
Isla Grande Vacations from $726
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Your Isla Grande Vacation
With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like Isla Mamey and Portobelo National Park. Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia.
The Latest Isla Grande vacation packages
Price found within the past 48 hours. Click for updated prices.

Mahogany Suites
Price was $1,122, price is now $726 per person
$726
per person
May 13 - May 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.4/10 Exceptional! (6 reviews)
This is a very nice gated country club. It has great amenities and the apartment is in excellent condition and very comfortable. We only had one issue and that was with the dryer not working, which we didn’t discover until we had already washed a load of clothes. There isn’t a lobby that is staffed at this location, and it’s not clear who to contact with issues. The “check-in” occurred at the security gate as you arrive to the country club. But despite the lack of clear instructions you get when booking, I still recommend this place, especially if you have more than a one night stay, and would stay here again.
Reviewed on Mar 16, 2026

Central Hotel Panama Casco Viejo
Casco Viejo
Price was $2,204, price is now $1,546 per person
$1,546
per person
Apr 22 - Apr 28
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (1,000 reviews)
Such a beautiful hotel!!! I chose it because of the stair case but was floored when I saw it in person. Gorgeous, peaceful.It was a dream fantasy come to fruition!!! The location perfect. Few feet away from the presidential plaza. There was something happening everyday right outside the hotel all the time. The staff so welcoming, breakfast was delicious. The city the people. I cannot say enough Panama and its people. So welcoming. I will definitely stay there again and longer. It was like staying in a movie. I see why our people move there and why citizens rarely move out this country
Reviewed on Mar 20, 2026

Hotel Riu Plaza Panama
Bella Vista
Price was $1,460, price is now $1,087 per person
$1,087
per person
Apr 22 - Apr 28
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (5,100 reviews)
Great location. Staff is not cordial. Great breakfast
Reviewed on Mar 22, 2026


Hotel La Compania Del Valle
Price was $1,708, price is now $1,333 per person
$1,333
per person
May 30 - Jun 6
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.8/10 Exceptional! (97 reviews)
Brand new property with clean spacious rooms. Ample storage in the room and large bathroom with walk in shower and Molton brown toiletries. There was complimentary bottled water although the tap water is safe to drink, and 6 complimentary coffee pods a day. The yoga instructor was excellent and the yoga was complimentary 9am Thursday to Monday on a roof terrace on the spa. There is a roof terrace bar with amazing views of the surrounding mountains with complimentary drinks for guests each evening 5pm to 7pm which was a really nice touch. All the staff are professional and friendly. The breakfasts are excellent quality and lots of variety. The dinners in the terra vegetarian restaurant and tempo restaurants were excellent quality. We didn’t eat in fuego so can’t comment on that. The food prices are at the higher end but all great quality. We paid around $70-80 for 2 people for 2 courses each and 1 drink each. Our only criticism was the room rate included breakfast however we were charged extra ($30 for 2) for a takeout breakfast on the day we had an early pick up for a trip out with a guide which was a bit steep given the room rate. There were lots of birds in the area and the hotel could attract many to the gardens/grounds if the hummingbird feeders were regularly replenished (they were practically empty our full 5 day stay). A suggestion would be to use up any left over fruit such as papaya or banana to set up a feeding station for wild birds in the hotel gardens
Reviewed on Mar 20, 2026
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Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $114 total per night from Mar 31 to Apr 1
$114 total
Mar 31 - Apr 1
Total with taxes and fees

HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
4.8/10 (8 reviews)
This hotel is very run down, and should not be $150/night. Did not have access to running water in our room. Location and beach are its saving graces.
Reviewed on Feb 4, 2026

Ordovician Beach Resort
Isla Grande Isla Grande Colon
$450 nightly
The price is $500 total per night from Apr 7 to Apr 8
$500 total
Apr 7 - Apr 8
Total with taxes and fees
10/10 Exceptional! (9 reviews)
The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed.
Reviewed on Feb 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Isla Grande Vacation Packages
Isla Grande Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Max Temp Winter | 80ºF |
Max Temp Summer | 85ºF |
Top Sights | Blanca Beach, Portobelo National Park and Mirador Perú |
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