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Greenville Vacation Rentals

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    Check prices for these dates, December 14 – 15, 2026

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    Our top choices for Greenville vacation rentals

    1. Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!

    A fire pit with four Adirondack chairs around it, set in a forested area.

    2. Unique apartment in historic downtown

    A white building with a number '308' and a logo on the door.

    3. Unique loft in historic downtown

    A spacious room with a brick wall, a large bed, a ceiling fan, and two wicker lamps.

    4. Edwards House; Litchfield, IL; Pets welcome

    A modern kitchen with white cabinets, a gas stove, and a microwave. There is a dining area with a wooden table and two chairs.

    5. Route 66 house; Litchfield IL; Pets welcome

    A modern kitchen with a dark wood floor, a white cabinet, a black bar stool, and a wooden table.

    6. Harrison House; Litchfield, IL; Pets welcome

    A room with a wooden floor, a sliding glass door leading to an outdoor patio with a table and chairs, and a broom leaning against the wall.

    7. State Street House; 3-br house; PETS WELCOME; Litchfield

    A modern kitchen with white cabinets, a dark wooden countertop, and a stainless steel sink.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Top Greenville Hotel Reviews

    Comfort Inn & Suites Greenville I-70

    A hotel reception area with a computer desk, a printer, a coffee machine, and a framed cityscape picture on the wall.

    Super 8 by Wyndham Greenville

    A breakfast area with a counter, microwave, coffee machine, and seating.

    SureStay Hotel by Best Western Greenville

    An indoor swimming pool with a blue shark float, lounge chairs, and a lifeguard stand.

    Holiday Inn Express & Suites Litchfield West by IHG

    A Holiday Inn Express & Suites building with a covered entrance and a landscaped area with plants and rocks.

    Best Western Plus Centralia Hotel & Suites

    A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

    Holiday Inn Express & Suites Vandalia by IHG

    A Holiday Inn Express & Suites hotel with a brick facade and a covered entrance.

    Hampton Inn by Hilton Litchfield

    A Hampton Inn hotel with a flagpole, clear signage, and a well-maintained lawn.

    Lighthouse Lodge

    A white door with the number 16, a mailbox, and a small light fixture on the left.

    Super 8 by Wyndham Staunton

    A modern living room with patterned carpet, two sofas, a coffee table, and a TV.

    Quality Inn Litchfield Route 66

    A spacious living room with a fireplace, a television, and a modern chandelier.

    Quality Inn & Suites Vandalia near I-70 and Hwy 51

    A modern lobby with a stone accent wall, a flat-screen TV, orange armchairs, a dark sofa, and a colorful rug.

    Baymont by Wyndham Litchfield

    A hotel lobby with a check-in counter, seating area with tables and chairs, and a fireplace.

    Seasons Inn & Suites Highland

    A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.

    Ramada by Wyndham Vandalia

    A lobby with a wooden staircase, a desk with a computer, and patterned armchairs.

    Americas Best Value Inn Vandalia

    A restaurant with a bar area, seating, and a view of the outside.

    Innkeeper Motel

    A riverside view with a gravel path and a building with a red facade.

    Find out more about Greenville

    Everything you need to know about Greenville vacation rentals

    Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Greenville vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

    There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Greenville vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

    Greenville vacation rentals: An excellent choice for every season

    Whenever you want to travel, a warm welcome awaits you in Greenville. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Greenville in high season.

    Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $115 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

    How to find incredible deals on Greenville rentals

    At Expedia, we put the best Greenville vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

    To find some top Greenville rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Greenville vacation.

    If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Greenville. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

    Frequently Asked Questions

    Can I find a vacation rental in Greenville?

    Yes, you can find vacation rentals close to top points of interest in Greenville, or you can choose a secluded option if you're looking for a relaxing stay. Our travelers say Greenville has a good selection of restaurants. Make sure you have time to check out the golf courses while you're in the area.

    What's the top vacation rental that Greenville has to offer?

    Private 7-Acre Multi Family Retreat Perfect for Reunions or Other Venues: This Greenville vacation home rental offers an outdoor pool, a fireplace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a balcony and a selection of games. Other favorite homes for rent in Greenville are THE NEST getaways&gatherings, beach/lake sleeps 20+ and The Beaumont Suite !.

    How many vacation rentals are there in Greenville?

    With 5 Expedia vacation rentals, you're sure to find just the right place for your Greenville stay.

    What can I see and do in Greenville?

    While you're exploring the area, Carlyle Lake and Silver Lake Park are a couple of picturesque spots to get outside and enjoy nature. While here, Greenville Country Club and Patriot's Park are other places worth a visit.

    What are vacation rentals like in Greenville?

    Vacation rentals are privately owned properties you can book for a couple days or more in Greenville. Vacation rentals offer extras like kitchens and laundry facilities so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of privacy away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also get more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great option for a family getaway.

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