
Isla Grande Vacations from $694
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Your Isla Grande Vacation
With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like Isla Mamey and Portobelo National Park. Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia.
The Latest Isla Grande vacation packages
Price found within the past 48 hours. Click for updated prices.

Mahogany Suites
Price was $1,091, price is now $694 per person
$694
per person
Jun 10 - Jun 14
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.4/10 Exceptional! (6 reviews)
This is a very nice gated country club. It has great amenities and the apartment is in excellent condition and very comfortable. We only had one issue and that was with the dryer not working, which we didn’t discover until we had already washed a load of clothes. There isn’t a lobby that is staffed at this location, and it’s not clear who to contact with issues. The “check-in” occurred at the security gate as you arrive to the country club. But despite the lack of clear instructions you get when booking, I still recommend this place, especially if you have more than a one night stay, and would stay here again.
Reviewed on Mar 16, 2026

Villa Botero By Casa Mojito B&B
Price was $1,119, price is now $722 per person
$722
per person
May 3 - May 9
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
9.8/10 Exceptional! (64 reviews)
excellent breakfast every day and varied menu. nice room, had a a fridge and coffee maker, sitting area and very clean pool. walkable to beach and few restaurants - beach was very nice.
Reviewed on Mar 22, 2026

Hotel Plaza Herrera
Casco Viejo
Price was $1,568, price is now $1,043 per person
$1,043
per person
May 13 - May 17
found 1 day ago
Roundtrip flight included
Georgetown (GEO) to Panama City (PTY)
9.8/10 Exceptional! (26 reviews)
Internet was good. Suite was spacious. Shower and clothing closet on a seperate floor from bedroom. Ceiling fan was quiet and finctioning. A/C also quiet and functioning. Deck fan operates on a chain that was to short. Hammock on the deck takes alot of space where some decent seating and a small table might be. Great view of the park and street activity. Location is not know to Uber. Early morning coffee is available. Paid for morning breakfast with room online ... used 1 of 2 breakfasts, no credit offered. Breakfast quality is reasonable and tasted good. Staff are probably best asset at this property. They try very hard to make guests welcome amd comfortable. I did not feel like was being worked for an expected tip at all.
Reviewed on Mar 24, 2026


Central Hotel Panama Casco Viejo
Casco Viejo
Price was $1,492, price is now $1,064 per person
$1,064
per person
Jun 10 - Jun 14
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (1,000 reviews)
Breakfast was good, staff friendly, good selection.
Reviewed on Apr 2, 2026
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Ordovician Beach Resort
Isla Grande Isla Grande Colon
$719 nightly
The price is $799 total per night from Apr 9 to Apr 10
$799 total
Apr 9 - Apr 10
Total with taxes and fees
10/10 Exceptional! (9 reviews)
The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed.
Reviewed on Feb 21, 2026

HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
$105 nightly
The price is $115 total per night from Apr 11 to Apr 12
$115 total
Apr 11 - Apr 12
Total with taxes and fees
4.8/10 (8 reviews)
This hotel is very run down, and should not be $150/night. Did not have access to running water in our room. Location and beach are its saving graces.
Reviewed on Feb 4, 2026

Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $108 total per night from Apr 6 to Apr 7
$108 total
Apr 6 - Apr 7
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Isla Grande Vacation Packages
Isla Grande Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Max Temp Winter | 80ºF |
Max Temp Summer | 85ºF |
Top Sights | Blanca Beach, Portobelo National Park and Mirador Perú |
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