Title: La Serena Vacation Packages 2026 | Expedia.com [La Serena Travel Guide](https://expedia.com/La-Serena.dx2139)[Hotels in La Serena](https://expedia.com/La-Serena-Hotels.d2139.Travel-Guide-Hotels)[Vacation Rentals in La Serena](https://expedia.com/La-Serena-Vacation-Rentals.d2139.Travel-Guide-VacationRentals)[Flights to La Serena](https://expedia.com/Cheap-Flights-To-La-Serena.d2139.Travel-Guide-Flights)[Things to do in La Serena](https://expedia.com/Things-To-Do-In-La-Serena.d2139.Travel-Guide-Activities)[Car Rentals in La Serena](https://expedia.com/Car-Rentals-In-La-Serena.d2139.Car-Rental-Guide) ![](https://images.trvl-media.com/place/2139/69281035-28af-4d6a-8fc4-dbf1d73d5504.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # La Serena Vacations ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your La Serena Vacation Book a La Serena vacation package and prepare for an awesome adventure. Known for its beaches and coastal scenery, there's tons to like about this fascinating city. Like to explore your surroundings? [Kokoro No Niwa Japanese Garden](https://www.expedia.com/Kokoro-No-Niwa-Japanese-Garden-La-Serena.d6098428.Vacation-Attraction), [La Serena Beach](https://www.expedia.com/La-Serena-Beach-La-Serena.d6098436.Vacation-Attraction) and [Playa La Herradura](https://www.expedia.com/Playa-La-Herradura-Coquimbo.d553248621532463476.Vacation-Attraction) are just three of the best places to visit during a trip to La Serena. Whoever you're heading away with and whatever your budget, your ultimate La Serena vacation is just clicks away with Expedia. ### Discover the most popular places to visit in La Serena #### Sea Avenue 4.5/5(4 reviews) Learn about the local history of La Serena with a stop at Sea Avenue. While you're in the area, stroll along the beaches. [](https://expedia.com/Sea-Avenue-La-Serena.d6311984.Vacation-Attraction) #### Mall Plaza La Serena 4.5/5(4 reviews) You can search for that perfect souvenir at Mall Plaza La Serena during your trip to La Serena. While you're in the area, stroll along the beaches. [](https://expedia.com/Mall-Plaza-La-Serena-La-Serena.d6311978.Vacation-Attraction) #### La Serena Lighthouse 4/5(3 reviews) Learn about the local history of La Serena with a stop at La Serena Lighthouse. While you're in the area, stroll along the beaches. [](https://expedia.com/La-Serena-Lighthouse-La-Serena.d6098434.Vacation-Attraction) ### What to do in La Serena ![Elqui Valley Tour: Full Day History and Flavors ](https://mediaim.expedia.com/localexpert/47053317/dd0c7540-eb21-41b0-8130-282ff337b212.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Elqui Valley Tour: History and Flavors (NOT FOR CRUISES) $53 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/elqui-valley-tour-history-and-flavors-not-for-cruises.a47053317.activity-details) ![Must-sees of the Elqui Valley](https://mediaim.expedia.com/localexpert/47761294/7f570aca-ee7c-4700-bd4e-e25b98089138.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Must-sees of the Elqui Valley. Private tour $79 per adult [](https://expedia.com/things-to-do/must-sees-of-the-elqui-valley-private-tour.a47761294.activity-details) ![Elqui valley](https://mediaim.expedia.com/localexpert/1041709/500fef87-4f73-4ea2-977d-ad1f89f5eac0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### La Serena: Full day Tour to Elqui Valley $320 per adult [](https://expedia.com/things-to-do/la-serena-full-day-tour-to-elqui-valley.a1041709.activity-details) [See all activities in La Serena](https://expedia.com/things-to-do/search?rid=2139) ## La Serena Hotel Deals ![Hotel Diego de Almagro La Serena Express](https://images.trvl-media.com/lodging/111000000/110440000/110439900/110439848/5ac899a7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Diego de Almagro La Serena Express 0235 Avenida Francisco de Aguirre La Serena Fully refundableReserve now, pay when you stay $95 nightly $95 total Mar 20 - Mar 21 8.6/10 Excellent! (55 reviews) Room quality was very good and the room was very clean every day, Reviewed on Jan 25, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&selected=110439848&PinnedHotelID=110439848&HadPinnedHotel=true®ionId=2139) ![Hotel Diego de Almagro La Serena](https://images.trvl-media.com/lodging/16000000/15580000/15570400/15570373/332a6c16_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Diego de Almagro La Serena Avenida Francisco de Aguirre 0665 La Serena Coquimbo Fully refundableReserve now, pay when you stay $120 nightly $120 total Mar 20 - Mar 21 8.6/10 Excellent! (346 reviews) Efficient front-desk staff, a comfortable quiet room on the 3rd floor,and an excellent breakfast Reviewed on Feb 13, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&selected=15570373&PinnedHotelID=15570373&HadPinnedHotel=true®ionId=2139) ![Hotel y Cabañas Campanario](https://images.trvl-media.com/lodging/3000000/2140000/2133800/2133775/974addd9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel y Cabañas Campanario Avenida del Mar 4600 La Serena Fully refundableReserve now, pay when you stay $72 nightly $72 total Mar 29 - Mar 30 [](https://expedia.com/Hotel-Search?startDate=3%2F29%2F2026&endDate=3%2F30%2F2026&selected=2133775&PinnedHotelID=2133775&HadPinnedHotel=true®ionId=2139) [See all 479 properties in La Serena](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=2139) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best La Serena Vacation Packages ### La Serena Beach Vacation There's nothing more delightful than a La Serena vacation. Whether you're treating yourself to delicious cocktails at a local bar or reading your favorite novel by the water's edge, your trip to La Serena is the time to live out your beachy dreams. Many visitors will tell you to stay near La Serena Beach, located just 2 miles (4 km) from the center of town. However, you'll also find a fantastic range of La Serena packages close to Totoralillo Beach and Canto del Agua Beach, two other well-loved nearby options. ### Things You Should Know About La Serena - Staying close to the water means picture-perfect vistas and long walks along the shoreline just before nightfall. Cast your eye over our [La Serena beach hotels](https://www.expedia.com/La-Serena-Hotels-Beach-Hotel.0-0-d2139-tBeachHotel.Travel-Guide-Filter-Hotels?lang=en&rfrr=ATG.LP.BodyContent) and see what you can find. - Apartments are also popular with many visitors to the area. [Depto. Av. Del Mar Aqua Serena](https://www.expedia.com/La-Serena-Hotels-Depto-Av-Del-Mar-Aqua-Serena.h21940613.Hotel-Information) and [Vacaciones en Laguna del Mar](https://www.expedia.com/La-Serena-Hotels-Vacaciones-En-Laguna-Del-Mar.h21913557.Hotel-Information) are examples of what you can expect from this type of accommodation. - Alternatively, let one of our [All-Inclusive hotels in La Serena](https://www.expedia.com/La-Serena-Hotels-Beach-Hotel.0-0-d2139-tAllinclusiveHotel.Travel-Guide-Filter-Hotels?lang=en&rfrr=ATG.LP.BodyContent) take care of all the finer details. That means more time for you to get on with the pressing task of relaxing and unwinding. - La Serena, population 154,500, is a popular vacation destination for so many reasons. Discover some handy tips on our [La Serena things to do page](https://www.expedia.com/things-to-do/en/search?rid=2139&rfrr=ATG.LP.BodyContent). - Kokoro No Niwa Japanese Garden is one big sight you need to see here. For plenty of other popular travel plan ideas, browse our La Serena vacation deals. ## La Serena Essential Information | Language | Spanish | | --------------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Chilean pesos | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | La Florida Airport (LSC) | | Population | 154,500 | | Max Temp Winter | 65ºF | | Max Temp Summer | 70ºF | | Top Sights | [La Serena Beach](https://www.expedia.com/La-Serena-Beach-La-Serena.d6098436.Vacation-Attraction), [Playa La Herradura](https://www.expedia.com/Playa-La-Herradura-Coquimbo.d553248621532463476.Vacation-Attraction) and [Cuatro Esquinas Beach](https://www.expedia.com/Cuatro-Esquinas-Beach-La-Serena.d6311993.Vacation-Attraction) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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[](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ Friendly Vacations [](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adventure Vacations [](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click) ![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does a La Serena vacation package cost? ### What are the cheapest months to go to La Serena? ### How many days is enough for La Serena? ### Is it worth booking a vacation package to La Serena? ### How to find the best La Serena package deals? ### Is it cheaper to book a La Serena vacation as a package? ### When to book a vacation package to La Serena? ### How to plan a trip to La Serena? > 1. Choose when to travel: Check your schedule and pack your bags. Your favorite season and the activities on offer will also help you decide when to vacation in La Serena. > 2. Figure out your budget: Ensure you have enough money to pay for everything from transportation and dining out to airfares and activities. Your accommodations will likely be the biggest expense during your trip to La Serena. > 3. Discover La Serena using our [trip planning tool](https://www.expedia.com/why/trip-planning): Gain insights into the top attractions and best stays for your trip to La Serena. You can also save your favorite places, collaborate with your group and organize all your plans in one place. > 4. Decide how long to go for: Now that you're up to speed on La Serena, you can work out the right length of your break. Create a rough itinerary and give yourself enough time to cover everything you want to do. > 5. Bundle your bookings: With your travel dates in order, you can combine your flights, hotels, car rental and more into a tailored La Serena vacation package. > 6. Book any excursions or activities: Now to the fun part — locking in everything you want to do and see. Browse some of the best [things to do in La Serena](https://www.expedia.com/Things-To-Do-In-La-Serena.d2139.Travel-Guide-Activities) and reserve your tickets early to save time (and maybe some cash too!). ### Does Expedia offer Book Now, Pay Later La Serena vacation packages? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Casino Hotels in Coquimbo Region ](https://www.expedia.com/Destinations-In-Coquimbo-Region-Casino-Hotel.0-0-d6236544-tCasinoHotel.Hotel-Filter-Destinations) - [Coquimbo Region Hotels ](https://www.expedia.com/Destinations-In-Coquimbo-Region.d6236544.Hotel-Destinations) - [Gay friendly Hotels in Coquimbo Region ](https://www.expedia.com/Destinations-In-Coquimbo-Region-LGBT-Welcoming-Hotel.0-0-d6236544-tLGBTWelcomingHotel.Hotel-Filter-Destinations) - [Cabin Rentals in Coquimbo Region ](https://www.expedia.com/Coquimbo-Region-Cabins.d6236544-aaCabins.Travel-Guide-Accommodation) - [Hostels in Coquimbo Region ](https://www.expedia.com/Coquimbo-Region-Hostels.d6236544-aaHostels.Travel-Guide-Accommodation) - [Hotels with Free Breakfast in Coquimbo Region ](https://www.expedia.com/Destinations-In-Coquimbo-Region-Hotels-With-Complimentary-Breakfast.0-0-d6236544-tHotelswithComplimentaryBreakfast.Hotel-Filter-Destinations) - [Resorts & Hotels with Spas in Coquimbo Region ](https://www.expedia.com/Destinations-In-Coquimbo-Region-Spa-Hotel.0-0-d6236544-tSpaHotel.Hotel-Filter-Destinations) - [Pet-Friendly Hotels in Coquimbo Region ](https://www.expedia.com/Destinations-In-Coquimbo-Region-Pet-Friendly-Hotel.0-0-d6236544-tPetfriendlyHotel.Hotel-Filter-Destinations) - [Hotels near Casa Gabriel Gonzalez Videla Historical Museum ](https://www.expedia.com/Casa-Gabriel-Gonzalez-Videla-Historical-Museum-Hotels.0-l6293367-0.Travel-Guide-Filter-Hotels) - [Hotels near Kokoro No Niwa Japanese Garden ](https://www.expedia.com/Kokoro-No-Niwa-Japanese-Garden-Hotels.0-l6098428-0.Travel-Guide-Filter-Hotels) - [Hotels near La Recova Market ](https://www.expedia.com/La-Recova-Market-Hotels.0-l6293404-0.Travel-Guide-Filter-Hotels) - [Hotels near Casa Carmona ](https://www.expedia.com/Casa-Carmona-Hotels.0-l6312008-0.Travel-Guide-Filter-Hotels) - [Hotels near Sea Avenue ](https://www.expedia.com/Sea-Avenue-Hotels.0-l6311984-0.Travel-Guide-Filter-Hotels) - [Hotels near Cuatro Esquinas Beach ](https://www.expedia.com/Cuatro-Esquinas-Beach-Hotels.0-l6311993-0.Travel-Guide-Filter-Hotels) - [Hotels near Elqui Valley ](https://www.expedia.com/Elqui-Valley-Hotels.0-l6293291-0.Travel-Guide-Filter-Hotels) - [Hotels near Coquimbo Casino ](https://www.expedia.com/Coquimbo-Casino-Hotels.0-l553248621532463477-0.Travel-Guide-Filter-Hotels) - [Hotels near Playa La Herradura ](https://www.expedia.com/Playa-La-Herradura-Hotels.0-l553248621532463476-0.Travel-Guide-Filter-Hotels) - [Flights from Santiago (SCL) to La Serena (LSC) ](https://www.expedia.com/lp/flights/scl/lsc/santiago-to-la-serena) - [Flights from Chicago (ORD) to La Serena (LSC) ](https://www.expedia.com/lp/flights/ord/lsc/chicago-to-la-serena) - [Flights from Miami (MIA) to La Serena (LSC) ](https://www.expedia.com/lp/flights/mia/lsc/miami-to-la-serena) - [Flights from Atlanta (ATL) to La Serena (LSC) ](https://www.expedia.com/lp/flights/atl/lsc/atlanta-to-la-serena) - [Flights from Los Angeles (LAX) to La Serena (LSC) ](https://www.expedia.com/lp/flights/lax/lsc/los-angeles-to-la-serena) - [Flights from La Florida ](https://www.expedia.com/lp/airports/lsc/flights-from-la-florida-airport) - [Flights from Lima (LIM) to La Serena (LSC) ](https://www.expedia.com/lp/flights/lim/lsc/lima-to-la-serena) - [Flights from Buenos Aires (EZE) to La Serena (LSC) ](https://www.expedia.com/lp/flights/eze/lsc/buenos-aires-to-la-serena) - [Flights from Calama (CJC) to La Serena (LSC) ](https://www.expedia.com/lp/flights/cjc/lsc/calama-to-la-serena) - [Flights from San Jose (SJC) to La Serena (LSC) ](https://www.expedia.com/lp/flights/sjc/lsc/san-jose-to-la-serena) - [Flights from Antofagasta (ANF) to La Serena (LSC) ](https://www.expedia.com/lp/flights/anf/lsc/antofagasta-to-la-serena) - [Flights from New York (JFK) to La Serena (LSC) ](https://www.expedia.com/lp/flights/jfk/lsc/new-york-to-la-serena) - [Flights from Copiapo (CPO) to La Serena (LSC) ](https://www.expedia.com/lp/flights/cpo/lsc/copiapo-to-la-serena) - [Flights from Asuncion (ASU) to La Serena (LSC) ](https://www.expedia.com/lp/flights/asu/lsc/asuncion-to-la-serena) - [Flights from Dallas (DFW) to La Serena (LSC) ](https://www.expedia.com/lp/flights/dfw/lsc/dallas-to-la-serena) - [Flights from Mendoza (MDZ) to La Serena (LSC) ](https://www.expedia.com/lp/flights/mdz/lsc/mendoza-to-la-serena) - [Flights from Washington (IAD) to La Serena (LSC) ](https://www.expedia.com/lp/flights/iad/lsc/washington-to-la-serena) - [Flights from Charlotte (CLT) to La Serena (LSC) ](https://www.expedia.com/lp/flights/clt/lsc/charlotte-to-la-serena) - [Flights from Cusco (CUZ) to La Serena (LSC) ](https://www.expedia.com/lp/flights/cuz/lsc/cusco-to-la-serena) - [Flights from Panama City (PTY) to La Serena (LSC) ](https://www.expedia.com/lp/flights/pty/lsc/panama-city-to-la-serena) - [Flights from Punta Arenas (PUQ) to La Serena (LSC) ](https://www.expedia.com/lp/flights/puq/lsc/punta-arenas-to-la-serena) - [Flights from Denver (DEN) to La Serena (LSC) ](https://www.expedia.com/lp/flights/den/lsc/denver-to-la-serena) - [Flights from Concepcion (CCP) to La Serena (LSC) ](https://www.expedia.com/lp/flights/ccp/lsc/concepcion-to-la-serena) - [Flights from Vina del Mar (KNA) to La Serena (LSC) ](https://www.expedia.com/lp/flights/kna/lsc/vina-del-mar-to-la-serena) - [Flights from Houston (IAH) to La Serena (LSC) ](https://www.expedia.com/lp/flights/iah/lsc/houston-to-la-serena) - [Flights from Nairobi (NBO) to La Serena (LSC) ](https://www.expedia.com/lp/flights/nbo/lsc/nairobi-to-la-serena) - [Flights from Iquique (IQQ) to La Serena (LSC) ](https://www.expedia.com/lp/flights/iqq/lsc/iquique-to-la-serena) - [Flights from Las Vegas (LAS) to La Serena (LSC) ](https://www.expedia.com/lp/flights/las/lsc/las-vegas-to-la-serena) - [Flights from Phoenix (PHX) to La Serena (LSC) ](https://www.expedia.com/lp/flights/phx/lsc/phoenix-to-la-serena) - [Flights from Portland (PDX) to La Serena (LSC) ](https://www.expedia.com/lp/flights/pdx/lsc/portland-to-la-serena) - [Flights from Santo Domingo (SDQ) to La Serena (LSC) ](https://www.expedia.com/lp/flights/sdq/lsc/santo-domingo-to-la-serena) - [Flights from Baltimore (BWI) to La Serena (LSC) ](https://www.expedia.com/lp/flights/bwi/lsc/baltimore-to-la-serena) - [Flights from New York (NYC) to La Serena (LSC) ](https://www.expedia.com/lp/flights/nyc/lsc/new-york-to-la-serena) - [Flights from Seattle (SEA) to La Serena (LSC) ](https://www.expedia.com/lp/flights/sea/lsc/seattle-to-la-serena) - [Flights from San Juan (SJU) to La Serena (LSC) ](https://www.expedia.com/lp/flights/sju/lsc/san-juan-to-la-serena) - [Flights from Quito (UIO) to La Serena (LSC) ](https://www.expedia.com/lp/flights/uio/lsc/quito-to-la-serena) - [Flights from Raleigh (RDU) to La Serena (LSC) ](https://www.expedia.com/lp/flights/rdu/lsc/raleigh-to-la-serena) - [Flights from Detroit (DTW) to La Serena (LSC) ](https://www.expedia.com/lp/flights/dtw/lsc/detroit-to-la-serena) - [Flights from Salt Lake City (SLC) to La Serena (LSC) ](https://www.expedia.com/lp/flights/slc/lsc/salt-lake-city-to-la-serena) - [Flights from Boston (BOS) to La Serena (LSC) ](https://www.expedia.com/lp/flights/bos/lsc/boston-to-la-serena) - [Flights from Fort Lauderdale (FLL) to La Serena (LSC) ](https://www.expedia.com/lp/flights/fll/lsc/fort-lauderdale-to-la-serena) - [Flights from Tampa (TPA) to La Serena (LSC) ](https://www.expedia.com/lp/flights/tpa/lsc/tampa-to-la-serena) - [Flights from Uyuni (UYU) to La Serena (LSC) ](https://www.expedia.com/lp/flights/uyu/lsc/uyuni-to-la-serena) - [Flights from Baton Rouge (BTR) to La Serena (LSC) ](https://www.expedia.com/lp/flights/btr/lsc/baton-rouge-to-la-serena) - [Flights from Cleveland (CLE) to La Serena (LSC) ](https://www.expedia.com/lp/flights/cle/lsc/cleveland-to-la-serena) - [Flights from Philadelphia (PHL) to La Serena (LSC) ](https://www.expedia.com/lp/flights/phl/lsc/philadelphia-to-la-serena) - [Flights from Cincinnati (CVG) to La Serena (LSC) ](https://www.expedia.com/lp/flights/cvg/lsc/cincinnati-to-la-serena) - [Flights from Minneapolis (MSP) to La Serena (LSC) ](https://www.expedia.com/lp/flights/msp/lsc/minneapolis-to-la-serena) - [Flights from Montreal (YUL) to La Serena (LSC) ](https://www.expedia.com/lp/flights/yul/lsc/montreal-to-la-serena) - [Flights from Toronto (YYZ) to La Serena (LSC) ](https://www.expedia.com/lp/flights/yyz/lsc/toronto-to-la-serena) - [Flights from Paris (CDG) to La Serena (LSC) ](https://www.expedia.com/lp/flights/cdg/lsc/paris-to-la-serena) - [Flights from Pisa (PSA) to La Serena (LSC) ](https://www.expedia.com/lp/flights/psa/lsc/pisa-to-la-serena) - [Flights from Seoul (ICN) to La Serena (LSC) ](https://www.expedia.com/lp/flights/icn/lsc/seoul-to-la-serena) - [Flights from Nashville (BNA) to La Serena (LSC) ](https://www.expedia.com/lp/flights/bna/lsc/nashville-to-la-serena) - [Flights from Cartagena (CTG) to La Serena (LSC) ](https://www.expedia.com/lp/flights/ctg/lsc/cartagena-to-la-serena) - [Flights from Cali (CLO) to La Serena (LSC) ](https://www.expedia.com/lp/flights/clo/lsc/cali-to-la-serena) - [Flights from Kota (KTU) to La Serena (LSC) ](https://www.expedia.com/lp/flights/ktu/lsc/kota-to-la-serena) - [Flights from Copenhagen (CPH) to La Serena (LSC) ](https://www.expedia.com/lp/flights/cph/lsc/copenhagen-to-la-serena) - [Flights from Sikeston (SIK) to La Serena (LSC) ](https://www.expedia.com/lp/flights/sik/lsc/sikeston-to-la-serena) - [Flights from Honolulu (HNL) to La Serena (LSC) ](https://www.expedia.com/lp/flights/hnl/lsc/honolulu-to-la-serena) - [Flights from Chicago (MDW) to La Serena (LSC) ](https://www.expedia.com/lp/flights/mdw/lsc/chicago-to-la-serena) - [La Serena Cathedral ](https://www.expedia.com/La-Serena-Cathedral-La-Serena.d6098420.Vacation-Attraction) - [Casa Gabriel Gonzalez Videla Historical Museum ](https://www.expedia.com/Casa-Gabriel-Gonzalez-Videla-Historical-Museum-La-Serena.d6293367.Vacation-Attraction) - [Casa Pinera ](https://www.expedia.com/Casa-Pinera-La-Serena.d553248621532463489.Vacation-Attraction) - [Santo Domingo Church ](https://www.expedia.com/Santo-Domingo-Church-La-Serena.d6098422.Vacation-Attraction) - [Visit Coquimbo Region ](https://www.expedia.com/Coquimbo-Region.dx6236544) - [Kokoro No Niwa Japanese Garden ](https://www.expedia.com/Kokoro-No-Niwa-Japanese-Garden-La-Serena.d6098428.Vacation-Attraction) - [Parque Japones Kokoro No Niwa ](https://www.expedia.com/Parque-Japones-Kokoro-No-Niwa-La-Serena.d553248621532374494.Vacation-Attraction) - [La Serena Archaeological Museum ](https://www.expedia.com/La-Serena-Archaeological-Museum-La-Serena.d6098424.Vacation-Attraction) - [La Recova Market ](https://www.expedia.com/La-Recova-Market-La-Serena.d6293404.Vacation-Attraction) - [Observatorio Turístico Collowara ](https://www.expedia.com/Observatorio-Turistico-Collowara-La-Serena.d553248621532374491.Vacation-Attraction) - [Giliberto House ](https://www.expedia.com/Giliberto-House-La-Serena.d553248621563217376.Vacation-Attraction) - [Casa Carmona ](https://www.expedia.com/Casa-Carmona-La-Serena.d6312008.Vacation-Attraction) - [La Portada Stadium ](https://www.expedia.com/La-Portada-Stadium-La-Serena.d6098416.Vacation-Attraction) - [Casa de La Providencia Chapel and Convent ](https://www.expedia.com/Casa-De-La-Providencia-Chapel-And-Convent-La-Serena.d6293451.Vacation-Attraction) - [La Serena Lighthouse ](https://www.expedia.com/La-Serena-Lighthouse-La-Serena.d6098434.Vacation-Attraction) - [Sea Avenue ](https://www.expedia.com/Sea-Avenue-La-Serena.d6311984.Vacation-Attraction) - [Elqui Valley ](https://www.expedia.com/Elqui-Valley-Coquimbo-Region.d6293291.Vacation-Attraction) - [Car rentals near Coquimbo Region ](https://www.expedia.com/Destinations-In-Coquimbo-Region.d6236544.Car-Rental-Destinations) - [Car rentals near El Faro Beach ](https://www.expedia.com/Car-Rentals-In-El-Faro-Beach.d6311986.Car-Rental-Guide) - [Car rental La Serena Airport (LSC) ](https://www.expedia.com/Car-Rentals-In-La-Florida.d6029785.Car-Rental-Guide) - [Car rentals near Elqui Valley ](https://www.expedia.com/Car-Rentals-In-Elqui-Valley.d6293291.Car-Rental-Guide) - [Things to do in Coquimbo Region ](https://www.expedia.com/Things-To-Do-In-Coquimbo-Region.d6236544.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. 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