Visit Otay Mesa West
Popular places to visit
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
San Diego Convention Center
Whether you come for Comic-Con or a medical convention, this huge gathering place in the Marina District of San Diego will more than satisfy your needs.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Mission Beach
A favorite vacation spot for 100 years, this seaside village combines old-fashioned charm with modern amenities.
SeaWorld
Visit one of the world’s largest marine parks for talented and amazing and animals, electrifying rides, conservation education and seasonal events.
Things to do
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
San Diego Sunset Cruise from Mission Bay
Coronado: San Diego Bay Jetski Rental
San Diego: Whale Watching Cruise
Otay Mesa West Hotel Deals
Handlery Hotel
Reviewed on Jul 26, 2025
Wyndham San Diego Bayside
Reviewed on Jul 25, 2025
Manchester Grand Hyatt San Diego
Reviewed on Jul 28, 2025
The Dana on Mission Bay
Reviewed on Jul 25, 2025
Marriott Marquis San Diego Marina
Reviewed on Jul 26, 2025
The Dextro Hotel, BW Premier Collection
Reviewed on Jul 25, 2025
Other neighborhoods around Otay Mesa West
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Mid-City
If you're spending time in Mid-City, check out sights like Cal Coast Credit Union Open Air Theater or Viejas Arena and hop on the metro to see more the city at SDSU Transit Center Station or Alvarado Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
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