Seneca Vacations from $364

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The Latest Seneca vacation packages

Price found within the past 48 hours. Click for updated prices.
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
Price was $452, price is now $364 per person
$364
per person
Dec 28 - Jan 1
found 20 hours ago
Roundtrip flight included
Orlando (MCO) to Greenville (GSP)
17.2/10 Exceptional! (1,001 reviews)
Parking was fine. Did not eat breakfast.

Reviewed on Nov 12, 2025

Hotel Hartness

Hotel Hartness

4 out of 5
Price was $751, price is now $566 per person
$566
per person
Dec 28 - Jan 1
found 20 hours ago
Roundtrip flight included
Orlando (MCO) to Greenville (GSP)
9.8/10 Exceptional! (601 reviews)
Excellent staff and facilities. Very clean, comfortable and welcoming atmosphere and very enjoyable stay

Reviewed on Nov 13, 2025

Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hampton Inn & Suites Greenville-Downtown-RiverPlace

2.5 out of 5
Greenville Downtown
Save 100% on your flight
Price was $871, price is now $673 per person
$673
per person
Dec 25 - Jan 1
found 13 hours ago
Roundtrip flight included
Orlando (MCO) to Greenville (GSP)
18.8/10 Exceptional! (1,007 reviews)
Really nice and well kept

Reviewed on Nov 15, 2025

Best Western Plus Spartanburg

Best Western Plus Spartanburg

2.5 out of 5
Price was $535, price is now $417 per person
$417
per person
Dec 25 - Jan 1
found 13 hours ago
Roundtrip flight included
Orlando (MCO) to Greenville (GSP)
8.4/10 Very Good! (1,006 reviews)
The room faced the interstate, so it was very noisy. The curtains were sheer. There were food crumbs under the nightstand. Staff was friendly. The breakfast was fresh, with a few options.

Reviewed on Nov 3, 2025

Hilton Greenville

Hilton Greenville

3.5 out of 5
Price was $468, price is now $375 per person
$375
per person
Dec 28 - Jan 1
found 20 hours ago
Roundtrip flight included
Orlando (MCO) to Greenville (GSP)
16.4/10 Exceptional! (1,009 reviews)
The room was not as clean as it should have been. The lobby was beautiful. My room was on the 4th floor. As soon as i stepped off of the elevator, there was a sour, musty smell. The room didn’t smell that way but it seemed at times, there would be a whiff of it. There was hair on my pillow and the bathroom floor was dirty. Hair was there too. It was a different texture than mine, so I know i didn't bring it in. I only stayed one night and got there late. I wouldn't stay again. The front desk workers were ok. Not rude, but didn’t seem to really care if I was there or not. Ok experience.

Reviewed on Nov 9, 2025

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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca
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Downtown

3 out of top 10 points of interest in this area

While visiting Downtown, you might make a stop by sights like Seneca Historic District and Oconee County Library Seneca Branch.

Find hotels in Downtown

Seneca Hotel Deals

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $89 total per night from Dec 7 to Dec 8
$89 total
Dec 7 - Dec 8
Total with taxes and fees
7.8/10 Good! (658 reviews)
Yes

Reviewed on Nov 14, 2025

Quality Inn Seneca Clemson Area US-123
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Nov 17 to Nov 18
$135 total
Nov 17 - Nov 18
Total with taxes and fees
9/10 Wonderful! (1,003 reviews)
Pretty solid

Reviewed on Nov 11, 2025

Lakeside Lodge Clemson
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd Seneca SC
$76 nightly
The price is $83 total per night from Nov 19 to Nov 20
$83 total
Nov 19 - Nov 20
Total with taxes and fees
6.8/10 (714 reviews)
Clean, friendly.. great service and lots to do

Reviewed on Oct 28, 2025

Days Inn by Wyndham Seneca / Clemson Area
See all 1,628 properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Seneca Vacation Packages

Seneca Essential Information

Language
English
Currency
U.S dollars
Population
8,300
Max Temp Winter
50ºF
Max Temp Summer
90ºF

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Frequently asked questions

How much does a Seneca vacation package cost?
You'll find cheap prices from $364 on Expedia for your Seneca break. However, factors like the season, choice of hotel and length of stay will determine how much your vacation to Seneca costs.
What are the cheapest months to go to Seneca?
You can typically find lower rates and better availability in September, October and December. Browse our cheap Seneca vacation packages and you could land some great off-season discounts.
How many days is enough for Seneca?
Usually, a handful of days is enough to tick off the top attractions during your Seneca vacation. But if you prefer to have more time to rest or go on day tours, consider extending your itinerary.
How to find the best Seneca package deals?
Start your search for a Seneca package deal by entering your destination and travel dates under our "Packages" tab. Then add some filters, like "Guest rating" and "Property type," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the perfect Seneca package deal right away, simply tweak your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Seneca escape underway.
Is it cheaper to book a Seneca vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, car rental and flight into one great-value price and you could save hundreds of dollars. You'll generally get a better deal than booking each component separately. And you'll still enjoy the freedom to create a personalized Seneca vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Seneca?
If you've got your Seneca travel dates locked in, book as early as you can to grab some fantastic deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment getaways? Our last-minute deals are great for traveling on a whim.
Does Expedia offer Book Now, Pay Later Seneca vacation packages?
Set off on your perfect escape to Seneca with help from our Book Now, Pay Later vacations. There's no need to scrimp and save or wait until your next payday — we've joined forces with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans allow you to spread the total cost over 3, 6 or 12 months. With no hidden charges or late payment fees, you can easily stay on budget and snap up cheap deals before they disappear.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.