Title: Santee Vacation Packages 2026 from $460 | Expedia.com [Santee Travel Guide](https://expedia.com/Santee.dx9953)[Hotels in Santee](https://expedia.com/Santee-Hotels.d9953.Travel-Guide-Hotels)[Vacation Rentals in Santee](https://expedia.com/Santee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.com/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Car Rentals in Santee](https://expedia.com/Car-Rentals-In-Santee.d9953.Car-Rental-Guide) ![](https://images.trvl-media.com/place/9953/712fb946-715a-4a74-8bf7-2c2bbd891023.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santee Vacations from $460 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Santee Vacation Enjoy unforgettable adventures when you book a vacation package to Santee. Whether you're a foodie, art buff or just a traveler who loves discovering new places, there's something for everyone in this lively city. If your trip to Santee includes some sightseeing, don't miss famous attractions like [Santee State Park](https://www.expedia.com/Santee-State-Park-Santee.d6140632.Vacation-Attraction), [Santee Cooper Country Club](https://www.expedia.com/Santee-Cooper-Country-Club-Santee.d553248621532654899.Vacation-Attraction) and [Santee Outlets](https://www.expedia.com/Santee-Outlets-Santee.d6140634.Vacation-Attraction). Stop daydreaming and start traveling. Browse the many options on Expedia today and put your Santee vacation plans into action! ## The Latest Santee vacation packages Price found within the past 48 hours. Click for updated prices. ![stayAPT Suites Columbia-Irmo Harbison](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/b733a543_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### stayAPT Suites Columbia-Irmo Harbison $460 per person May 2 - May 6 found 1 day ago Roundtrip non-stop flight included New York (JFK) to Columbia (CAE) 8.6/10 Excellent! (323 reviews) Everything about the facility was fantastic!! Reviewed on Feb 20, 2026 ![Hyatt Place Columbia/Downtown/The Vista](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690567/c2bace01_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Place Columbia/Downtown/The Vista Downtown Columbia $511 per person May 2 - May 6 found 1 day ago Roundtrip non-stop flight included New York (JFK) to Columbia (CAE) 8.6/10 Excellent! (1,001 reviews) Amenities. The coffee was only decaf, didn’t like the glass bathroom door and our view wasn’t very good and didn’t like being charged $20.00 to park my vehicle after paying for a room I think parking should be free. Reviewed on Feb 25, 2026 ![Holiday Inn Express & Suites Columbia Downtown - The Vista by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619514/04825b57_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Holiday Inn Express & Suites Columbia Downtown - The Vista by IHG Downtown Columbia $567 per person May 2 - May 6 found 1 day ago Roundtrip non-stop flight included New York (JFK) to Columbia (CAE) 8.8/10 Excellent! (700 reviews) Great front desk. Good value Reviewed on Feb 25, 2026 ![Residence Inn by Marriott Columbia Northeast/Fort Jackson Area](https://images.trvl-media.com/lodging/2000000/1240000/1236800/1236733/c3cdc4d8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Residence Inn by Marriott Columbia Northeast/Fort Jackson Area $764 per person Apr 6 - Apr 10 found 1 day ago Roundtrip flight included New York (NYC) to Columbia (CAE) 9/10 Wonderful! (781 reviews) Good stay. Hotel starting to show its age. Reviewed on Jan 20, 2026 ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](https://images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG $473 per person Apr 14 - Apr 17 found 1 day ago Roundtrip non-stop flight included Newark Liberty Intl. Airport (EWR) to Columbia (CAE) 8.8/10 Excellent! (1,003 reviews) The room and the staff were great Reviewed on Feb 23, 2026 Don't see what you're looking for? See all available trips from Columbus to Santee [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-27/2026-04-03/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=CAE&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_9953) ### Discover the most popular places to visit in Santee #### Santee State Park You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants. [](https://expedia.com/Santee-State-Park-Santee.d6140632.Vacation-Attraction) #### Santee Cooper Country Club Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants. [](https://expedia.com/Santee-Cooper-Country-Club-Santee.d553248621532654899.Vacation-Attraction) #### Santee National Golf Club Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants. [](https://expedia.com/Santee-National-Golf-Club-Santee.d553248621532654897.Vacation-Attraction) ## Santee Hotel Deals ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St. Santee SC Fully refundableReserve now, pay when you stay $109 nightly $121 total Mar 5 - Mar 6 Total with taxes and fees 9.2/10 Wonderful! (738 reviews) Our room was very clean and comfortable . Quiet except for mild traffic noise. A plus - a Cracker Barrel next door for an easy walk. Reviewed on Feb 26, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&selected=92600969&PinnedHotelID=92600969&HadPinnedHotel=true®ionId=9953) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Baymont by Wyndham Santee 249 Britain Street Santee SC Fully refundableReserve now, pay when you stay $80 nightly $89 total Mar 1 - Mar 2 Total with taxes and fees 8/10 Very Good! (1,425 reviews) Room clean. Convenient location. Quick check in. Reviewed on Feb 25, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=15379&PinnedHotelID=15379&HadPinnedHotel=true®ionId=9953) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fairfield Inn & Suites by Marriott Santee 9074 Old Number Six Hwy Santee SC Fully refundableReserve now, pay when you stay $125 nightly $139 total Mar 8 - Mar 9 Total with taxes and fees 9.8/10 Exceptional! (1,003 reviews) This will definitely be our new place to stay on our way back-and-forth to North Carolina from Florida! Reviewed on Feb 25, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=26116&PinnedHotelID=26116&HadPinnedHotel=true®ionId=9953) [See all 306 properties in Santee](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F28%2F2026&endDate=3%2F1%2F2026®ionId=9953) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Santee Vacation Packages ## Santee Essential Information | Language | English | | --------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | U.S dollars | | Population | 940 | | Max Temp Winter | 55ºF | | Max Temp Summer | 90ºF | | Top Sights | [Santee State Park](https://www.expedia.com/Santee-State-Park-Santee.d6140632.Vacation-Attraction), [Santee Cooper Country Club](https://www.expedia.com/Santee-Cooper-Country-Club-Santee.d553248621532654899.Vacation-Attraction) and [Santee National Golf Club](https://www.expedia.com/Santee-National-Golf-Club-Santee.d553248621532654897.Vacation-Attraction) | ## More vacations 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[](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does a Santee vacation package cost? ### What are the cheapest months to go to Santee? ### How many days is enough for Santee? ### Is it worth booking a vacation package to Santee? ### How to find the best Santee package deals? ### Is it cheaper to book a Santee vacation as a package? ### When to book a vacation package to Santee? ### Does Expedia offer Book Now, Pay Later Santee vacation packages? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Santee Cooper Country Club 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