Title: Santa Fe Island Vacation Rentals from $76: Search Short-Term Rentals | Expedia.com

[Santa Fe Island Travel Guide](https://expedia.com/Santa-Fe-Island.dx6336630)[Hotels in Santa Fe Island](https://expedia.com/Santa-Fe-Island-Hotels.d6336630.Travel-Guide-Hotels)[Flights to Santa Fe Island](https://expedia.com/Cheap-Flights-To-Santa-Fe-Island.d6336630.Travel-Guide-Flights)[Car Rentals in Santa Fe Island](https://expedia.com/Car-Rentals-In-Santa-Fe-Island.d6336630.Car-Rental-Guide)[Santa Fe Island Vacation Packages](https://expedia.com/Santa-Fe-Island.d6336630.Destination-Travel-Guides)

![Seal lions 😍 #aquatrove](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Elizabeth Oates

![](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

## Check prices for these dates

In two weeks

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6336630&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=6336630&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=6336630&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 3 - Jul 5](https://www.expedia.com/Hotel-Search?regionId=6336630&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Fe Island vacation rentals

![Family Duplex, 2 Bedrooms, Private Bathroom, Garden View (Courtyard ) | Terrace/patio](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/ffb9bce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Ensuite (One bedroom King) | Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/34c553bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/392aa62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/aabb8b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Boutique-Suites.h16786878.Hotel-Information)

9.2/10

Wonderful

(20 reviews)

"Very nice suite, clean, quiet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Masoud

$114 nightly

$114 total

Mar 13 - Mar 14

[](https://www.expedia.com/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Boutique-Suites.h16786878.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/9468ea94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Quadruple Room, 1 Bedroom | 1 bedroom, down comforters, individually furnished, blackout drapes](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/95d1d08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/e9355473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Quadruple Room, 1 Bedroom | Private kitchen | Fridge, oven, rice cooker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/7ebdf614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites.h34937768.Hotel-Information)

9.4/10

Exceptional

(24 reviews)

"Check was early and friendly staff Room was super clean and comfortable"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judy

$92 nightly

$92 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites.h34937768.Hotel-Information)

![Luxury Apartment, Balcony | Living area | LCD TV, Netflix, pay movies, streaming services](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/39eae50b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment, Balcony | Living area | LCD TV, Netflix, pay movies, streaming services](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/7209e130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment, Balcony | Balcony](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/992ac688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, Balcony, City View | Balcony](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/5efe3e57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galapagos-Coliving-Ecuador-Casa-Tuna.h106882041.Hotel-Information)

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galapagos-Coliving-Ecuador-Casa-Tuna.h106882041.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/a58537c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/9e01f48f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/b8157967.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/d3c64b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Queen-Bedroom-Suite-ON-THE-Second-High-Floor-AT-Arianas-Galapagos-Hostal.h102780548.Hotel-Information)

$69 nightly

$76 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-Queen-Bedroom-Suite-ON-THE-Second-High-Floor-AT-Arianas-Galapagos-Hostal.h102780548.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/e27d3e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/cc3d7388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/735d660b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/41f41cf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Bienvenido-A-Tu-Hogar-Isleno-En-Galapagos.h100177018.Hotel-Information)

$102 nightly

$102 total

Apr 7 - Apr 8

[](https://www.expedia.com/Puerto-Ayora-Hotels-Bienvenido-A-Tu-Hogar-Isleno-En-Galapagos.h100177018.Hotel-Information)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f0249e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/5b0760b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, coffee/tea maker, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/6f52aa05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f1c0fb19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information)

10/10

Exceptional

(1 review)

"Nice and beautiful house to stay very impressed "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

$121 nightly

$121 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/0d9fc98c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/236b5ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/2d5538fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, coffee/tea maker, cookware/dishes/utensils, lobster pot](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/80603d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in PUERTO AYORA SANTA CRUZ GALAPAGOS

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites-Cerca-Del-Mar.h50883187.Hotel-Information)

8.8/10

Excellent

(5 reviews)

"Really nice place!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sefora

$130 nightly

$170 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites-Cerca-Del-Mar.h50883187.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/1f94b12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2ad1a614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/369f220c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Townhome, 1 Bedroom, Non Smoking, City View | Living area](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/50aec426.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information)

6.0/10

(1 review)

"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"

![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg)

アオアシカツオドリ

[](https://www.expedia.com/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information)

![1 bedroom, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/1213239e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dishwasher, cookware/dishes/utensils, dining tables](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/3829be13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/3ed3ea89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/b1d46278.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Island-Apartments.h59677109.Hotel-Information)

$115 nightly

$115 total

Apr 1 - Apr 2

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Island-Apartments.h59677109.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/ebf60a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/d7cc9d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/b574e039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/46b3f49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information)

10/10

Exceptional

(1 review)

"We stayed 3 nights in the "casa grande" associated with the Galapagos Pearl Hotel and could not have been more pleased. The casa has 2 bedrooms, a small kitchen, one bathroom, and is conveniently located right next to the pool and the outdoor dining area where Yolanda serves breakfast. Your room is cleaned every day. The garden surrounding the pool and casa is lush and full of geckos, cats, and beautiful plantings. Yolanda is from the Galapagos, she is a wonderful host and her daughter helped us...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura E.

$227 nightly

$251 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information)

![1 bedroom, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/fae3fe2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/c1ad2cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/f6bbb628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/9ae4b365.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Serve-You-With-Quality-And-Warmth-In-Your-Home.h60597196.Hotel-Information)

$99 nightly

$99 total

Apr 1 - Apr 2

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Serve-You-With-Quality-And-Warmth-In-Your-Home.h60597196.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/e9b7ef2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/4776976b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/8b0d2620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/a5ec6899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h110134025.Hotel-Information)

10/10

Exceptional

(1 review)

"Perfect start to finish. Very clean! Drinking water provided. The host helped us with a small hiccup regarding our transfer so we were able to catch the ferry to San Cristóbal with no problem. Highly recommend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shannyn Z.

$90 nightly

$90 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h110134025.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/9465b582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, stovetop, coffee/tea maker, blender](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/a87cb59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/343f2f1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/5328eb63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h102721840.Hotel-Information)

10/10

Exceptional

(1 review)

"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Dean P.

$89 nightly

$99 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h102721840.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/102000000/101500000/101495500/101495451/fdcabf70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/102000000/101500000/101495500/101495451/d15e7d32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101500000/101495500/101495451/f2ee306a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101500000/101495500/101495451/ea0beeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Panoramic-Rooms-At-Galapagos-Verde-Azul.h101495451.Hotel-Information)

$200 nightly

$227 total

Mar 13 - Mar 14

[](https://www.expedia.com/Puerto-Ayora-Hotels-Panoramic-Rooms-At-Galapagos-Verde-Azul.h101495451.Hotel-Information)

![1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/82ca6a97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/c896c6c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/4b47b389.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/a7583985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Servirle-Con-Calidad-Y-Calidez-En-Su-Casa.h59688686.Hotel-Information)

$49 nightly

$49 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Servirle-Con-Calidad-Y-Calidez-En-Su-Casa.h59688686.Hotel-Information)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/c866cc9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/c0869485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/43162e8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/125000000/124400000/124393500/124393435/5e3e1504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h124393435.Hotel-Information)

$316 nightly

$355 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h124393435.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/ac8a7bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/ee9d32a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/4e605901.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/3200cd5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-2-Bedroom-Apartment-With-AC.h112677301.Hotel-Information)

$88 nightly

$88 total

Mar 13 - Mar 14

[](https://www.expedia.com/Puerto-Ayora-Hotels-2-Bedroom-Apartment-With-AC.h112677301.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/aa67740e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/77881106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/2ebaba6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/f2ba9c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-FAMILY-SUITE-In-Puerto-Ayora.h82555432.Hotel-Information)

10/10

Exceptional

(1 review)

"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nathan M.

$227 nightly

$227 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-FAMILY-SUITE-In-Puerto-Ayora.h82555432.Hotel-Information)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/406de75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/cb5f3162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/baa439a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/6408dac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-TWO-Bedrooms-Apartment-ON-THE-First-Floor-IN-Arianas-Galapagos-Hostal.h103058515.Hotel-Information)

$89 nightly

$99 total

Mar 11 - Mar 12

[](https://www.expedia.com/Puerto-Ayora-Hotels-TWO-Bedrooms-Apartment-ON-THE-First-Floor-IN-Arianas-Galapagos-Hostal.h103058515.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/937eb7c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/ff40a829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, books](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/3ba85021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/89f46e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Puerto Ayora, Santa Cruz Island

[](https://www.expedia.com/Puerto-Ayora-Hotels-Island-Life-Duplex-Great-For-Groups.h121711100.Hotel-Information)

$314 nightly

$356 total

Mar 20 - Mar 21

[](https://www.expedia.com/Puerto-Ayora-Hotels-Island-Life-Duplex-Great-For-Groups.h121711100.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25&regionId=6336630&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## 

The Annual Vacation Sale

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=CABIN)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=APART_HOTEL)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=VACATION_HOME)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=CONDO)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santa+Fe+Island%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=6336630&latLong=-0.81832%2C-90.054753&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=APARTMENT)

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## Top Santa Fe Island Hotel Reviews

![Hotel Cucuve](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/0a441130_y.jpg)

### Hotel Cucuve

10/10 Excellent

"Very happy with the value provided. Location is right in the middle of town. Ana was very helpful and informative. "

[](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information)

![Maidith Galapagos Inn](https://images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/96c0ae07_y.jpg)

### Maidith Galapagos Inn

10/10 Excellent

"The hotel is just like the pictures. It’s close to the Darwin Center and we were able to walk everywhere. The owners could not do enough for us and SO kind and friendly. The breakfast was unbelievable. There was fresh fruit everyday with yogurt and granola, juice, unlimited coffee and something homemade each morning. One day we had the best empanadas we had ever had! We would stay at this hotel again in a heartbeat! Thanks guys for making our stay so enjoyable:)"

[](https://expedia.com/Puerto-Ayora-Hotels-Maidith-Galapagos-Inn.h88474681.Hotel-Information)

![Hotel Ninfa](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/bf30a401_y.jpg)

### Hotel Ninfa

8/10 Good

"Rooms are OK staff were very nice and helpful. Breakfast was good who was nice. Hotel is close to town. "

[](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information)

![Blu Galapagos Sustainable Waterfront Lodge](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/92acdc7e_y.jpg)

### Blu Galapagos Sustainable Waterfront Lodge

10/10 Excellent

"Great spaces "

[](https://expedia.com/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information)

![Posada del Mar](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/e7fb3ff1_y.jpg)

### Posada del Mar

10/10 Excellent

"Great Staff!"

[](https://expedia.com/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information)

![El Barranco Galapagos](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/9ff6c70e_y.jpg)

### El Barranco Galapagos

10/10 Excellent

"Beautiful room, pristine location, staff is professional and at your service."

[](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Barranco-Galapagos.h111508035.Hotel-Information)

![Ikala Galapagos Hotel](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/f2307f3e_y.jpg)

### Ikala Galapagos Hotel

10/10 Excellent

"Amazing hotel, clean and beautiful. Special thanks for the attentive young man on reception. The hotel is close to everything, beautiful room and bathroom. Nice view of the pool. I enjoyed my drink on the rooftop at night as well. "

[](https://expedia.com/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information)

![Hotel el descanso del Guia](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/48310af4_y.jpg)

### Hotel el descanso del Guia

8/10 Good

"The staff was amazing, so attentive and kind!"

[](https://expedia.com/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information)

![Capitan Max B&B](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/2ca19af6_y.jpg)

### Capitan Max B&B

10/10 Excellent

"My husband and I LOVED our stay! The owners are incredibly friendly and helpful- they were able to answer questions about transportation, dining recommendations, and more. There was a delicious homemade breakfast every morning. The rooms are spacious and very clean. They even helped us book our inter island ferries. The location is also perfect- quiet street but right next to everything you need in Puerto Ayora. If you’re staying on Santa Cruz, you will not regret booking here!"

[](https://expedia.com/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information)

## Find out more about Santa Fe Island

**Everything you need to know about Santa Fe Island vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Fe Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Fe Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santa Fe Island vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santa Fe Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Fe Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $76 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santa Fe Island rentals**

At Expedia, we put the best Santa Fe Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Fe Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Fe Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Fe Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Santa Fe Island

### Trending destinations on Expedia.com

- [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals)
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- [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals)
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- [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals)
- [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals)
- [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)
- [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals)
- [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals)
- [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals)
- [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals)
- [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals)
- [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals)
- [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)
- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Apartments in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Apartments.d6336630-aaApartments.Travel-Guide-Accommodation)
- [Vacation Homes in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Private-Vacation-Homes.d6336630-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [B&B in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Bed-And-Breakfast.d6336630-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Aparthotels in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Apart-Hotels.d6336630-aaApartHotels.Travel-Guide-Accommodation)
- [Guest Houses in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Guest-Houses.d6336630-aaGuestHouses.Travel-Guide-Accommodation)
- [Cottages in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Cottages.d6336630-aaCottages.Travel-Guide-Accommodation)
- [Hostels in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Hostels.d6336630-aaHostels.Travel-Guide-Accommodation)
- [Villas in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Villas.d6336630-aaVillas.Travel-Guide-Accommodation)
- [Lodges in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Lodges.d6336630-aaLodges.Travel-Guide-Accommodation)
- [Resorts in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Resorts.d6336630-aaResorts.Travel-Guide-Accommodation)
- [Condo Rentals in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Condos.d6336630-aaCondos.Travel-Guide-Accommodation)
- [Cabin Rentals in Santa Fe Island ](https://expedia.com/Santa-Fe-Island-Cabins.d6336630-aaCabins.Travel-Guide-Accommodation)

### Expedia's Latest Trends

Hotels

- [Hotels in Floreana Island](https://expedia.com/Floreana-Island-Hotels.d6336634.Travel-Guide-Hotels)
- [Hotels in Rabida Island](https://expedia.com/Rabida-Island-Hotels.d6336653.Travel-Guide-Hotels)
- [San Cristobal Island Oceanfront Hotels](https://expedia.com/San-Cristobal-Island-Hotels-Oceanfront-Hotels.0-0-d6138895-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
- [Hotels in San Cristobal Island](https://expedia.com/San-Cristobal-Island-Hotels.d6138895.Travel-Guide-Hotels)
- [Isabela Island Cheap Hotels](https://expedia.com/Isabela-Island-Hotels-Cheap-Hotels.0-0-d6085329-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Santa Cruz Island Family Hotels](https://expedia.com/Santa-Cruz-Island-Hotels-Family-Hotel.0-0-d6053670-tFamilyHotel.Travel-Guide-Filter-Hotels)
- [Isabela Island Family Hotels](https://expedia.com/Isabela-Island-Hotels-Family-Hotel.0-0-d6085329-tFamilyHotel.Travel-Guide-Filter-Hotels)
- [Hotels in Isabela Island](https://expedia.com/Isabela-Island-Hotels.d6085329.Travel-Guide-Hotels)
- [Hotels in Espanola Island](https://expedia.com/Espanola-Island-Hotels.d6336647.Travel-Guide-Hotels)
- [Floreana Island Hotels with Restaurants](https://expedia.com/Floreana-Island-Hotels-Hotels-With-Restaurants.0-0-d6336634-tHotelswithRestaurants.Travel-Guide-Filter-Hotels)
- [San Cristobal Island Hotels with a Pool](https://expedia.com/San-Cristobal-Island-Hotels-Hotel-With-Pool.0-0-d6138895-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Santa Cruz Island 3 Star Hotels](https://expedia.com/3Star-Santa-Cruz-Island-Hotels.s30-0-d6053670.Travel-Guide-Filter-Hotels)
- [Hotels in Santa Cruz Island](https://expedia.com/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)
- [Santiago Island 4 Star Hotels](https://expedia.com/4Star-Santiago-Island-Hotels.s40-0-d6336381.Travel-Guide-Filter-Hotels)

Flights

- [Flights to Santa Cruz Island](https://expedia.com/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)
- [Flights to Isabela Island](https://expedia.com/Cheap-Flights-To-Isabela-Island.d6085329.Travel-Guide-Flights)

Cars

- [Car rentals in Floreana Island](https://expedia.com/Car-Rentals-In-Floreana-Island.d6336634.Car-Rental-Guide)
- [Car rentals in San Cristobal Island](https://expedia.com/Car-Rentals-In-San-Cristobal-Island.d6138895.Car-Rental-Guide)

Activities

- [Things to do in Isabela Island](https://expedia.com/Things-To-Do-In-Isabela-Island.d6085329.Travel-Guide-Activities)
- [Things to do in Santa Cruz Island](https://expedia.com/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)

Packages

- [Floreana Island Vacation](https://expedia.com/Floreana-Island.d6336634.Destination-Travel-Guides)
- [Bartolome Island Vacation](https://expedia.com/Bartolome-Island.d6336382.Destination-Travel-Guides)
- [Santiago Island Vacation](https://expedia.com/Santiago-Island.d6336381.Destination-Travel-Guides)
- [Isabela Island Vacation](https://expedia.com/Isabela-Island.d6085329.Destination-Travel-Guides)

General

- [Visit Espanola Island](https://expedia.com/Espanola-Island.dx6336647)
- [Visit San Cristobal Island](https://expedia.com/San-Cristobal-Island.dx6138895)
- [Visit Santiago Island](https://expedia.com/Santiago-Island.dx6336381)
- [Visit Bartolome Island](https://expedia.com/Bartolome-Island.dx6336382)
- [Visit Floreana Island](https://expedia.com/Floreana-Island.dx6336634)
- [Visit Santa Cruz Island](https://expedia.com/Santa-Cruz-Island.dx6053670)