
Seneca Vacations from $501
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The Latest Seneca vacation packages
Price found within the past 48 hours. Click for updated prices.

Comfort Inn & Suites Greer - Greenville
Price was $625, price is now $501 per person
$501
per person
May 21 - May 25
found 1 hour ago
Roundtrip non-stop flight included
Baltimore (BWI) to Greenville (GSP)
8.6/10 Excellent! (711 reviews)
Perfect in every aspect. Really wonderfull staff.
Reviewed on Feb 18, 2026

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
Save 100% on your flight
Price was $1,440, price is now $1,125 per person
$1,125
per person
May 21 - May 25
found 1 hour ago
Roundtrip non-stop flight included
Baltimore (BWI) to Greenville (GSP)
9.6/10 Exceptional! (406 reviews)
The room was wonderful. The view amazing. The staff efficient and courteous. Loved the artwork throughout the hotel!
Reviewed on Feb 24, 2026


Hilton Greenville
Price was $661, price is now $531 per person
$531
per person
May 21 - May 25
found 1 hour ago
Roundtrip non-stop flight included
Baltimore (BWI) to Greenville (GSP)
8.2/10 Very Good! (1,004 reviews)
The room was exceptionally clean. We particularly appreciated the services of a refreshed room daily. The staff was extremely friendly, helpful, and courteous. We plan to make this hotel our choice whenever we visit Greenville in the future.
The Stewarts
Reviewed on Feb 22, 2026

Where to stay in Seneca
Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca

Serenity Bay
Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
Seneca Hotel Deals

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Feb 26 to Feb 27
$135 total
Feb 26 - Feb 27
Total with taxes and fees
9/10 Wonderful! (1,008 reviews)
Clean room, great service!
Reviewed on Feb 23, 2026

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Mar 5 to Mar 6
$92 total
Mar 5 - Mar 6
Total with taxes and fees
8/10 Very Good! (681 reviews)
All great
Reviewed on Feb 21, 2026

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street Seneca SC
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $132 total per night from Mar 1 to Mar 2
$132 total
Mar 1 - Mar 2
Total with taxes and fees
9.2/10 Wonderful! (682 reviews)
Great having a washer and dry available and the breakfast staff was amazing and very nice.
Reviewed on Feb 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Seneca Vacation Packages
Seneca Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Population | 8,300 |
Max Temp Winter | 50ºF |
Max Temp Summer | 90ºF |
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.






















