A dense cluster of vibrant pink azaleas in full bloom.

Semmes Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Sep 25 - Sep 27
In two months
Nov 6 - Nov 8
In three months
Dec 4 - Dec 6
In four months
Jan 1 - Jan 3

Our top choices for Semmes vacation rentals

A multi-story building with balconies, palm trees, and a clear sky.

1. King Bed Accessible|OYO Hotel Mobile

King Bed Accessible|OYO Hotel Mobile
Llanfair
10.0 out of 10, Exceptional, (107 reviews)
"Super convenient access to major roads but still felt peaceful and calm inside."
United States
Anonymous traveler
$63 nightly
The price is $70
Sep 30 - Oct 1
Total with taxes and fees
King Bed Accessible|OYO Hotel Mobile
A single-story brick building with a front porch, a mailbox, and a well-maintained lawn.

2. The Luxe Haven - 3BR • Huge Gated Yard • Private Patio

The Luxe Haven - 3BR • Huge Gated Yard • Private Patio
Mobile
$137 nightly
The price is $156
Sep 14 - Sep 15
Total with taxes and fees
The Luxe Haven - 3BR • Huge Gated Yard • Private Patio
A modern kitchen with white cabinets, a central island with chairs, a microwave, and a stainless steel range hood.

3. West Mobile Farmhouse Fun

West Mobile Farmhouse Fun
Mobile
$242 nightly
The price is $242
Sep 13 - Sep 14
Total with taxes and fees
West Mobile Farmhouse Fun
A living room with a white sofa, a glass coffee table, a floor lamp, and a large floral rug. There are framed pictures on the wall and a cactus plant.

4. Modern Chic 2BR | Downtown Living & Pet-Friendly

Modern Chic 2BR | Downtown Living & Pet-Friendly
Mobile
10.0 out of 10, Exceptional, (1 review)
"We were late to check in do to a storm. We contacted the owner and they was more than understanding. They even turned the porch light on for us so when we arrived we would be able to see. This was very thoughtful . The house was clean a good layout. They had rolls of trash bags complimentary waters coffee sugar and creamer for weeks if I needed to stay longer. They had enough toilet paper dish soap laundry consumables. The had silverware plates cups coffee cups cookware to cook for a army. They...
United States
Mary B.
$292 nightly
The price is $328
Sep 13 - Sep 14
Total with taxes and fees
Modern Chic 2BR | Downtown Living & Pet-Friendly
A living room with two beige sofas, a small table, a lamp, and a door.

5. Charming 3-bedroom cottage with WiFi, AC nears parks and shopping

Charming 3-bedroom cottage with WiFi, AC nears parks and shopping
Mobile
9.8 out of 10, Exceptional, (9 reviews)
"The host was amazing very clean and beautiful property close to everything. The set up and welcome was great i would definitely stay again. "
United States
Welton M.
$225 nightly
The price is $257
Oct 7 - Oct 8
Total with taxes and fees
Charming 3-bedroom cottage with WiFi, AC nears parks and shopping
A spacious living area with a gray sofa, a glass coffee table, and a ceiling fan.

6. Relax & Unwind at This Charming West Mobile Getaway! 2BR/2BA Guesthouse Retreat!

Relax & Unwind at This Charming West Mobile Getaway! 2BR/2BA Guesthouse Retreat!
Mobile
10.0 out of 10, Exceptional, (2 reviews)
"House was clean & just as listed. Host was very easy to communicate with. Would definitely recommend!!"
United States
Laurie H.
$315 nightly
The price is $345
Sep 13 - Sep 14
Total with taxes and fees
Relax & Unwind at This Charming West Mobile Getaway! 2BR/2BA Guesthouse Retreat!
A serene garden with a central water feature, surrounded by neatly trimmed hedges and blooming white flowers.

7. Private Charming Small Apartment

Private Charming Small Apartment
The Loop
9.6 out of 10, Exceptional, (64 reviews)
"Loved this apartment "
United States
Jenelle R.
$136 nightly
The price is $156
Sep 18 - Sep 19
Total with taxes and fees
Private Charming Small Apartment
A living room with a blue sofa, a white armchair, a glass coffee table, and a floral rug. There is a dining area with a wooden table and chairs, and a kitchen in the background.

8. Modern Bright 2BR Retreat | Pet-Friendly Living

Modern Bright 2BR Retreat | Pet-Friendly Living
Mobile
9.4 out of 10, Exceptional, (6 reviews)
"Great location, back yard fenced for dogs and comfortable beds."
United States
Julie Y.
$276 nightly
The price is $329
Sep 17 - Sep 18
Total with taxes and fees
Modern Bright 2BR Retreat | Pet-Friendly Living

9. 1 Bedroom Apartment at Oak + Fountain - #18

1 Bedroom Apartment at Oak + Fountain - #18
Grand Bay
10.0 out of 10, Exceptional, (1 review)
"Great property! "
United States
Travis S.
$154 nightly
The price is $163
Sep 14 - Sep 15
Total with taxes and fees
1 Bedroom Apartment at Oak + Fountain - #18
A dining area with a glass table, chairs, a chandelier, a mirror, and a painting.

10. Pet Friendly Midtown Mobile Condo

Pet Friendly Midtown Mobile Condo
Old Dauphin Way Historic District
9.0 out of 10, Wonderful, (6 reviews)
"The unit was very cute and clean. Loved the bed. Great location"
United States
April
Pet Friendly Midtown Mobile Condo
A modern living room with a sofa, a patterned rug, and a kitchen area with a stove.

11. Midtown Guesthouse 15 Minute Walk to Downtown Entertainment

Midtown Guesthouse 15 Minute Walk to Downtown Entertainment
Old Dauphin Way Historic District
9.6 out of 10, Exceptional, (8 reviews)
"It was just perfect for our little stay! Definitely recommend!"
United States
Rachel S.
$135 nightly
The price is $156
Sep 13 - Sep 14
Total with taxes and fees
Midtown Guesthouse 15 Minute Walk to Downtown Entertainment
A cruise ship deck with a large red funnel, a pool area, and a view of the city skyline in the background.

12. Small Studio Condo -Private balcony -Free Parking

Small Studio Condo -Private balcony -Free Parking
Old Dauphin Way Historic District
9.4 out of 10, Exceptional, (120 reviews)
"Host was super responsive, place was exactly as described. Great location, LOVED the balcony!"
United States
Rachel A.
$128 nightly
The price is $146
Sep 17 - Sep 18
Total with taxes and fees
Small Studio Condo -Private balcony -Free Parking
An outdoor seating area with two tables and four chairs, a vase with flowers, and a blue pole.

13. Stay minutes from USA with room for everyone to settle in. Enjoy spacious bedrooms, comfortable beds, a quiet setting, easy access to restaurants and groceries, plus a fully fenced yard for your dogs.

Stay minutes from USA with room for everyone to settle in. Enjoy spacious bedrooms, comfortable beds, a quiet setting, easy access to restaurants and groceries, plus a fully fenced yard for your dogs.
Mobile
10.0 out of 10, Exceptional, (2 reviews)
" Great location "
United States
Edwin G.
$311 nightly
The price is $350
Oct 12 - Oct 13
Total with taxes and fees
Stay minutes from USA with room for everyone to settle in. Enjoy spacious bedrooms, comfortable beds, a quiet setting, easy access to restaurants and groceries, plus a fully fenced yard for your dogs.
A bathroom with a white sink, a mirror, and a door.

14. King Bed |OYO Hotel Mobile

King Bed |OYO Hotel Mobile
Llanfair
10.0 out of 10, Exceptional, (74 reviews)
"Everything was spacious enough for us, great location near shopping too."
United States
Anonymous traveler
$63 nightly
The price is $70
Sep 30 - Oct 1
Total with taxes and fees
King Bed |OYO Hotel Mobile
An outdoor seating area with two tables and four chairs, a vase with flowers, and a blue pole.

15. Cozy 2BR Retreat | Close to Top Mobile Attractions

Cozy 2BR Retreat | Close to Top Mobile Attractions
Mobile
7.8 out of 10, Good, (7 reviews)
"Great place central to area of Univ South Alabama All amenities where available Comfortable place So if of stay in the place again"
United States
Eduardo M.
$292 nightly
The price is $328
Sep 13 - Sep 14
Total with taxes and fees
Cozy 2BR Retreat | Close to Top Mobile Attractions
A neatly made bed with white linens and a black metal frame, set against a backdrop of white curtains and blinds, with a lamp on the nightstand.

16. Quiet Midtown Studio w/Private Entrance

Quiet Midtown Studio w/Private Entrance
Old Dauphin Way Historic District
9.8 out of 10, Exceptional, (16 reviews)
"Nice and cozy. Perfect for a quick overnight stay!"
United States
Dan B.
Quiet Midtown Studio w/Private Entrance
A bedroom with a bed, two bedside tables, and wall art.

17. Cozy Midtown Mobile Home; Fireplace & Pet-Friendly

Cozy Midtown Mobile Home; Fireplace & Pet-Friendly
Dauphin Acres
10.0 out of 10, Exceptional, (1 review)
"We had an excellent stay and loved our space!"
United States
Barbara C.
$173 nightly
The price is $197
Oct 5 - Oct 6
Total with taxes and fees
Cozy Midtown Mobile Home; Fireplace & Pet-Friendly
A modern living room with a white sofa, two white armchairs, a wooden coffee table, and a potted plant.

18. Convenient 2BR Escape | Easy Walk to MOB

Convenient 2BR Escape | Easy Walk to MOB
Mobile
$308 nightly
The price is $346
Oct 5 - Oct 6
Total with taxes and fees
Convenient 2BR Escape | Easy Walk to MOB
A hotel room with two beds, a nightstand with a lamp, and a heater.

19. 2 Full Beds|Mobile AL

2 Full Beds|Mobile AL
Llanfair
10.0 out of 10, Exceptional, (116 reviews)
"Great location close to everything."
United States
Anonymous traveler
$68 nightly
The price is $76
Sep 30 - Oct 1
Total with taxes and fees
2 Full Beds|Mobile AL
An outdoor patio with a wooden pergola, string lights, a sofa, and wicker furniture.

20. Charming 3-bedroom house with AC, WiFi Mobile

Charming 3-bedroom house with AC, WiFi Mobile
Mobile
9.4 out of 10, Exceptional, (3 reviews)
"It was good and calm "
United States
Erica M.
$482 nightly
The price is $550
Sep 27 - Sep 28
Total with taxes and fees
Charming 3-bedroom house with AC, WiFi Mobile
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Semmes Hotel Reviews

Courtyard by Marriott Mobile Daphne/Eastern Shore

Courtyard by Marriott Mobile Daphne/Eastern Shore

10/10 Excellent
"It was a very comfortable stay."
Byron 1-night trip
Posted 1 hour ago
Courtyard by Marriott Mobile Daphne/Eastern Shore

Find out more about Semmes

Everything you need to know about Semmes vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Semmes vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Semmes vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Semmes vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Semmes. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Semmes in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $146 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Semmes rentals

At Expedia, we put the best Semmes vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Semmes rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Semmes vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Semmes. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Semmes?

Yes, we offer vacation rentals close to popular sights in Semmes, or you can go with a more secluded option if you'd like a relaxing place to stay. Semmes is known for its shopping and restaurants.

What's the top vacation rental that Semmes has to offer?

Midcentury Modern -Hot Tub - Retro Retreat: This vacation home rental outside of Semmes offers a balcony, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the hot tub in this rental home to help you unwind.

How many vacation rentals are there in Semmes?

Choose from 6 Expedia vacation rentals in Semmes for a memorable vacation.

What’s there to see and do in Semmes?

While exploring the area, visit family-friendly sights like Gulf Coast Exploreum, or get outside and enjoy nature at Bienville Square. Other places in town to visit include Semmes City Hall and Semmes Library.

What’s a vacation rental in Semmes like?

Vacation rentals are privately owned properties where you can stay for short or long periods in Semmes. Vacation rentals offer amenities like WiFi and washers and dryers so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, vacation rentals can provide a sense of seclusion away from shared hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a great choice for a small group gathering.