$149 Cheap American Airlines flights Des Moines (DSM) to Orange County (SNA)

Use the "Price (lowest to highest)" filter on Expedia to look for cheap American Airlines return flights from $273 from DSM to SNA. Affordable one-way fares from $149 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find cheap American Airlines fares from Des Moines Intl. Airport (DSM) to John Wayne Airport (SNA), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact the price you pay. Sunday is generally the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by choosing to book on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from DSM to SNA with American Airlines, filter your results by "Morning" and "Early Morning." Choosing an early flight generally means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.