
Seneca Vacations from $374
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The Latest Seneca vacation packages
Price found within the past 48 hours. Click for updated prices.

Comfort Inn & Suites Greer - Greenville
Price was $482, price is now $374 per person
$374
per person
Apr 28 - May 2
found 1 day ago
Roundtrip flight included
Washington (WAS) to Greenville (GSP)
8.6/10 Excellent! (764 reviews)
The room was clean and seemed new. Breakfast was very good with something for everyone. Parking was right in front of the door and was well-lit. The staff was pleasant, and it was a very nice stay. I would stay there again.
Reviewed on Mar 5, 2026




Where to stay in Seneca
Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca

Serenity Bay
Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
Seneca Hotel Deals

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Mar 8 to Mar 9
$135 total
Mar 8 - Mar 9
Total with taxes and fees
9/10 Wonderful! (1,004 reviews)
I got a great corner room this time. Just wish the hottub was open at night. Very weird that it's not.
Reviewed on Mar 5, 2026

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
$109 nightly
The price is $120 total per night from Mar 9 to Mar 10
$120 total
Mar 9 - Mar 10
Total with taxes and fees
9.8/10 Exceptional! (65 reviews)
Very nice and quaint
Reviewed on Mar 7, 2026

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street Seneca SC
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $135 total per night from Mar 15 to Mar 16
$135 total
Mar 15 - Mar 16
Total with taxes and fees
9.2/10 Wonderful! (684 reviews)
Clean
Reviewed on Mar 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Seneca Vacation Packages
Seneca Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Population | 8,300 |
Max Temp Winter | 50ºF |
Max Temp Summer | 90ºF |
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