Santa Isabel

Travel Guide

A church with a bell tower, surrounded by trees and buildings.

A town with a prominent church, surrounded by greenery and mountains in the background.

An aerial view of a town with a mix of residential and commercial buildings, a prominent church, and a central plaza with a gazebo.

Visit Santa Isabel

Borunda Suites

54 C. Centenario Santa Isabel CHIH

$38 nightly

$46 total

Nov 1 - Nov 2

Total with taxes and fees

Stay at this hotel in Santa Isabel. Enjoy free WiFi, free parking, and housekeeping.

6/10 (2 reviews)

"We couldn’t locate the exact location and I called the hotel and they directed me the right place. Very easy access. Super clean. Looks like the pictures. We’ll come back for sure."

Reviewed on May 17, 2026

Hotel María Bonita Chihuahua

Periferico de la juventud 4114 Chihuahua CHIH

$96 nightly

$117 total

Nov 30 - Dec 1

Total with taxes and fees

Book a stay at this business-friendly hotel in Chihuahua. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Distrito Uno and District 1 ...

9.4/10 Exceptional! (1,886 reviews)

"Hotel ubicado cerca de D1, Personal muy atento. Restaurante y Bar dentro de las instalaciones. Fácil Acceso a Avenidas importantes Cuarto grande y limpio."

Reviewed on Oct 28, 2026

Hotel Sicomoro

Boulevard Antonio Ortiz Mena 411 Chihuahua CHIH

$51 nightly

$61 total

Nov 6 - Nov 7

Total with taxes and fees

Book a stay at this business-friendly hotel in Chihuahua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

8.8/10 Excellent! (1,088 reviews)

"Todo bien.. solo un poco viejo"

Reviewed on Oct 27, 2026

See all 81 properties in Santa Isabel

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Extended Suites Chihuahua La Juventud

Maria Montessori Lt. 1 y 2 #4102 Chihuahua CHIH

Stay at this aparthotel in Chihuahua. Enjoy free parking, a 24-hour health club, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. ...

8.6/10 Excellent! (1,465 reviews)

"Este es un hotel que podrías comparar con rentar un departamento la limpieza artículos como crema , jabón café todo lo que un hotel regular te ofrece pues aqui preferible llevar. Los empleados nada atentos paresee"

Reviewed on Oct 29, 2026

Casa Rebeca3 Complete, ideal for large groups, work teams, vacations, etc.

Chihuahua Chih.

Stay at this vacation home in Chihuahua. Enjoy air conditioning. Popular attractions El Palomar Park and Semilla Museum of Science and Technology are located ...

Outdoor Jacuzzi with FirePit and perfect location

Chihuahua Chih.

Stay at this vacation home in Chihuahua. Enjoy free WiFi, patios, and an in-room coffeemaker. Popular attractions District 1 - Shopping Mall and Cathedral of ...

8/10 Very Good! (1 review)

"It was a great little place. The only thing was was that there wasn't enough towels available in the bathrooms or the kitchen.It would also be nice to have instructions in English for how to turn on the air conditioning, etc."

Reviewed on Jul 20, 2026

See all properties in Santa Isabel

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check Santa Isabel hotel availability

Frequently asked questions

When is the best time to visit Santa Isabel?

The best time to visit Santa Isabel is from October through February, when the climate is most pleasant. For travelers seeking fewer crowds and better value, the quieter months of June through July are a good option, typically offering warmer weather.

Can I book a refundable hotel in Santa Isabel?

Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Santa Isabel by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.

Why book a trip to Santa Isabel with Expedia?

Expedia makes it easier to plan your Santa Isabel trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.

Should I stay in a hotel or vacation rental in Santa Isabel?

The best choice depends on your travel style. Hotels in Santa Isabel can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.

How can I manage my Santa Isabel trip on Expedia?

Once you've booked your Santa Isabel trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.

What if I need help during my Santa Isabel trip?

Expedia offers customer support before, during, and after your Santa Isabel trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.

How can Expedia help me plan my first trip to Santa Isabel?

If it's your first trip to Santa Isabel, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.

How can I save on my Santa Isabel hotel booking with Expedia?

Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Santa Isabel hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.