Title: Secure Isla Grande Vacation Packages | Explore Grande Island 2026 | Expedia.com [Isla Grande Travel Guide](https://expedia.com/Isla-Grande.dx6053183)[Hotels in Isla Grande](https://expedia.com/Isla-Grande-Hotels.d6053183.Travel-Guide-Hotels)[Vacation Rentals in Isla Grande](https://expedia.com/Isla-Grande-Vacation-Rentals.d6053183.Travel-Guide-VacationRentals)[Flights to Isla Grande](https://expedia.com/Cheap-Flights-To-Isla-Grande.d6053183.Travel-Guide-Flights)[Things to do in Isla Grande](https://expedia.com/Things-To-Do-In-Isla-Grande.d6053183.Travel-Guide-Activities)[Car Rentals in Isla Grande](https://expedia.com/Car-Rentals-In-Isla-Grande.d6053183.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6053183/3ddb22e8-2245-453b-b3ca-3467e9b3943f.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Isla Grande Vacations from $618 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Isla Grande Vacation With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like [Isla Mamey](https://www.expedia.com/Isla-Mamey-Colon.d553248623454093160.Vacation-Attraction) and [Portobelo National Park](https://www.expedia.com/Portobelo-National-Park-Colon.d6252836.Vacation-Attraction). Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia. ## The Latest Isla Grande vacation packages Price found within the past 48 hours. Click for updated prices. ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites $618 per person Apr 19 - Apr 24 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 10/10 Exceptional! (1 review) Excellent apartment on a golf resort. 5 Star. Reviewed on Jan 28, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight $1,029 per person Apr 19 - Apr 24 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) The room had no window to the outside it instead had a large window into an interior hall. Maid service was inconsistent. Breakfast was not a good value. Reviewed on Feb 5, 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco Save 100% on your flight $1,006 per person Apr 27 - May 2 found 14 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) Nice hotel. Friendly staff Reviewed on Feb 9, 2026 ![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Villa Botero By Casa Mojito B&B $944 per person Mar 29 - Apr 4 found 1 day ago Roundtrip flight included New York (NYC) to Panama City (PTY) 9.8/10 Exceptional! (60 reviews) We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time. Reviewed on Jan 22, 2026 ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $771 per person Mar 14 - Mar 18 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) Very nice and clean hotel. Excellent breakfast which was included. We will return Reviewed on Feb 12, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla Grande [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-12/2026-03-19/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_6053183) ## Isla Grande Hotel Deals ![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### HOTEL ISLA GRANDE Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province 4.8/10 (6 reviews) This hotel is very run down, and should not be $150/night. Did not have access to running water in our room. Location and beach are its saving graces. Reviewed on Feb 4, 2026 [Get rates](https://expedia.com/Hotel-Search?startDate=2%2F26%2F2026&endDate=2%2F27%2F2026&selected=119947185&PinnedHotelID=119947185&HadPinnedHotel=true®ionId=6053183) [](https://expedia.com/Hotel-Search?startDate=2%2F26%2F2026&endDate=2%2F27%2F2026&selected=119947185&PinnedHotelID=119947185&HadPinnedHotel=true®ionId=6053183) ![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Cocotal La Guaira Isla Grande Provincia de Colón Fully refundableReserve now, pay when you stay $103 nightly $114 total Feb 17 - Feb 18 Total with taxes and fees 9/10 Wonderful! (7 reviews) The bed is terrible, The Bathroom is terrible. Hotel is in terrible condition. Needs work. If you are on 2nd or 3 rd floor the stairs are terrible. Restaurant is good. Reviewed on Feb 4, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F17%2F2026&endDate=2%2F18%2F2026&selected=116789972&PinnedHotelID=116789972&HadPinnedHotel=true®ionId=6053183) ![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/4a052041_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ordovician Beach Resort Isla Grande Isla Grande Colon $465 nightly $515 total Feb 23 - Feb 24 Total with taxes and fees 10/10 Exceptional! (8 reviews) The best service in Panama!!! We truly felt cared for in every detail — the team is attentive, warm, and genuinely professional. The food was outstanding: the chef is exceptional! Every dish reflected passion, quality, and pride. This hotel is located on a beautiful Caribbean island, surrounded by ... Reviewed on Jan 31, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F23%2F2026&endDate=2%2F24%2F2026&selected=103761591&PinnedHotelID=103761591&HadPinnedHotel=true®ionId=6053183) [See all 55 properties in Isla Grande](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F13%2F2026&endDate=2%2F14%2F2026®ionId=6053183) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Isla Grande Vacation Packages ## Isla Grande Essential Information | Language | Spanish | | --------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Panamanian balboas | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Max Temp Winter | 80ºF | | Max Temp Summer | 85ºF | | Top Sights | [Blanca Beach](https://www.expedia.com/Blanca-Beach-Portobelo.d6286205.Vacation-Attraction), [Portobelo National Park](https://www.expedia.com/Portobelo-National-Park-Colon.d6252836.Vacation-Attraction) and [Mirador Perú](https://www.expedia.com/Mirador-Peru-Portobelo.d553248621532964859.Vacation-Attraction) | ## More vacations you might like 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Pick your dates: What you'd like to do in Isla Grande and your preferred season will help you decide when to get away. > 2. Set a budget: Consider expenses such as transportation, flights and meals when calculating how much to save for your trip to Isla Grande. Then, select a hotel that fits your budget, whether that's a wallet-friendly option or a lavish getaway. > 3. Use Expedia's [trip planning tool](https://www.expedia.com/why/trip-planning) to discover Isla Grande: Research every part of your trip to Isla Grande with this handy planner. Invite family or friends to collaborate on a group getaway, search for stays or things to do and make bookings. > 4. Decide how long to go away for: Now that you know more about Isla Grande, you can work out the ideal length of your vacation. Put together a draft itinerary and give yourself enough time to cover everything you want to see. > 5. Bundle your airfare and accommodations: Once you've settled on your dates and duration, book the perfect Isla Grande vacation package for you. > 6. Book any day trips or activities: Now to the fun part — organizing everything you want to do and see. Explore some of the exciting [things to do in Isla Grande](https://www.expedia.com/Things-To-Do-In-Isla-Grande.d6053183.Travel-Guide-Activities) and reserve your tickets early to save time (and maybe some cash too!). ### Does Expedia offer Book Now, Pay Later Isla Grande vacation packages? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [La Guaira Hotels ](https://www.expedia.com/La-Guaira-Hotels.d3000439511.Travel-Guide-Hotels) - [4 Star Hotels in La Guaira ](https://www.expedia.com/4Star-La-Guaira-Hotels.s40-0-d3000439511.Travel-Guide-Filter-Hotels) - [3 Star Hotels in La Guaira ](https://www.expedia.com/3Star-La-Guaira-Hotels.s30-0-d3000439511.Travel-Guide-Filter-Hotels) - [5 Star Hotels in La Guaira ](https://www.expedia.com/5Star-La-Guaira-Hotels.s50-0-d3000439511.Travel-Guide-Filter-Hotels) - [Hotels near Portobelo National Park ](https://www.expedia.com/Portobelo-National-Park-Hotels.0-l6252836-0.Travel-Guide-Filter-Hotels) - [Puerto Lindo Hotels ](https://www.expedia.com/Puerto-Lindo-Hotels.d3000007427.Travel-Guide-Hotels) - [Lodges in Puerto Lindo ](https://www.expedia.com/Puerto-Lindo-Lodges.d3000007427-aaLodges.Travel-Guide-Accommodation) - [Hotels near Isla Mamey ](https://www.expedia.com/Isla-Mamey-Hotels.0-l553248623454093160-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Cacique ](https://www.expedia.com/4Star-Cacique-Hotels.s40-0-d553248635975858719.Travel-Guide-Filter-Hotels) - [Hotels near Blanca Beach ](https://www.expedia.com/Blanca-Beach-Hotels.0-l6286205-0.Travel-Guide-Filter-Hotels) - [Nombre de Dios Hotels ](https://www.expedia.com/Nombre-De-Dios-Hotels.d3000462548.Travel-Guide-Hotels) - [Vacation Homes in Nombre de Dios ](https://www.expedia.com/Nombre-De-Dios-Private-Vacation-Homes.d3000462548-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [3 Star Hotels in Nombre de Dios ](https://www.expedia.com/3Star-Nombre-De-Dios-Hotels.s30-0-d3000462548.Travel-Guide-Filter-Hotels) - [Hotels near San Felipe Church ](https://www.expedia.com/San-Felipe-Church-Hotels.0-l6253121-0.Travel-Guide-Filter-Hotels) - [Guest Houses in Puerto Lindo ](https://www.expedia.com/Puerto-Lindo-Guest-Houses.d3000007427-aaGuestHouses.Travel-Guide-Accommodation) - [Villas in Nombre de Dios ](https://www.expedia.com/Nombre-De-Dios-Villas.d3000462548-aaVillas.Travel-Guide-Accommodation) - [Hostels in La Guaira ](https://www.expedia.com/La-Guaira-Hostels.d3000439511-aaHostels.Travel-Guide-Accommodation) - [Cacique Hotels ](https://www.expedia.com/Cacique-Hotels.d553248635975858719.Travel-Guide-Hotels) - [Hotels near Real Aduana de Portobelo ](https://www.expedia.com/Real-Aduana-De-Portobelo-Hotels.0-l553248621532964863-0.Travel-Guide-Filter-Hotels) - [Apartments in La Guaira ](https://www.expedia.com/La-Guaira-Apartments.d3000439511-aaApartments.Travel-Guide-Accommodation) - [Villas in Puerto Lindo ](https://www.expedia.com/Puerto-Lindo-Villas.d3000007427-aaVillas.Travel-Guide-Accommodation) - [Hotels near Fuerte San Jerónimo ](https://www.expedia.com/Fuerte-San-Jeronimo-Hotels.0-l553248621532964862-0.Travel-Guide-Filter-Hotels) - 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[Car rentals near Isla Mamey ](https://www.expedia.com/Car-Rentals-In-Isla-Mamey.d553248623454093160.Car-Rental-Guide) - [Car rentals near Nombre de Dios ](https://www.expedia.com/Car-Rentals-In-Nombre-De-Dios.d3000462548.Car-Rental-Guide) - [Thrifty EU Rental Cars in Puerto Lindo ](https://www.expedia.com/Thrifty-EU-Car-Rentals-In-Puerto-Lindo.d3000007427-c1055.Car-Rental-Guide-Suppliers) - [Rent A Wreck Rental Cars in Puerto Lindo ](https://www.expedia.com/Rent-A-Wreck-Car-Rentals-In-Puerto-Lindo.d3000007427-c33.Car-Rental-Guide-Suppliers) - [Localiza Argentina Rental Cars in Puerto Lindo ](https://www.expedia.com/Localiza-Argentina-Car-Rentals-In-Puerto-Lindo.d3000007427-c1097.Car-Rental-Guide-Suppliers) - [Car rentals near San Felipe Church ](https://www.expedia.com/Car-Rentals-In-San-Felipe-Church.d6253121.Car-Rental-Guide) - [Car rentals near Fuerte San Jerónimo ](https://www.expedia.com/Car-Rentals-In-Fuerte-San-Jeronimo.d553248621532964862.Car-Rental-Guide) - [Things to do in Puerto Lindo ](https://www.expedia.com/Things-To-Do-In-Puerto-Lindo.d3000007427.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app