$317 Cheap American Airlines flights Cozumel (CZM) to Chicago (ORD)

Scoring cheap one-way American Airlines flights from CZM to ORD from $317 on Expedia is easy — just filter by "Price (lowest to highest)." Or check out our affordable return fares from $483 for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Scoring the best American Airlines deals from CZM to ORD often comes down to timing. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. As an added bonus, you can pocket 17% on average by buying your tickets on a Sunday compared to a Friday, which is usually the most expensive day to book.* It's a good idea to start checking out flights about one month before you plan to travel.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The earliest American Airlines flight from CZM to ORD departs at 4:10PM UTC-5, arriving at 7:10PM UTC-6. If you want to jet off later in the day, the last American Airlines flight leaves CZM at 4:10PM UTC-5 and lands at ORD at 7:10PM UTC-6. Flying earlier is often a good option as morning flights are less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.