St. Ann Vacations from $273

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your St. Ann Vacation

From its friendly locals to its laid-back lifestyle and beyond, there's much to like about St. Ann. Discover the wonders of this captivating city with a St. Ann vacation package that's customized for you. Ameristar Casino St. Charles, Hollywood Casino Amphitheatre and Historic Main Street are just a few of the many sights you'll want to explore during your trip to St. Ann. Check out Expedia's extensive range of travel options and begin planning your ultimate vacation to St. Ann today.

The Latest St. Ann vacation packages

Price found within the past 48 hours. Click for updated prices.
HoteLumiere at the Arch - A Caesars Rewards Destination

HoteLumiere at the Arch - A Caesars Rewards Destination

4 out of 5
Downtown St. Louis
Save 100% on your flight
Price was $389, price is now $273 per person
$273
per person
Jun 24 - Jun 27
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
6.8/10 (1,006 reviews)
Staff was generally unfriendly, odd smell about the place

Reviewed on Apr 12, 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $761, price is now $392 per person
$392
per person
Jun 24 - Jun 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,624 reviews)
Poor quality breakfast buffet, unsecured parking, worn furnishings, in need of a redo. Overpriced for conditions.

Reviewed on Apr 17, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $447, price is now $296 per person
$296
per person
Jun 24 - Jun 27
found 13 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,011 reviews)
The bar was the perfect spot for a nightcap! Breakfast was also good, though there wasn't much seating available.

Reviewed on Apr 18, 2026

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

4 out of 5
Downtown St. Louis
Save 100% on your flight
Price was $680, price is now $472 per person
$472
per person
Jun 24 - Jun 27
found 13 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,023 reviews)
This hotel had a very elegant modern vibe while encapsulating the big city bustle, it was very convenient to the stadiums, the arch and the river. The only downfall which is not their fault is the dilapidated hotel right across the street, definitely an eyesore but hopefully the city will have an amazing opportunity to revitalize that area! But back to this idea hotel, it was very clean and comfortable!

Reviewed on Apr 15, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Save 100% on your flight
Price was $529, price is now $375 per person
$375
per person
Jun 24 - Jun 27
found 13 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.4/10 Very Good! (1,000 reviews)
Enjoyed our stay. Clean facility

Reviewed on Apr 4, 2026

Don't see what you're looking for?
See all available trips from Columbus to St. Ann
View all trips

Discover the most popular places to visit in St. Ann

Busch Stadium

Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium
Union Station, St. Louis, MO

St. Louis Union Station

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

St. Louis Union Station
Gateway Arch

Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch

What to do in St. Ann

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis Walking Tour with St Louis Arch Ticket

St. Louis Walking Tour with St Louis Arch Ticket

$89
per adult
St. Louis Walking Tour with St Louis Arch Ticket
Best of St. Louis Small Group Tour w/ Arch & River Cruise

St. Louis Premium Small Group Tour With Arch & River Cruise

$169
per adult
84% of travellers recommend
St. Louis Premium Small Group Tour With Arch & River Cruise
See all activities in St. Ann

St. Ann Hotel Deals

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from May 3 to May 4
$106 total
May 3 - May 4
Total with taxes and fees
9.4/10 Exceptional! (2,942 reviews)
My friend and I stayed here for 4 days and 3 nights on a girls trip. The location was perfect, within a 10-20 minute drive of everywhere we wanted to go. We were able to check in a little early which was extremely convenient for us! We were also pleasantly surprised by the hotel doing a complimentary ...

Reviewed on Apr 18, 2026

Pear Tree Inn St. Louis Airport
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

2.5 out of 5
10820 Pear Tree Lane St. Ann MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $147 total per night from May 4 to May 5
$147 total
May 4 - May 5
Total with taxes and fees
9.2/10 Wonderful! (1,591 reviews)
Staff is always so friendly!! Would definitely stay here again. Room was super clean and breakfast was great, also!

Reviewed on Apr 17, 2026

Wingate by Wyndham St. Louis Airport
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $111 total per night from Apr 19 to Apr 20
$111 total
Apr 19 - Apr 20
Total with taxes and fees
9/10 Wonderful! (3,155 reviews)
Front desk is extremely slow.

Reviewed on Apr 18, 2026

Clayton Plaza Hotel & Extended Stay
See all 1,941 properties in St. Ann
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best St. Ann Vacation Packages

St. Ann Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)
Population
13,000
Max Temp Winter
40ºF
Max Temp Summer
85ºF
Top Sights
St. Louis Zoo, Fox Theater and Magic House - St. Louis Childrens Museum

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a St. Ann vacation package cost?
You'll find cheap prices from $273 on Expedia for your St. Ann escape. However, factors like the length of stay, hotel choice and season will influence how much your vacation to St. Ann costs.
What are the cheapest months to go to St. Ann?
If you'd like to book a cheap St. Ann vacation package, consider planning a trip in November, December and January. You'll typically find better prices on airfares and hotels during these quieter months — perfect for travelers wishing to save money.
How many days is enough for St. Ann?
The ideal duration for your St. Ann vacation depends on what you'd like to do. Typically, a handful of days to a week will give you plenty of time to tick off all the leading attractions and discover some hidden spots along the way.
How to find the best St. Ann package deals?
Use Expedia's filters to find some terrific St. Ann package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or search for St. Ann package deals in the off-season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to lock in your vacation package well in advance.
Is it cheaper to book a St. Ann vacation as a package?
You can enjoy significant savings on your St. Ann getaway by booking a tailored vacation package. Check the "Package" heading, then enter your destination and travel dates to view some great flight and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to St. Ann?
If you've got your St. Ann vacation dates finalized, book as early as you can to bag some unbeatable deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spontaneous adventures? Our last-minute deals are great for setting off on a whim.
How to plan a trip to St. Ann?

  1. Choose your travel dates: What you plan to do in St. Ann and your preferred season can help you decide when to go.
  2. Set your budget: Consider costs such as transportation, flights and meals when calculating how much to save for your trip to St. Ann. Then, choose a property that fits your budget, whether that's an economical stay or a lavish getaway.
  3. Discover St. Ann with our trip planning tool: Gain insights into the top attractions and best stays for your trip to St. Ann. You can also save your favorite places, collaborate with your group and arrange all your plans in one place.
  4. Decide how long to go away for: Now that you're more familiar with St. Ann, you can figure out the perfect length of your vacation. Pull together a rough itinerary and give yourself enough time to cover everything you want to see.
  5. Combine your hotel and flights: Epic destination, check. Length of stay, check. Now all that's left is to pick a St. Ann vacation package that brings all your bookings together.
  6. Add on experiences and excursions: Read our dedicated travel guide to find some awesome things to do in St. Ann. Book tickets or make reservations before you go to save time and avoid the hassle of searching for activities once you arrive.

Does Expedia offer Book Now, Pay Later St. Ann vacation packages?
Secure your perfect trip to St. Ann with our Book Now, Pay Later vacations. No need to scrimp and save or wait until your next paycheck — we've joined forces with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans let you split the cost over 3, 6 or 12 months. With no late payment fees or extra charges, it's easy to stay on budget and snap up cheap deals before they disappear.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.