
Isla Grande Vacations from $694
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Your Isla Grande Vacation
With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like Isla Mamey and Portobelo National Park. Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia.
The Latest Isla Grande vacation packages
Price found within the past 48 hours. Click for updated prices.

Mahogany Suites
Price was $1,091, price is now $694 per person
$694
per person
Jun 10 - Jun 14
found 24 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.4/10 Exceptional! (6 reviews)
This is a very nice gated country club. It has great amenities and the apartment is in excellent condition and very comfortable. We only had one issue and that was with the dryer not working, which we didn’t discover until we had already washed a load of clothes. There isn’t a lobby that is staffed at this location, and it’s not clear who to contact with issues. The “check-in” occurred at the security gate as you arrive to the country club. But despite the lack of clear instructions you get when booking, I still recommend this place, especially if you have more than a one night stay, and would stay here again.
Reviewed on Mar 16, 2026

Central Hotel Panama Casco Viejo
Casco Viejo
Price was $1,298, price is now $976 per person
$976
per person
Jun 9 - Jun 12
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (1,000 reviews)
Breakfast was good, staff friendly, good selection.
Reviewed on Apr 2, 2026


Dreams Playa Bonita Panama - All Inclusive
Price was $1,744, price is now $1,342 per person
$1,342
per person
Jun 17 - Jun 22
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
7.6/10 Good! (1,000 reviews)
Place is great and staff is awesome
Reviewed on Apr 3, 2026

Megapolis Hotel Panamá
San Francisco
Price was $1,137, price is now $876 per person
$876
per person
Jun 9 - Jun 12
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.4/10 Very Good! (1,482 reviews)
The breakfast was very fresh and delicious, there were lots of options
Reviewed on Apr 3, 2026
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Ordovician Beach Resort
Isla Grande Isla Grande Colon
$719 nightly
The price is $799 total per night from Apr 25 to Apr 26
$799 total
Apr 25 - Apr 26
Total with taxes and fees
10/10 Exceptional! (9 reviews)
The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed.
Reviewed on Feb 21, 2026

HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
$105 nightly
The price is $115 total per night from Apr 11 to Apr 12
$115 total
Apr 11 - Apr 12
Total with taxes and fees
4.8/10 (8 reviews)
This hotel is very run down, and should not be $150/night. Did not have access to running water in our room. Location and beach are its saving graces.
Reviewed on Feb 4, 2026

Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $114 total per night from Apr 15 to Apr 16
$114 total
Apr 15 - Apr 16
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Isla Grande Vacation Packages
Isla Grande Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Max Temp Winter | 80ºF |
Max Temp Summer | 85ºF |
Top Sights | Blanca Beach, Portobelo National Park and Mirador Perú |
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