Seneca Vacations from $661

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The Latest Seneca vacation packages

Price found within the past 48 hours. Click for updated prices.
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
Price was $825, price is now $661 per person
$661
per person
Oct 12 - Oct 19
found 1 day ago
Roundtrip flight included
Boston (BOS) to Greenville (GSP)
8.6/10 Excellent! (1,005 reviews)
The buffet breakfast was okay. We need breakfast to go to 10:30am. The rooms needs updating. Al well as the vending and ice machines. I had to travel to the bar for ice.

Reviewed on Jul 23, 2026

Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek

4 out of 5
Price was $1,136, price is now $865 per person
$865
per person
Oct 12 - Oct 19
found 1 day ago
Roundtrip flight included
Boston (BOS) to Greenville (GSP)
9.6/10 Exceptional! (4 reviews)
Great space to rent versus have a hotel room. The unit was very spacious, clean and comfortable. Our only issue was getting an immediate response with an issue discovered at check in. Because Landing had to contact the onsite office for the apartments, we did not receive the pool pass until half way through our visit. It was very disappointing not to be able to use the pool the first two days since we intentionally booked this place for the pool.

Reviewed on Jul 23, 2026

Hilton Greenville

Hilton Greenville

3.5 out of 5
Price was $1,145, price is now $884 per person
$884
per person
Oct 12 - Oct 19
found 1 day ago
Roundtrip flight included
Boston (BOS) to Greenville (GSP)
8.4/10 Very Good! (1,019 reviews)
Hotel feels dated. Our room as smokey but they helped us change -- queen beds on the small side. Not the best area. But otherwise satisfactory.

Reviewed on Jul 25, 2026

Holiday Inn Greenville - Woodruff Road by IHG

Holiday Inn Greenville - Woodruff Road by IHG

3 out of 5
Price was $911, price is now $737 per person
$737
per person
Oct 12 - Oct 19
found 1 day ago
Roundtrip flight included
Boston (BOS) to Greenville (GSP)
8.6/10 Excellent! (703 reviews)

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
Greenville Downtown
Save 100% on your flight
Price was $2,549, price is now $2,082 per person
$2,082
per person
Oct 12 - Oct 19
found 1 day ago
Roundtrip flight included
Boston (BOS) to Greenville (GSP)
9.6/10 Exceptional! (527 reviews)
The room we had was generally clean although it appears that the carpet was not vacuumed. There were crumbs and pretzel remnants on the carpet- which we cleaned ourselves. Also had a scare from a spider on one of the chairs. The hotel itself was gorgeous with beautifully maintained grounds. The beds were super comfortable.

Reviewed on Jul 24, 2026

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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca
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Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Find hotels in Serenity Bay

Stay near popular Seneca attractions

A waterfall surrounded by autumn foliage.

High Falls County Park

Nestled along Lake Keowee with the Blue Ridge Mountains as backdrop, High Falls County Park offers pristine swimming and camping spots. Reserve waterfront campsites early to enjoy the park's serene natural setting.
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Seneca Hotel Deals

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Jul 26 to Jul 27
$135 total
Jul 26 - Jul 27
Total with taxes and fees
9/10 Wonderful! (1,007 reviews)
"The receptionist at the front desk was the rudest, most apathetic customer service representative I've ever had the misfortune of coming into contact with. Our room was not ready at check in, and in the end we left and booked with another hotel. I would 0/10 recommend this hotel. It was awful on ..."

Reviewed on Jul 24, 2026

Lakeside Lodge Clemson
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Fully refundable
$88 nightly
The price is $96 total per night from Jul 30 to Jul 31
$96 total
Jul 30 - Jul 31
Total with taxes and fees
Quality Inn Seneca Clemson Area US-123
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
$124 nightly
The price is $136 total per night from Aug 25 to Aug 26
$136 total
Aug 25 - Aug 26
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
See all 1,685 properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Seneca Vacation Packages

Seneca Essential Information

Language
English
Currency
U.S dollars
Population
8,300
Max Temp Winter
50ºF
Max Temp Summer
90ºF

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Frequently asked questions

How much does a Seneca vacation package cost?
You'll find cheap prices from $661 on Expedia for your Seneca break. However, factors like the season, choice of hotel and length of stay will determine how much your vacation to Seneca costs.
What are the cheapest months to go to Seneca?
You can typically find lower rates and better availability in September, October and December. Browse our cheap Seneca vacation packages and you could land some great off-season discounts.
How many days is enough for Seneca?
Usually, a handful of days is enough to tick off the top attractions during your Seneca vacation. But if you prefer to have more time to rest or go on day tours, consider extending your itinerary.
How to find the best Seneca package deals?
Start your search for a Seneca package deal by entering your destination and travel dates under our "Packages" tab. Then add some filters, like "Guest rating" and "Property type," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the perfect Seneca package deal right away, simply tweak your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Seneca escape underway.
Is it cheaper to book a Seneca vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, car rental and flight into one great-value price and you could save hundreds of dollars. You'll generally get a better deal than booking each component separately. And you'll still enjoy the freedom to create a personalized Seneca vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Seneca?
If you've got your Seneca travel dates locked in, book as early as you can to grab some fantastic deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment getaways? Our last-minute deals are great for traveling on a whim.
Does Expedia offer Book Now, Pay Later Seneca vacation packages?
Set off on your perfect escape to Seneca with help from our Book Now, Pay Later vacations. There's no need to scrimp and save or wait until your next payday — we've joined forces with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans allow you to spread the total cost over 3, 6 or 12 months. With no hidden charges or late payment fees, you can easily stay on budget and snap up cheap deals before they disappear.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.