

Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination

10/10 Excellent
"Yew"
Erik 1-night trip
Posted 4 days ago
Caesars Southern Indiana - A Caesars Rewards Destination

Frequently asked questions

Are you looking for a luxury hotel for your stay in Depauw?
Use Expedia to arrange your flight to Louisville Intl. Airport (SDF) airport or Louisville, KY (LOU-Bowman Field) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Depauw has to offer.
When can I expect good weather in Depauw?
Planning for the weather is an important factor for making your trip to Depauw a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 39°F. Average annual precipitation for Depauw is 55 inches.
What's there to see and do in Depauw?
Enjoy all that Depauw has to offer when you visit Marengo Cave National Landmark, Wyandotte Cave, and O'Bannon Woods State Park. If you have a little extra time during your trip, you might want to check out Corydon Capitol State Historic Site and Huber's Orchard, Winery & Vineyards.

Explore a world of travel with Expedia