Santa Cruz Vacations from $373

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Your Santa Cruz Vacation

There's no better way to get away than with one of our vacation packages to Santa Cruz. The lively atmosphere and beaches are two of the countless reasons to spend some time in this awesome city. A trip to Santa Cruz is an ideal opportunity to do some sightseeing. Be sure to stop by renowned attractions like Lapostolle Clos Apalta Winery, Laura Hartwig Winery and Casino Colchagua. Your perfect Santa Cruz vacation is a couple of clicks away. Browse airfares, hotels and more on Expedia for an adventure that's tailored just for you.

The Latest Santa Cruz vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Capital Bellet

Hotel Capital Bellet

Providencia
$373
per person
Dec 24 - Dec 28
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Santiago (SCL)
9.2/10 Wonderful! (1,006 reviews)
Room was very small overall was a great place to stay

Reviewed on Oct 9, 2026

Hotel Las Majadas

Hotel Las Majadas

Save 100% on your flight
$529
per person
Dec 24 - Dec 27
found 23 hours ago
Roundtrip flight included
Buenos Aires (BUE) to Santiago (SCL)
9.8/10 Exceptional! (117 reviews)
Although the assigned room was below our expectations, the staff relocated us to a larger and very comfortable small suite. Appreciate the efforts from Esperanza and Felipe to make the rest of our visit to Las Majadas a wonderful and unique experience.

Reviewed on Oct 16, 2026

Aubrey Hotel Boutique

Aubrey Hotel Boutique

Bellavista
Save 100% on your flight
$478
per person
Dec 24 - Dec 28
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Santiago (SCL)
9.4/10 Exceptional! (153 reviews)
Staff was really helpful especially Braulio if you have any questions he will answer them

Reviewed on Oct 16, 2026

Hotel Nodo - El primer hotel de negocios en Chile

Hotel Nodo - El primer hotel de negocios en Chile

Providencia
$427
per person
Dec 24 - Dec 28
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Santiago (SCL)
8.6/10 Excellent! (128 reviews)
Casa Bueras Boutique Hotel

Casa Bueras Boutique Hotel

Downtown Santiago
$533
per person
Dec 24 - Dec 28
found 1 day ago
Roundtrip flight included
Buenos Aires (AEP) to Santiago (SCL)
9.2/10 Wonderful! (561 reviews)
Elegant boutique hotel.

Reviewed on Oct 14, 2026

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Stay near popular Santa Cruz attractions

Lapostolle Clos Apalta Winery

9.4/10 (21 reviews)
Carved into the hillside, Clos Apalta Winery produces award-winning Bordeaux-style wines using a gravitational system. Reserve a private tour to taste premium vintages overlooking the stunning Colchagua Valley.
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Casino Colchagua

8.0/10 (6 reviews)
Chile's first thematic casino blends gaming with colonial-inspired decor that celebrates local heritage. Enjoy slot machines and table games while savoring Chilean cuisine from the adjacent Hotel Santa Cruz Plaza.
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Laura Hartwig Winery

9.0/10 (17 reviews)
This family-run winery in Chile's Colchagua Valley specializes in premium Bordeaux-style wines. Stroll through picturesque vineyards before enjoying intimate tastings paired with local cheeses in their barrel room.
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Colchagua Campo y Vino

9.4/10 (3 reviews)
Immerse yourself in Chile's wine country at this boutique hotel surrounded by Colchagua Valley vineyards. Enjoy personalized service while exploring nearby wineries during harvest festivals or spring blooms.
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Bodega Viña Viu Manent

10.0/10 (1 review)
This historic Chilean winery stands out for its exceptional Malbec wines, a rarity in the region. Take a horse-drawn carriage through sun-dappled vineyards before sampling their acclaimed vintages.
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Museo de Colchagua

9.6/10 (24 reviews)
This renowned private museum houses one of Latin America's most extensive historical collections from prehistoric to modern Chile. Explore pavilions featuring indigenous artifacts and colonial treasures.
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Plaza de Armas

8.2/10 (34 reviews)
This elegant city square features symmetrical walkways and lush gardens at the heart of Santa Cruz. Relax beneath towering trees or catch local cultural events that showcase the region's vibrant community life.
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What to do in Santa Cruz

Make Your Own Wine & Guided Vineyard Tour

Make Your Own Wine & Guided Vineyard Tour

$46
per adult
Make Your Own Wine & Guided Vineyard Tour
Private VIK winery tour + tasting from Santiago

Private VIK winery tour + tasting from Santiago

$365
per adult
Private VIK winery tour + tasting from Santiago
Private Wine Tour Colchagua Valley

Private Wine Journey Through Colchagua Valley

$450
per adult
Private Wine Journey Through Colchagua Valley
See all activities in Santa Cruz

Santa Cruz Hotel Deals

Santa Cruz Plaza

Santa Cruz Plaza

Plaza De Armas 286 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$119 nightly
$119 total
Nov 8 - Nov 9
8.8/10 Excellent! (374 reviews)
"El hotel ya está muy viejo, tiene buenas instalaciones y el spa está bien pero las habitaciones ocupan renovación, sobre todo alfombras y aire acondicionado."

Reviewed on Sep 26, 2026

Santa Cruz Plaza
Hotel Cava Colchagua

Hotel Cava Colchagua

Barreales´s Way Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$143 nightly
$143 total
Oct 20 - Oct 21
9/10 Wonderful! (177 reviews)
"Excelente y original experiencia boutique Una propuesta realmente innovadora. Se trata de un hotel boutique hermoso cuyas habitaciones están acondicionadas dentro de barricas de roble, muy bien adaptadas y acogedoras. Como sugerencia de mejora, creo que a las habitaciones más grandes les vendría ..."

Reviewed on Aug 7, 2026

Hotel Cava Colchagua
Hotel Boutique Vendimia Premium

Hotel Boutique Vendimia Premium

Ismael Valdes 92 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$62 nightly
$62 total
Oct 18 - Oct 19
Hotel Boutique Vendimia Premium
See all 61 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Cruz Vacation Packages

Things to do in Santa Cruz

Santa Cruz, located in the O'Higgins Region of Chile, is perfect for romantic getaways and outdoor adventures. Visitors can enjoy hiking trails, skiing, and wine tastings in the area. Day trips and beach vacations are also popular activities, making Santa Cruz an ideal destination for those seeking entertainment and natural beauty. Explore the stunning landscapes and indulge in local wines for a memorable experience.

Shopping

In Santa Cruz, you can explore local markets like the Santa Cruz Craft Fair for unique souvenirs. If you're up for a drive, visit the Plaza de Armas in nearby towns for more shopping options and local artisan crafts that reflect the region's culture.

Recreation

Experience the tranquility of Viña la Playa, featuring rejuvenating spa treatments and yoga sessions amidst beautiful vineyards. For outdoor enthusiasts, explore the scenic hiking trails of the Colchagua Valley, where you can enjoy nature and stunning landscapes while unwinding in the serene atmosphere of Santa Cruz.

Adventure

Explore the breathtaking landscapes of the Colchagua Valley through exhilarating mountain biking tours. Experience wine tasting at renowned vineyards, where you can savor local flavors. For a thrill, try horseback riding through picturesque trails that showcase the region's natural beauty and rich culture.

Nightlife

Santa Cruz offers a vibrant nightlife with lively bars and cozy venues. Enjoy local wines at the charming La Casona del Vino or dance the night away at the popular Club Santa Cruz. For a relaxed vibe, unwind at Café de la Plaza while soaking in the local atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in Santa Cruz

Santa Cruz, in the O'Higgins Region of Chile, offers a delightful blend of romance, entertainment, and outdoor adventures. Explore its charming attractions, vibrant piazzas, and rich history museums that provide a taste of local culture and city life. Don't miss out on optional activities like visiting Santa Cruz County, the beach, or nearby Santa Barbara to make your vacation even more memorable.

  • Colchagua Campo y Vino: Experience the serene beauty of the Colchagua Valley at this luxury attraction, where you can indulge in relaxing excursions among vineyards. Taste exquisite wines and enjoy the breathtaking landscapes that define this renowned wine region.
  • Museo de Colchagua: Dive into the rich cultural heritage of Chile at this history museum. With its extensive collections of artifacts and exhibits, you'll gain insight into the region's historical significance and the traditions that shape its identity.
  • Plaza de Armas: The heart of Santa Cruz, this vibrant square is perfect for soaking up local culture. Enjoy leisurely strolls, admire historical architecture, and immerse yourself in the lively atmosphere, making it a great spot for people-watching and relaxation.

Best time to go to Santa Cruz

The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in January, when visitor numbers are slightly high and weather is sunny with no rain. The coolest average temperature in Santa Cruz falls in July, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January72.5°F (22.5°C)No RainSunnySlightly HighAverage
February71.6°F (22.0°C)No RainSunnySlightly HighAverage
March68.4°F (20.2°C)No RainSunnySlightly HighSlightly Low
April61.5°F (16.4°C)No RainSunnyAverageSlightly High
May55.2°F (12.9°C)Light RainMostly SunnySlightly LowSlightly High
June49.6°F (9.8°C)Light RainMostly SunnyAverageAverage
July47.5°F (8.6°C)Light RainMostly SunnyAverageAverage
August50.0°F (10.0°C)Light RainMostly SunnyAverageSlightly Low
September53.2°F (11.8°C)Light RainMostly SunnyAverageAverage
October57.9°F (14.4°C)No RainSunnySlightly LowSlightly High
November64.6°F (18.1°C)No RainSunnySlightly LowAverage
December69.3°F (20.7°C)No RainSunnyAverageSlightly Low

Tips to save on your trip to Santa Cruz

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Santa Cruz.
  • Consider traveling during the off-peak season (typically March, August and December) for more affordable package holidays to Santa Cruz.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Santa Cruz Essential Information

Language
Spanish
Currency
Chilean pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
33,300
Max Temp Winter
60ºF
Max Temp Summer
90ºF
Top Sights
Lapostolle Clos Apalta Winery, MontGras Winery and Museo de Colchagua

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Frequently asked questions

What is the best time to go to Santa Cruz?
The best time to go for a Santa Cruz vacation package is generally from December through May. This period avoids the rainy season, which typically occurs between June and November, allowing travelers to enjoy the region's temperate warm climate for exploring vineyards and outdoor attractions.
How can I save money on a Santa Cruz vacation package?
When you bundle, you can save up to 30%*. To save money on a Santa Cruz package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.
What's included in a Santa Cruz vacation package?
A Santa Cruz vacation package lets you combine round-trip flights, a hotel stay, and a rental car. Many hotels in the area offer airport shuttle service to and from Santiago (SCL-Arturo Merino Benitez) for convenience, and many also include free breakfast, providing a relaxed start to your day without extra planning.Exactly what's included will vary by hotel and package, so it's worth reviewing the details before you confirm your booking.
What's the best vacation package for Santa Cruz?
For couples seeking the best vacation packages in Santa Cruz, a stay at Hotel Cava Colchagua is a strong choice. This 4-star property, rated 8.8 out of 10, offers a spa and a bar/lounge, with travelers often praising the attentive staff and fantastic food.Families can build a Santa Cruz vacation package around Santa Cruz Plaza. This 4-star hotel, rated 8.6 out of 10, features family rooms, a kids club, and an outdoor pool, making it convenient for those traveling with children. Guests frequently highlight the comfortable rooms and helpful staff.For travelers looking for great value, consider a package with a stay at Casa Calfu. Rated 9.1 out of 10, this hotel provides an outdoor pool and free breakfast, and travelers often note the kindness of the staff and delicious breakfast.
Is Santa Cruz a good choice for a family vacation package?
Santa Cruz can be a good choice for family vacation packages, especially for those interested in cultural and outdoor experiences. Some hotels offer amenities like kids clubs and family rooms to accommodate younger travelers.The 4-star Santa Cruz Plaza, rated 8.6 out of 10 by travelers, is a family-friendly hotel featuring a kids club, outdoor pool, and family rooms, making it a comfortable base for your trip. Travelers praise its delicious food and comfortable rooms.For family outings, the Museo de Colchagua, about a 5-minute walk from central Santa Cruz, offers engaging historical exhibits. You can also explore Hacienda El Huique, a historic estate about 4 miles from central Santa Cruz, which provides a glimpse into the region's past.
What are the top things to do in Santa Cruz?
A Santa Cruz vacation offers a blend of cultural exploration and renowned wine experiences:Browse and book things to do in Santa Cruz on Expedia.
Do you need to rent a car in Santa Cruz, or is public transport enough?
For a Santa Cruz vacation package, renting a car offers the most flexibility, especially since the region is an outdoor and nature destination with attractions spread out. While some hotels, like the Santa Cruz Plaza and La Perla Hotel, offer airport shuttle services to and from Santiago (SCL-Arturo Merino Benitez) Airport, which is about 90 miles away, a car allows for easier exploration of the surrounding wine country and historic sites.Many hotels in Santa Cruz provide on-site dining and activities, so a car isn't strictly necessary for daily needs if you plan to stay mostly at your accommodation. However, to visit attractions such as Lapostolle Clos Apalta Winery (about 8 miles from central Santa Cruz), Viña Vik (about 16 miles away), or Hacienda El Huique (about 4 miles away), a rental car or organized tours are highly recommended for convenient access.
Are Santa Cruz vacation package hotels conveniently located?
Santa Cruz vacation package hotels are generally well-located, with many properties within easy reach of the town's central area. This makes it convenient to explore local attractions and dining.For example, the 4-star Santa Cruz Plaza, rated 8.6 out of 10, is about a 5-minute walk from central Santa Cruz, and travelers frequently praise the helpful staff and comfortable rooms. Casa Calfu, rated 9.1 out of 10, is also centrally located, about a 10-minute walk away, with travelers praising the pool and the kindness of the staff. Further out, Hotel Boutique Grand Cru, rated 9.2 out of 10, is about 2 miles from central Santa Cruz, offering a more secluded stay while still being accessible to the area's vineyards.
Can I change or cancel my Santa Cruz vacation package if my plans change?
Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.
Do One Key members get extra savings when booking Santa Cruz vacation packages?
Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.
Does Expedia offer Book Now, Pay Later Santa Cruz vacation packages?
Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Santa Cruz vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.
How do I find last-minute vacation packages to Santa Cruz?
To find last-minute vacation packages to Santa Cruz, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.
How does free cancellation work on Santa Cruz vacation packages?
Free cancellation on a Santa Cruz vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.
Is it cheaper to book a Santa Cruz vacation as a package or separately?
Booking flights and hotels together can unlock lower overall prices. Better still, you can tailor your Santa Cruz getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
Why should I book my Santa Cruz vacation package with Expedia?
Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.