Desco Vacations from $1,858

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Desco Vacation

Reserve a Desco vacation package and get ready to experience the best of this lively city. Consider staying in the neighborhood of San Simone, which is great for families, hiking and walking. During your trip to Desco, give yourself plenty of time for sightseeing. One of the best places to begin exploring is Fratelli Ciapponi. Don't delay visiting this destination any longer. The ultimate Desco vacation is just a few clicks away with Expedia.

The Latest Desco vacation packages

Price found within the past 48 hours. Click for updated prices.
Madrigale Panoramic Lifestyle & Soulful Hotel

Madrigale Panoramic Lifestyle & Soulful Hotel

4 out of 5
Price was $2,457, price is now $1,858 per person
$1,858
per person
Jul 26 - Aug 1
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to Milan (MXP)
9.2/10 Wonderful! (64 reviews)
Outstanding hotel, phenomenal food, pristine, modern roome with jaw dropping views . Spa and treatments were wonderful. So very very glad i booked here rather than in the aftual towns where its bustling with touriwts (which is nice but we wanted views and romance). Dont hesitate to book

Reviewed on Sep 13, 2025

Nuvole Garden Hotel

Nuvole Garden Hotel

5 out of 5
Save 100% on your flight
Price was $6,766, price is now $4,450 per person
$4,450
per person
Jun 13 - Jun 18
found 17 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Milan (MXP)
8.4/10 Very Good! (9 reviews)
Wonderful property with spectacular views.

Reviewed on Jul 4, 2025

Galleria Vik Milano - Townhouse Galleria - Small Luxury Hotels of the World

Galleria Vik Milano - Townhouse Galleria - Small Luxury Hotels of the World

5 out of 5
Milan Centre
Price was $2,673, price is now $1,997 per person
$1,997
per person
Jul 27 - Aug 1
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Milan (MXP)
8.4/10 Very Good! (325 reviews)
Room was spacious and bed was very comfortable. No refrigerator in the room or water. It was extremely noisy and difficult to sleep due to the noise at night and early in the morning. Location is central.

Reviewed on Apr 17, 2026

Hotel Ristorante Al Caminetto WorldHotels Crafted Adults Only

Hotel Ristorante Al Caminetto WorldHotels Crafted Adults Only

4 out of 5
Price was $3,080, price is now $2,312 per person
$2,312
per person
Jul 26 - Aug 1
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to Milan (MXP)
9.6/10 Exceptional! (36 reviews)
Highly recommend this hotel. Friendly stuff, clean, spacious and modern rooms. Parking space in front of the hotel.

Reviewed on Dec 2, 2024

Cape of Senses

Cape of Senses

5 out of 5
Save 100% on your flight
Price was $4,751, price is now $3,594 per person
$3,594
per person
Jul 26 - Aug 1
found 17 hours ago
Roundtrip flight included
Atlanta (ATL) to Milan (MXP)
9.2/10 Wonderful! (18 reviews)
Don't see what you're looking for?
See all available trips from Columbus to Desco
View all trips

What to do in Desco

Classic Rafting with Indomita

Classic Rafting with Indomita

$46
per adult
Classic Rafting with Indomita
Pizzoccheri food game with treasure hunt and cooking lesson

Pizzoccheri food game with treasure hunt and cooking lesson

$142
per adult
Pizzoccheri food game with treasure hunt and cooking lesson
Bernina Express Train

Lake Como, Bernina Express Train & St. Moritz - Full Day

$354
per adult
Lake Como, Bernina Express Train & St. Moritz - Full Day
See all activities in Desco

Desco Hotel Deals

Seven Park Hotel Lake Como - Adults Only

Seven Park Hotel Lake Como - Adults Only

4 out of 5
Via Montecchio Nord 21/A Colico LC
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $256 total per night from May 26 to May 27
$256 total
May 26 - May 27
Total with taxes and fees
9.2/10 Wonderful! (266 reviews)
Nice overall hotel, unfortunateky restaurant for dinner was not yet open so couldnt try. Staff were very friendly, rooms were clean and modern. Spa and saunas only opens from 4pm, wpuld have loved to use in the morning also but unfortunately only opens in afternoon. Breakfast was excellent!

Reviewed on Apr 24, 2026

Seven Park Hotel Lake Como - Adults Only
Hotel Regina

Hotel Regina

3 out of 5
Via Regina Levante 18 Gravedona CO
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $158 total per night from May 9 to May 10
$158 total
May 9 - May 10
Total with taxes and fees
9.4/10 Exceptional! (439 reviews)
Super kind staff and the food in the restaurant was delicious!

Reviewed on Apr 27, 2026

Hotel Regina
Hotel Beretta

Hotel Beretta

1 out of 5
Via per Esino 1 Perledo LC
Fully refundableReserve now, pay when you stay
$335 nightly
The price is $376 total per night from May 10 to May 11
$376 total
May 10 - May 11
Total with taxes and fees
8.6/10 Excellent! (179 reviews)
Great location, then have to walk too far to go to the train. Stop to go back to Milan. Everything I need was there.

Reviewed on Apr 22, 2026

Hotel Beretta
See all 2,788 properties in Desco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Desco Vacation Packages

Desco Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Population
130

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Desco vacation package cost?
You can pick up a vacation package to this top destination from $1,858 on Expedia. But how much your vacation to Desco costs will depend on your hotel choice, season and length of stay.
What are the cheapest months to go to Desco?
You can generally find lower rates and better availability in March, April and December. Explore our cheap Desco vacation packages and you could land some great off-season deals.
How many days is enough for Desco?
The ideal length for your Desco vacation depends on what you'd like to see and do. Usually, a handful of days to a week will give you plenty of time to tick off all the main attractions and discover some hidden spots along the way.
How to find the best Desco package deals?
Use Expedia's handy filters to help you find some tempting Desco package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your trip for midweek, or search for Desco package deals in the low season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package well in advance.
Is it cheaper to book a Desco vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your car rental, hotel and flight into one great-value price and you could save hundreds of dollars. You'll typically get a better deal than booking each component separately. And you'll still get the flexibility to create a customized Desco vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Desco?
If you're planning a spontaneous Desco adventure, browse our last-minute deals that can be booked up to one week before you take off. Don't want to leave things to the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Desco vacation packages?
Your Desco trip should be a relaxing escape from your daily routine, not a source of money-related stress. So to give you extra flexibility, we've joined up with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.