Otay Mesa West, CA

San Diego

Photo by Leonardo De Leon
Photo by Leonardo De Leon

Popular places to visit

Things to do


Otay Mesa West Hotel Deals

Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$123 nightly
The price is $141 total per night from Dec 8 to Dec 9
$141 total
Dec 8 - Dec 9
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9/10 Wonderful! (3,159 reviews)
Hot tub! Room #253 is perfect.

Reviewed on Dec 4, 2025

Bay Club Hotel & Marina
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
$152 nightly
The price is $175 total per night from Dec 7 to Dec 8
$175 total
Dec 7 - Dec 8
Total with taxes and fees
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (2,983 reviews)
Friendly, staff was very helpful, great size rooms, and over all was an amazing stay

Reviewed on Dec 1, 2025

Legacy Resort Hotel & Spa
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
$210 nightly
The price is $243 total per night from Jan 1 to Jan 2
$243 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
8.8/10 Excellent! (3,128 reviews)
The room was so clean and the view amazing will definitely come back

Reviewed on Nov 30, 2025

Hard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
$103 nightly
The price is $120 total per night from Dec 15 to Dec 16
$120 total
Dec 15 - Dec 16
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (712 reviews)
Clean room, nice staff

Reviewed on Dec 5, 2025

The DEXTRO Little Italy, BW Premier Collection
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South San Diego CA
$98 nightly
The price is $113 total per night from Jan 4 to Jan 5
$113 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,274 reviews)
Spacious and clean rooms, helpful staff

Reviewed on Dec 2, 2025

Hampton Inn San Diego/Mission Valley
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St San Diego CA
$119 nightly
The price is $137 total per night from Jan 4 to Jan 5
$137 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Port of ...
9/10 Wonderful! (375 reviews)
Very clean!

Reviewed on Dec 2, 2025

Hampton Inn & Suites by Hilton San Diego SeaWorld
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Otay Mesa West

Petco Park featuring a statue or sculpture

East Village

Travelers choose East Village for its lively bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.

East Village
Gaslamp Quarter showing signage, night scenes and street scenes

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Gaslamp Quarter
US Grant Hotel

Downtown San Diego

4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Downtown San Diego
Marina District featuring a bay or harbor

Marina District

Known for its fantastic nightlife and captivating waterfront views, there's plenty to explore in Marina District. Check out top attractions like Seaport Village and The Rady Shell at Jacobs Park, and jump on the metro at Seaport Village Station or Convention Center Station to see more of the city.

Marina District
Little Italy

Little Italy

Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.

Little Italy
Try the tamale eggs Benedict!

North Park

4/5(78 area reviews)

North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.

North Park


Otay Mesa West, CA

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