Title: Semmes Vacation Rentals from $146: Search Short-Term Rentals | Expedia.com [Semmes Travel Guide](https://expedia.com/Semmes.dx6340053)[Hotels in Semmes](https://expedia.com/Semmes-Hotels.d6340053.Travel-Guide-Hotels)[Flights to Semmes](https://expedia.com/Cheap-Flights-To-Semmes.d6340053.Travel-Guide-Flights)[Car Rentals in Semmes](https://expedia.com/Car-Rentals-In-Semmes.d6340053.Car-Rental-Guide)[Semmes Vacation Packages](https://expedia.com/Semmes.d6340053.Destination-Travel-Guides) ![Indian azaleas (Rhododendron indicum) bloom at a public park in Mobile Alabama](https://images.trvl-media.com/place/6340053/7351254f-50ff-456c-a846-d436293aebf0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6340053/7351254f-50ff-456c-a846-d436293aebf0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check prices for these dates In two weeks [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6340053&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 15 - May 17](https://www.expedia.com/Hotel-Search?regionId=6340053&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 12 - Jun 14](https://www.expedia.com/Hotel-Search?regionId=6340053&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 10 - Jul 12](https://www.expedia.com/Hotel-Search?regionId=6340053&startDate=2026-07-10&endDate=2026-07-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Semmes vacation rentals ![Microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/125000000/124110000/124106000/124105989/85b5baca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124110000/124106000/124105989/cdcc3804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/125000000/124110000/124106000/124105989/5b519b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124110000/124106000/124105989/9fa8ffae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom house in Semmes with cool AC breeze [](https://www.expedia.com/Semmes-Hotels-Charming-3-Bedroom-House-In-Semmes-With-Cool-AC-Breeze.h124105989.Hotel-Information) Semmes 6.0/10 (2 reviews) "Overall the owners were nice and respectful. They answered all the questions we asked and the place was beautiful. I would definitely book again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cecelia P. $294 nightly $315 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Semmes-Hotels-Charming-3-Bedroom-House-In-Semmes-With-Cool-AC-Breeze.h124105989.Hotel-Information) ![Smart TV, books](https://images.trvl-media.com/lodging/84000000/83470000/83466000/83465992/97c3767b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83470000/83466000/83465992/687fdead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, bidet, towels](https://images.trvl-media.com/lodging/84000000/83470000/83466000/83465992/9c1afd2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/84000000/83470000/83466000/83465992/0cfae7b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grandbay Oasis [](https://www.expedia.com/Grand-Bay-Hotels-Grandbay-Oasis.h83465992.Hotel-Information) Grand Bay 9.0/10 Wonderful (10 reviews) "Cozy with ample parking Host was very responsive" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald N. $246 nightly $270 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Grand-Bay-Hotels-Grandbay-Oasis.h83465992.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/118000000/117230000/117224200/117224101/00d76713.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/118000000/117230000/117224200/117224101/4beb9cf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117230000/117224200/117224101/c9886a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/118000000/117230000/117224200/117224101/a0f757d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 2-BR MH in wonderful country setting. Short drive to Industrial Plants [](https://www.expedia.com/Chunchula-Hotels-Cozy-2-BR-MH-In-Wonderful-Country-Setting-Short-Drive-To-Industrial-Plants.h117224101.Hotel-Information) Chunchula $251 nightly $265 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Chunchula-Hotels-Cozy-2-BR-MH-In-Wonderful-Country-Setting-Short-Drive-To-Industrial-Plants.h117224101.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/128000000/127160000/127156500/127156405/e77fd435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/128000000/127160000/127156500/127156405/843b6b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/128000000/127160000/127156500/127156405/f0a65f9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/128000000/127160000/127156500/127156405/cfbc3a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### fully set up camper ready to go, located at Homestead RV Community park [](https://www.expedia.com/Theodore-Hotels-Fully-Set-Up-Camper-Ready-To-Go.h127156405.Hotel-Information) Theodore $118 nightly $123 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/Theodore-Hotels-Fully-Set-Up-Camper-Ready-To-Go.h127156405.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/71000000/70060000/70056200/70056104/45a76355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/71000000/70060000/70056200/70056104/94fde360.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, bed sheets](https://images.trvl-media.com/lodging/71000000/70060000/70056200/70056104/749074e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70060000/70056200/70056104/230579a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rustic Cabin Overlooking Private 48 acre Bass Fishing Lake [](https://www.expedia.com/Lucedale-Hotels-Rustic-Cabin-Overlooking-Private-48-Acre-Bass-Fishing-Lake.h70056104.Hotel-Information) Lucedale 9.6/10 Exceptional (271 reviews) "We love this little cabin" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Southern S. $209 nightly $224 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Lucedale-Hotels-Rustic-Cabin-Overlooking-Private-48-Acre-Bass-Fishing-Lake.h70056104.Hotel-Information) ![1 bedroom, desk, iron/ironing board, internet](https://images.trvl-media.com/lodging/123000000/122190000/122184800/122184769/8f177596.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/123000000/122190000/122184800/122184769/c525539a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/123000000/122190000/122184800/122184769/190fadc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/123000000/122190000/122184800/122184769/d4028c46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Copper Den Condo by the Bay, Chic & Cozy studio [](https://www.expedia.com/Daphne-Hotels-Copper-Den-Condo-By-The-Bay.h122184769.Hotel-Information) Daphne $218 nightly $240 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Daphne-Hotels-Copper-Den-Condo-By-The-Bay.h122184769.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/79000000/78570000/78562500/78562425/e0816cfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/79000000/78570000/78562500/78562425/6beefc53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/79000000/78570000/78562500/78562425/3361896f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/79000000/78570000/78562500/78562425/0d20c7d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DAPHNE - MOBILE BAY CONDO - Great location [](https://www.expedia.com/Daphne-Hotels-DAPHNE-MOBILE-BAY-CONDO-COMFORTABLE-AND-CONVENIENT.h78562425.Hotel-Information) Daphne 9.8/10 Exceptional (80 reviews) "Host was very understanding and the place was excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ethan B. $184 nightly $202 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Daphne-Hotels-DAPHNE-MOBILE-BAY-CONDO-COMFORTABLE-AND-CONVENIENT.h78562425.Hotel-Information) ![Fridge, cookware/dishes/utensils, ice maker](https://images.trvl-media.com/lodging/91000000/90250000/90246600/90246537/144d72fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90250000/90246600/90246537/feb6d90a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/91000000/90250000/90246600/90246537/0b17c603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/91000000/90250000/90246600/90246537/ee1cf3ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### House in Mobile Newly Renovated! Quiet street & centrally located to interstate! [](https://www.expedia.com/Mobile-Hotels-House-In-Mobile-Newly-Renovated-Quiet-Street-Centrally-Located-To-Interstate.h90246537.Hotel-Information) Mobile 9.2/10 Wonderful (19 reviews) "Charming, comfortable, clean vacation stay which has everything you need. We enjoyed the quiet neighborhood which was near downtown." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Noel S. $219 nightly $253 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Mobile-Hotels-House-In-Mobile-Newly-Renovated-Quiet-Street-Centrally-Located-To-Interstate.h90246537.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/106000000/105400000/105399500/105399421/9f0c8fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105400000/105399500/105399421/f721b192.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, City View | Garden view](https://images.trvl-media.com/lodging/106000000/105400000/105399500/105399421/125e0301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, City View | View from room](https://images.trvl-media.com/lodging/106000000/105400000/105399500/105399421/02d16ca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Downtown Cozy 2 BR Apt - 4min drive MardiGras Park [](https://www.expedia.com/Mobile-Hotels-Top-Of-The-Bay-01.h105399421.Hotel-Information) Mobile Central Business District 9.4/10 Exceptional (3 reviews) "Everything was wonderful. The location is great for Mardi Gras!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maggie $284 nightly $334 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Mobile-Hotels-Top-Of-The-Bay-01.h105399421.Hotel-Information) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107170000/107167700/107167602/788d713d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107170000/107167700/107167602/ee359be6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107170000/107167700/107167602/5410a75d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/108000000/107170000/107167700/107167602/598863aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bay Getaway, Cozy Studio Condominium in Daphne, AL - Sleeps 2 - Near Interstate [](https://www.expedia.com/Daphne-Hotels-Bay-Getaway.h107167602.Hotel-Information) Daphne 10/10 Exceptional (36 reviews) "The host was nice and place was clean! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan A. $169 nightly $186 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/Daphne-Hotels-Bay-Getaway.h107167602.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/19000000/18770000/18762400/18762309/3bda70ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18770000/18762400/18762309/ad4a4dde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/19000000/18770000/18762400/18762309/f2a21482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18770000/18762400/18762309/700ea87b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Charming Small Apartment [](https://www.expedia.com/Mobile-Hotels-Nice-Quiet-Charming-Apt-In-Historical-Mobile.h18762309.Hotel-Information) The Loop 9.6/10 Exceptional (58 reviews) "Convenient location for everything that we did while in Mobile " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julia T. $145 nightly $167 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Mobile-Hotels-Nice-Quiet-Charming-Apt-In-Historical-Mobile.h18762309.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/75000000/74890000/74884600/74884527/3bf83775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/75000000/74890000/74884600/74884527/34c26c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/75000000/74890000/74884600/74884527/51e38cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/75000000/74890000/74884600/74884527/ca87a15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bon Aire Apartment is in downtown Mobile on the Mardi Gras Parade Route [](https://www.expedia.com/Mobile-Hotels-Mardi-Gras-Efficiency-Apartment-On-The-Parade-Route.h74884527.Hotel-Information) Washington Square 9.8/10 Exceptional (64 reviews) "Great time at our VRBO! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Elizabeth H. $170 nightly $196 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Mobile-Hotels-Mardi-Gras-Efficiency-Apartment-On-The-Parade-Route.h74884527.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/115000000/114340000/114330600/114330567/ca8801bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/115000000/114340000/114330600/114330567/e5f2e0f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/115000000/114340000/114330600/114330567/d60b9465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114340000/114330600/114330567/1d5e70d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish Home | Sleep 6 | Mid Town [](https://www.expedia.com/Mobile-Hotels-Stylish-Home-Sleep-6-Mid-Town.h114330567.Hotel-Information) Dauphin Acres 9.4/10 Exceptional (3 reviews) "This was so much better than a hotel. Screaming fast wifi, open floor plan. big, comfortable beds and good communication. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott K. $213 nightly $213 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Mobile-Hotels-Stylish-Home-Sleep-6-Mid-Town.h114330567.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/113000000/112610000/112608800/112608773/104c7f4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/113000000/112610000/112608800/112608773/22735b39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112610000/112608800/112608773/3e1fdafb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112610000/112608800/112608773/eb8ec50e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom cottage with WiFi, AC nears parks and shopping [](https://www.expedia.com/Mobile-Hotels-Charming-3-Bedroom-Cottage-With-WiFi.h112608773.Hotel-Information) Mobile 9.8/10 Exceptional (6 reviews) "The host was amazing very clean and beautiful property close to everything. The set up and welcome was great i would definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Welton M. $201 nightly $233 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Mobile-Hotels-Charming-3-Bedroom-Cottage-With-WiFi.h112608773.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108940000/108935300/108935261/edd55115.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/109000000/108940000/108935300/108935261/adbc0c17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/109000000/108940000/108935300/108935261/w1919h1080x1y0-0849b884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108940000/108935300/108935261/w1919h1080x1y0-90fd8028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1 bedroom at Oak + Fountain - #8 [](https://www.expedia.com/Grand-Bay-Hotels-1-Bedroom-At-Oak-Fountain-8.h108935261.Hotel-Information) Grand Bay 8.8/10 Excellent (6 reviews) "Very peaceful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dangel S. $140 nightly $149 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Grand-Bay-Hotels-1-Bedroom-At-Oak-Fountain-8.h108935261.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/97000000/96880000/96870500/96870411/7c45f67d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/97000000/96880000/96870500/96870411/00d92751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, video games, DVD player](https://images.trvl-media.com/lodging/97000000/96880000/96870500/96870411/d3749edb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96880000/96870500/96870411/dc484753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded cabin on the water with jetski, hottub & kayak! Pets OK & early checkin [](https://www.expedia.com/Satsuma-Hotels-Secluded-Cabin-On-The-Water-With-Jetski.h96870411.Hotel-Information) Satsuma 9.6/10 Exceptional (25 reviews) "It was just what we needed, a relaxing weekend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lewis P. $338 nightly $373 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Satsuma-Hotels-Secluded-Cabin-On-The-Water-With-Jetski.h96870411.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120840000/120831300/120831261/9511883d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/121000000/120840000/120831300/120831261/7a3def47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120840000/120831300/120831261/b8e53c96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120840000/120831300/120831261/bc0f6393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfortable 2BR Escape | Walk to MOB [](https://www.expedia.com/Mobile-Hotels-Inviting-2BR-Stay-Close-To-MOB.h120831261.Hotel-Information) Mobile $273 nightly $307 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Mobile-Hotels-Inviting-2BR-Stay-Close-To-MOB.h120831261.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/117000000/116790000/116784600/116784560/w1200h799x0y1-97741cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/117000000/116790000/116784600/116784560/w1280h898x0y0-68047ab5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116790000/116784600/116784560/w1199h799x1y1-d4bc6dce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/117000000/116790000/116784600/116784560/w1199h799x1y1-8445d621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Stylish Home, 5 min walk to downtown Mobile [](https://www.expedia.com/Mobile-Hotels-Historic-Montegeux-Cottage-Pet-Friendly.h116784560.Hotel-Information) Old Dauphin Way Historic District 9.8/10 Exceptional (15 reviews) "Property was convenient to everything we wanted to see and do. Super dog friendly and very well maintained " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wes B. $279 nightly $322 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Mobile-Hotels-Historic-Montegeux-Cottage-Pet-Friendly.h116784560.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/128000000/127090000/127089100/127089100/7f8f066b_edited_5339.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127090000/127089100/127089100/d3e1aefc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/128000000/127090000/127089100/127089100/b78bfe30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, toilet paper](https://images.trvl-media.com/lodging/128000000/127090000/127089100/127089100/2c63bdb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gorgeous 3-bedroom house with AC in delightful Mobile [](https://www.expedia.com/Mobile-Hotels-Gorgeous-3-Bedroom-House-With-AC-In-Delightful-Mobile.h127089100.Hotel-Information) Mobile $218 nightly $252 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Mobile-Hotels-Gorgeous-3-Bedroom-House-With-AC-In-Delightful-Mobile.h127089100.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/19000000/18770000/18764000/18763920/b2c6c099.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/19000000/18770000/18764000/18763920/06ef1329.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/19000000/18770000/18764000/18763920/817aaef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18770000/18764000/18763920/2b09f21e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Small Studio Condo -Private balcony -Free Parking [](https://www.expedia.com/Mobile-Hotels-Small-Studio-Condo-With-Private-Balcony.h18763920.Hotel-Information) Old Dauphin Way Historic District 9.4/10 Exceptional (110 reviews) "I would definitely stay here again in the future" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Phillip F. $138 nightly $158 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Mobile-Hotels-Small-Studio-Condo-With-Private-Balcony.h18763920.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-04®ionId=6340053&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.com/Hotel-Search?destination=Semmes%2C+Alabama%2C+United+States+of+America®ionId=6340053&latLong=30.769097%2C-88.274738&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=CABIN) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Semmes%2C+Alabama%2C+United+States+of+America®ionId=6340053&latLong=30.769097%2C-88.274738&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=VACATION_HOME) Cottages [](https://www.expedia.com/Hotel-Search?destination=Semmes%2C+Alabama%2C+United+States+of+America®ionId=6340053&latLong=30.769097%2C-88.274738&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=COTTAGE) Apartments [](https://www.expedia.com/Hotel-Search?destination=Semmes%2C+Alabama%2C+United+States+of+America®ionId=6340053&latLong=30.769097%2C-88.274738&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=APARTMENT) Condos [](https://www.expedia.com/Hotel-Search?destination=Semmes%2C+Alabama%2C+United+States+of+America®ionId=6340053&latLong=30.769097%2C-88.274738&adults=2&startDate=2026-06-18&d1=2026-06-18&endDate=2026-06-21&d2=2026-06-21&lodging=CONDO) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSemmes-Vacation-Rentals.d6340053.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSemmes-Vacation-Rentals.d6340053.Travel-Guide-VacationRentals) ## Top Semmes Hotel Reviews ![Hilton Garden Inn Mobile West I-65/Airport Blvd](https://images.trvl-media.com/lodging/2000000/1860000/1853300/1853241/b4700d08_y.jpg) ### Hilton Garden Inn Mobile West I-65/Airport Blvd 8/10 Good "Nice property.Located near interstate and mall Only issue was someone set off the firearm." [](https://expedia.com/Mobile-Hotels-Hilton-Garden-Inn-Mobile-West-I-65Airport-Blvd.h1853241.Hotel-Information) ![Comfort Suites Daphne - Mobile East Bay](https://images.trvl-media.com/lodging/1000000/160000/159200/159188/622173a7_y.jpg) ### Comfort Suites Daphne - Mobile East Bay 6/10 Okay "The staff was friendly. It’s the property itself. I believe the property needs a complete remodel. It’s old and dated and there’s a odor of mildew." [](https://expedia.com/Mobile-Hotels-Comfort-Suites-Mobile-East-Bay.h159188.Hotel-Information) ![Best Western Plus Mobile Inn & Suites](https://images.trvl-media.com/lodging/95000000/94680000/94672600/94672573/66b130f2_y.jpg) ### Best Western Plus Mobile Inn & Suites 6/10 Okay "There are a lot of shops and restaurants near by." [](https://expedia.com/Mobile-Hotels-Best-Western-Plus-Mobile-Inn-Suites.h94672573.Hotel-Information) ![Tru by Hilton Mobile](https://images.trvl-media.com/lodging/39000000/38530000/38521000/38520999/c322b6ce_y.jpg) ### Tru by Hilton Mobile 10/10 Excellent "Everything was perfect " [](https://expedia.com/Mobile-Hotels-Tru-By-Hilton-Mobile.h38520999.Hotel-Information) ![Holiday Inn Mobile-Dwtn/Hist. District by IHG](https://images.trvl-media.com/lodging/1000000/20000/11600/11551/ac4f55f4_y.jpg) ### Holiday Inn Mobile-Dwtn/Hist. District by IHG 6/10 Okay "Wouldn't stay here again. " [](https://expedia.com/Mobile-Hotels-Holiday-Inn-Mobile-DwtnHist-District.h11551.Hotel-Information) ![Renaissance Mobile Riverview Plaza Hotel](https://images.trvl-media.com/lodging/1000000/10000/5700/5616/62ad1f78_y.jpg) ### Renaissance Mobile Riverview Plaza Hotel 10/10 Excellent "Super nice riverview room, convenient location. Staff and valet were pleasant and attentive. Of three hotels used during out travels, this one was heads above the rest." [](https://expedia.com/Mobile-Hotels-Renaissance-Mobile-Riverview-Plaza-Hotel.h5616.Hotel-Information) ![Holiday Inn Express & Suites Mobile West I-10 by IHG](https://images.trvl-media.com/lodging/3000000/2390000/2385400/2385345/0c38b924_y.jpg) ### Holiday Inn Express & Suites Mobile West I-10 by IHG 8/10 Good "Everything was great " [](https://expedia.com/Mobile-Hotels-Holiday-Inn-Express-Suites-Mobile-West-I-10.h2385345.Hotel-Information) ![Courtyard by Marriott Mobile Daphne/Eastern Shore](https://images.trvl-media.com/lodging/3000000/2360000/2350400/2350368/fb227fe4_y.jpg) ### Courtyard by Marriott Mobile Daphne/Eastern Shore 10/10 Excellent "Great" [](https://expedia.com/Mobile-Hotels-Courtyard-By-Marriott-Mobile-DaphneEastern-Shore.h2350368.Hotel-Information) ![Quality Inn & Suites at Airport Blvd I-65](https://images.trvl-media.com/lodging/1000000/60000/50300/50264/20b6881d_y.jpg) ### Quality Inn & Suites at Airport Blvd I-65 10/10 Excellent "The room was clean and the showers were hot. Checking in and out was easy and accommodating. The staff were very polite and helpful. The location of the Hotel is in an area where restaurants, gas stations and grocery stores are within a close driving distance usually a few minutes. For the price point, you received good quality/value. " [](https://expedia.com/Mobile-Hotels-Quality-Inn-Suites-At-Airport-Blvd-I-65.h50264.Hotel-Information) ## Find out more about Semmes **Everything you need to know about Semmes vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Semmes vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Semmes vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Semmes vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Semmes. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Semmes in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $146 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Semmes rentals** At Expedia, we put the best Semmes vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Semmes rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Semmes vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Semmes. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in Semmes ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals) - [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals) - [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals) - [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals) - [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals) - [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals) - [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals) - [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals) - [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals) - [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals) - [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals) - [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals) - [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals) - [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations) - [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations) - [Vacation Homes in Semmes ](https://expedia.com/Semmes-Private-Vacation-Homes.d6340053-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in Semmes ](https://expedia.com/Semmes-Apartments.d6340053-aaApartments.Travel-Guide-Accommodation) - [Cottages in Semmes ](https://expedia.com/Semmes-Cottages.d6340053-aaCottages.Travel-Guide-Accommodation) - [Condo Rentals in Semmes ](https://expedia.com/Semmes-Condos.d6340053-aaCondos.Travel-Guide-Accommodation) - [Motels in Semmes ](https://expedia.com/Semmes-Motels.d6340053-aaMotels.Travel-Guide-Accommodation) - [Cabin Rentals in Semmes ](https://expedia.com/Semmes-Cabins.d6340053-aaCabins.Travel-Guide-Accommodation) - [Farmstay in Semmes ](https://expedia.com/Semmes-Agritourism.d6340053-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Semmes ](https://expedia.com/Semmes-Bed-And-Breakfast.d6340053-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Inns in Semmes ](https://expedia.com/Semmes-Inns.d6340053-aaInns.Travel-Guide-Accommodation) - [Guest Houses in Semmes ](https://expedia.com/Semmes-Guest-Houses.d6340053-aaGuestHouses.Travel-Guide-Accommodation) ## Frequently asked questions ### Are there vacation rentals in Semmes? ### What's the top vacation rental that Semmes has to offer? ### How many vacation rentals are there in Semmes? ### What’s there to see and do in Semmes? ### What’s a vacation rental in Semmes like? ### Expedia's Latest Trends Hotels - [Cheap Hotels in Gulf Shores](https://expedia.com/Gulf-Shores-Hotels-Cheap-Hotels.0-0-d603078-tCheapHotels.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Gulf Shores](https://expedia.com/Gulf-Shores-Hotels-Oceanfront-Hotels.0-0-d603078-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Hotels in Dauphin Island](https://expedia.com/Dauphin-Island-Hotels.d182896.Travel-Guide-Hotels) - [Oceanfront Hotels in Orange Beach](https://expedia.com/Orange-Beach-Hotels-Oceanfront-Hotels.0-0-d9136-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Hotels in Florence](https://expedia.com/Florence-Hotels.d6057726.Travel-Guide-Hotels) - [All-inclusive Resorts in Orange Beach](https://expedia.com/Orange-Beach-Hotels-All-Inclusive-Hotel.0-0-d9136-tAllinclusiveHotel.Travel-Guide-Filter-Hotels) - [Hotels in Cullman](https://expedia.com/Cullman-Hotels.d6057735.Travel-Guide-Hotels) - [Hotels in Mobile](https://expedia.com/Mobile-Hotels.d602984.Travel-Guide-Hotels) - [All-inclusive Resorts in Gulf Shores](https://expedia.com/Gulf-Shores-Hotels-All-Inclusive-Hotel.0-0-d603078-tAllinclusiveHotel.Travel-Guide-Filter-Hotels) - [Hotels in Auburn](https://expedia.com/Auburn-Hotels.d6184.Travel-Guide-Hotels) - [Hotels in Prattville](https://expedia.com/Prattville-Hotels.d9410.Travel-Guide-Hotels) - [Hotels in Gulf Shores](https://expedia.com/Gulf-Shores-Hotels.d603078.Travel-Guide-Hotels) - [Hotels in Dothan](https://expedia.com/Dothan-Hotels.d1006.Travel-Guide-Hotels) - [Hotels in Foley](https://expedia.com/Foley-Hotels.d8989.Travel-Guide-Hotels) - [Hotels in Tuscaloosa](https://expedia.com/Tuscaloosa-Hotels.d3390.Travel-Guide-Hotels) - [Hotels in Montgomery](https://expedia.com/Montgomery-Hotels.d602983.Travel-Guide-Hotels) - [Cheap Hotels in Mobile](https://expedia.com/Mobile-Hotels-Cheap-Hotels.0-0-d602984-tCheapHotels.Travel-Guide-Filter-Hotels) Flights - [Gulf Shores Flights](https://expedia.com/lp/flights/603078/flights-from-gulf-shores) - [Cheap Flights to Montgomery](https://expedia.com/Cheap-Flights-To-Montgomery.d602983.Travel-Guide-Flights) - [Cheap Flights to Mobile](https://expedia.com/Cheap-Flights-To-Mobile.d602984.Travel-Guide-Flights) - [Cheap Flights to Gulf Shores](https://expedia.com/Cheap-Flights-To-Gulf-Shores.d603078.Travel-Guide-Flights) - [Cheap Flights to Tuscaloosa](https://expedia.com/Cheap-Flights-To-Tuscaloosa.d3390.Travel-Guide-Flights) - [Cheap Flights to Orange Beach](https://expedia.com/Cheap-Flights-To-Orange-Beach.d9136.Travel-Guide-Flights) Cars - [Car rentals in Montgomery](https://expedia.com/Car-Rentals-In-Montgomery.d602983.Car-Rental-Guide) - [Car rentals in Mobile](https://expedia.com/Car-Rentals-In-Mobile.d602984.Car-Rental-Guide) Cruises - [Cruises from Mobile](https://expedia.com/Cruises-from-Mobile.d602984.Cruise-Departure-Port) Activities - [Things to do in Orange Beach](https://expedia.com/Things-To-Do-In-Orange-Beach.d9136.Travel-Guide-Activities) Packages - [Gulf Shores Vacation](https://expedia.com/Gulf-Shores.d603078.Destination-Travel-Guides) Vacation Rentals - [Gulf Shores Vacation Rentals](https://expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Orange Beach Vacation Rentals](https://expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals)