
Santa Cruz Island Vacations from $463
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The Latest Santa Cruz Island vacation packages
Price found within the past 48 hours. Click for updated prices.

Natura Gardens Galápagos Hotel
Price was $636, price is now $463 per person
$463
per person
Jan 2 - Jan 6
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
7.6/10 Good! (4 reviews)
One of three days water in entire building was shut off. Had to wait for several hours for water to return. Though Owner and family are very nice people
Reviewed on Sep 22, 2025

Angermeyer Waterfront Inn
Price was $834, price is now $586 per person
$586
per person
Nov 9 - Nov 12
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
9.4/10 Exceptional! (121 reviews)
Beautiful view and very friendly staff. You do have to take a water taxi ($1 and operates 24/7) to the main part of downtown Santa Cruz but the view is worth it! Also it’s across from The Point by Midoro which as an amazing view and food. I would stay there again!
Reviewed on Aug 26, 2025


Blu Galapagos Sustainable Waterfront Lodge
Save 100% on your flight
Price was $1,563, price is now $1,133 per person
$1,133
per person
Jan 2 - Jan 6
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
8.8/10 Excellent! (115 reviews)
I stayed in the Wolf suite- BEST view on the island! It was dreamy… the restaurant smells were great and made me hungry… the restaurant itself,(not associated with the hotel) meh. The staff was friendly, but they want to make money off of you- so save your money and go into the town and book your own activities. You’ll save a ton of money. But I liked this place. Very accommodating. It was a little noisy- lots of birds in the rafters and lizards coming in and out… but I actually enjoyed them. I had ample hot water - the best shower! Definitely a suite for lovers although I didn’t have one with me- it left me wishing I did.
Reviewed on Oct 1, 2025

Royal Palm Galapagos, Curio Collection Hotel by Hilton
Save 100% on your flight
Price was $1,635, price is now $1,226 per person
$1,226
per person
Jan 2 - Jan 6
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
9.2/10 Wonderful! (51 reviews)
The best part about staying at Royal Palms Galapagos was the staff. They were all friendly and helpful, making their best effort to make our stay enjoyable. They remembered our dietary restrictions and would point out if a dish had food we couldn’t eat.
The facilities were very nice, and cleaned by friendly staff. The property grounds were serene and lovely. We thoroughly enjoyed our visit and would definitely choose the Royal Palms again.
Reviewed on Sep 13, 2025
Don't see what you're looking for?
See all available trips from Des Moines to Santa Cruz Island
View all tripsDiscover the most popular places to visit in Santa Cruz Island

Tortuga Bay Beach
If a restful vacation is part of your travel plans, Tortuga Bay Beach might be the perfect place to seek out during your trip to Bella Vista. While you're in the area, wander around the parks.

El Garrapatero Beach
Why not spend a carefree afternoon at El Garrapatero Beach during your travels in El Cascajo? While you're in the area, wander around the parks.

Las Ninfas Lagoon
Commune with nature and explore the great outdoors at Las Ninfas Lagoon during your travels in Puerto Ayora. While you're here, you can savor the top-notch restaurants.
What to do in Santa Cruz Island

El Chato 2 Reserve Admission Ticket in Santa Cruz Island
$8
per traveler

Full Day Tour Pinzon Island + La Fe/Las Palmas - Snorkeling & Fishing
$169
per adult
80% of travellers recommend
Santa Cruz Island Hotel Deals

Hotel Fiesta
Calle Moises Brito y Juan Montalvo, Puerto Ayora, Galapagos
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $155 total per night from Oct 10 to Oct 11
$155 total
Oct 10 - Oct 11
9/10 Wonderful! (368 reviews)
"The rooms were very comfortable, the jacuzzi was a very nice surprise for us, the weather was a bit cold so we had a very good time there. It has a very convenient location you can walk to many places. The breakfast was very good and the staff was very kind."
Reviewed on Sep 17, 2025

Hotel el descanso del Guia
Calle Delfin, Barrio el Mirador, Puerto Ayora, Galapagos
$71 nightly
The price is $71 total per night from Oct 12 to Oct 13
$71 total
Oct 12 - Oct 13
8.6/10 Excellent! (168 reviews)
"Muy lindo todo <3"
Reviewed on Aug 19, 2025

Finch Bay Galapagos Hotel
Barrio Punta Estrada, Puerto Ayora, Galapagos
$522 nightly
The price is $579 total per night from Nov 8 to Nov 9
$579 total
Nov 8 - Nov 9
9.2/10 Wonderful! (87 reviews)
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"
Reviewed on Dec 31, 2024
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santa Cruz Island Essential Information
Language | Spanish |
---|---|
Currency | U.S dollars |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Seymour Airport (GPS) |
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.