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Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21
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Jan 2 - Jan 4
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Jan 30 - Feb 1

Guest Houses in Seneca

No exact matches found, but these alternatives could be just right

Recommended hotels in Seneca

Aerial view
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 star property
Seneca
9.0 out of 10, Wonderful, (1009)
"Overall great stay."
United States
Daniel
$123 nightly
The price is $135
Dec 4 - Dec 5
Total with taxes and fees
Lakeside Lodge Clemson
Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 star property
Downtown
8.0 out of 10, Very Good, (664)
"Friendly check in, clean room."
United States
connie
$79 nightly
The price is $87
Dec 14 - Dec 15
Total with taxes and fees
Quality Inn Seneca Clemson Area US-123
Lobby
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 star property
Seneca
8.4 out of 10, Very Good, (637)
"The stay was amazing "
United States
Tabatha
$89 nightly
The price is $98
Dec 21 - Dec 22
Total with taxes and fees
Best Western Seneca-Clemson
Lobby
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 star property
Seneca
9.2 out of 10, Wonderful, (788)
"Staff was very friendly. Everything was very clean. Very quite in room"
United States
Dianna
$95 nightly
The price is $105
Dec 12 - Dec 13
Total with taxes and fees
Tru by Hilton Seneca Clemson
Exterior
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
Seneca
9.2 out of 10, Wonderful, (660)
"Great place to stay"
United States
Jose
$103 nightly
The price is $114
Dec 14 - Dec 15
Total with taxes and fees
Hampton Inn & Suites Seneca-Clemson Area
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2.0 star property
Seneca
9.8 out of 10, Exceptional, (49)
"The place was absolutely magnificent."
United States
David
$116 nightly
The price is $127
Dec 8 - Dec 9
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
"Nice hotel by the lake"
United States
Mike
$120 nightly
The price is $132
Dec 7 - Dec 8
Total with taxes and fees
Fairfield Inn & Suites Seneca Clemson Univ Area
Property grounds
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC

Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC

Seneca
10.0 out of 10, Exceptional, (12)
"Great hidden gem in Seneca for a Clemson football weekend. Property was amazing, loved the animals…..we will be back! "
United States
Allison H.
$189 nightly
The price is $208
Dec 4 - Dec 5
Total with taxes and fees
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
Fridge, microwave, oven, stovetop
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Seneca
10.0 out of 10, Exceptional, (12)
"Very nice, great surroundings. Everyone was nice and pleasant to meet while there. Great place to stay for Clemson games!!! "
United States
Glenda
$183 nightly
The price is $201
Dec 8 - Dec 9
Total with taxes and fees
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Smart TV, fireplace
Enjoy one of our RV units son less of a headache for you this vacation!

Enjoy one of our RV units son less of a headache for you this vacation!

Seneca
7.0 out of 10, Good, (2)
"Very nice camper in a good location close to Clemson. Perfect for attending games. Took us 10-15 minites to get to stadium. All on back roads.Host was responsive to messages and requests. Only thing I would recommend to host is to reach out a couple days before just to give you check in details. Check in was very simple, but i had to reach to them to get the details. Would definitely stay here again!!"
United States
Hunter P.
$139 nightly
The price is $153
Dec 9 - Dec 10
Total with taxes and fees
Enjoy one of our RV units son less of a headache for you this vacation!
Fridge, microwave, oven, stovetop
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

2.0 star property
Downtown
10.0 out of 10, Exceptional, (16)
"The owner, John, is an exceptional host and made our stay even more enjoyable. The location is so convenient to Downtown Seneca restaurants and grocers. We would recommend this home as a fair value. "
United States
Joann H.
$293 nightly
The price is $318
Dec 4 - Dec 5
Total with taxes and fees
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Fridge, microwave, oven, stovetop
Tucker Farm Cottage on Century Farm

Tucker Farm Cottage on Century Farm

Seneca
10.0 out of 10, Exceptional, (31)
"Excellent stay, beautiful area!"
United States
Barbara W.
$360 nightly
The price is $385
Dec 4 - Dec 5
Total with taxes and fees
Tucker Farm Cottage on Century Farm
Property grounds
Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin

2.0 star property
Seneca
$172 nightly
The price is $189
Dec 4 - Dec 5
Total with taxes and fees
Cozy Clemson TIny House Cabin
Room, 1 King Bed, Non Smoking | Desk, free cribs/infant beds, rollaway beds, free WiFi
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
Seneca
6.8 out of 10, (718)
"The rooms have been renovated it was nice and clean especially for the price. "
United States
Sherri
$67 nightly
The price is $74
Dec 7 - Dec 8
Total with taxes and fees
Days Inn by Wyndham Seneca / Clemson Area
Private kitchen
The Clemson Cottage - 3.6 mi. to Memorial Stadium

The Clemson Cottage - 3.6 mi. to Memorial Stadium

Seneca
10.0 out of 10, Exceptional, (12)
"Adorable and clean home convenient to Clemson’s campus. We enjoyed our stay and Tyler was an exceptional host! "
United States
Mandy H.
$359 nightly
The price is $395
Dec 16 - Dec 17
Total with taxes and fees
The Clemson Cottage - 3.6 mi. to Memorial Stadium
Property grounds
3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

Seneca
10.0 out of 10, Exceptional, (4)
"Great place with a lot close by"
United States
Aldor D.
$247 nightly
The price is $271
Dec 12 - Dec 13
Total with taxes and fees
3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Microwave, oven, stovetop, dishwasher
The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson

Seneca
10.0 out of 10, Exceptional, (2)
"Absolutely! Perfect space for our needs, so for accommodating for our family & pet. "
United States
Gennifer Q.
$513 nightly
The price is $557
Dec 4 - Dec 5
Total with taxes and fees
The Big Golf House- 10 miles to Clemson
Fridge, microwave, oven, stovetop
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

Serenity Bay
9.8 out of 10, Exceptional, (129)
"A wonderful stay! The house offered many different spaces and the lake access/dock was perfect!!"
United States
stacy s.
$566 nightly
The price is $623
Dec 4 - Dec 5
Total with taxes and fees
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger
Fridge, microwave, oven, stovetop
Johnsons Cove - Lakefront Retreat With EV Charger

Johnsons Cove - Lakefront Retreat With EV Charger

Seneca
10.0 out of 10, Exceptional, (1)
"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."
United States
Rebecca G.
$749 nightly
The price is $795
Dec 7 - Dec 8
Total with taxes and fees
Johnsons Cove - Lakefront Retreat With EV Charger
Terrace/patio
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Seneca
6.0 out of 10, (1)
"The tiny house was clean, well-appointed, and sits on a nice setting. The host responded late on Sat, to a problem from the previous guests, so we appreciated that.Must mention that the loft bedroom is not practical for an adult since you cannot stand/no storage. Yes, there is a water/lake view, but since the dock is 1/2 out of the water, it is more like a stream."
United States
Gary S.
$233 nightly
The price is $256
Dec 4 - Dec 5
Total with taxes and fees
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Best Western Seneca-Clemson

Best Western Seneca-Clemson

10/10 Excellent
"Love this place! The front desk crew are the best!"
Jerry 3-night trip
Posted 3 days ago
Best Western Seneca-Clemson

Find out more about Seneca

Seneca Guest Houses information

Number of reviews
4,934
Accommodation
3 Guest Houses
Lowest Price
$74
Highest Price
$795

Frequently asked questions

What is the nightly rate for a guest house in Seneca?
Rates for Seneca guest houses vary, but travelers can find great-value prices from $74 with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Seneca guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.
What's the difference between a Seneca guest house and a B&B?
A guest house in Seneca is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.

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