Photo by Sig

Popular airlines from San Francisco to Santa Cruz Island
Avianca
LATAM Airlines Group
- Plan, book, fly with confidence
trending down icon Be in the knowGet alerts if flight prices drop or rise*bex rewards loyalty icon Book smarterSave up to 30% on select hotels after you book a flight*one key icon
Cheap Flights from San Francisco to Santa Cruz Island (SJC-GPS)
Prices were available within the past 7 days and start at $311 for one-way flights and $730 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 9 - Tue, Sep 16
SFO
San Francisco
GPS
Santa Cruz Island
$730 Roundtrip, found 1 day ago
$730
Roundtrip
found 1 day ago

Thu, Nov 6 - Thu, Nov 20
SFO
San Francisco
GPS
Santa Cruz Island
$741 Roundtrip, found 3 days ago
$741
Roundtrip
found 3 days ago

Tue, Sep 9 - Wed, Sep 24
SFO
San Francisco
GPS
Santa Cruz Island
$750 Roundtrip, found 1 day ago
$750
Roundtrip
found 1 day ago

Mon, Sep 8 - Thu, Sep 11
SFO
San Francisco
GPS
Santa Cruz Island
$751 Roundtrip, found 2 hours ago
$751
Roundtrip
found 2 hours ago

Sun, Jan 18 - Fri, Jan 30
SFO
San Francisco
GPS
Santa Cruz Island
$975 Roundtrip, found 6 days ago
$975
Roundtrip
found 6 days ago

Wed, Aug 13 - Sat, Aug 23
SFO
San Francisco
GPS
Santa Cruz Island
$992 Roundtrip, found 13 hours ago
$992
Roundtrip
found 13 hours ago
Alternative airports
Prices were available within the past 7 days. Prices and availability are subject to change.
Explore a world of travel with Expedia
- Bellavista Hotels
- B&B in Bellavista
- Galápagos Hotels
- Resorts & Hotels with Spas in Galápagos
- Honeymoon Resorts & in Galápagos
- Family Hotels in Galápagos
- Hotel Wedding Venues Hotels in Galápagos
- Luxury Hotels in Galápagos
- Hostels in Galápagos
- Hotels with Tennis Courts in Galápagos
- Villas in Galápagos
- Beach Hotels in Galápagos
- Apartments in Galápagos
- Green Hotels in Galápagos
- Vacation Homes in Galápagos
- Historic Hotels in Galápagos
- Cheap Hotels in Galápagos
- Hotels with Suites in Galápagos
- Romantic Hotels in Galápagos
- Oceanfront Hotels in Galápagos
- Pet-friendly Hotels in Galápagos
- Guest Houses in Galápagos
- Hotels with a View in Galápagos
- Hotels with Free Breakfast in Galápagos
- Hotels with a Gym in Galápagos
- B&B in Galápagos
- Lodges in Galápagos
- Hotels with Air Conditioning in Galápagos
- Cabin Rentals in Galápagos
- Boutique Hotels in Galápagos
- Hotels with an Outdoor Pool in Galápagos
- Santa Rosa Hotels
- 4 Star Hotels in Santa Rosa
- Puerto Ayora Hotels
- Hotels with Tennis Courts in Puerto Ayora
- Hotels with Free Airport Shuttle in Puerto Ayora
- Hotels with Laundry Facilities in Puerto Ayora
- Hotels with Restaurants in Puerto Ayora
- Apartments in Puerto Ayora
- B&B in Puerto Ayora
- Cheap Hotels in Puerto Ayora
- Luxury Hotels in Puerto Ayora
- Beach Hotels in Puerto Ayora
- Hostels in Puerto Ayora
- Oceanfront Hotels in Puerto Ayora
- Hotels with a Gym in Puerto Ayora
- Honeymoon Resorts & in Puerto Ayora
- Lodges in Puerto Ayora
- Gay friendly Hotels in Puerto Ayora
- Hotels with a Pool in Puerto Ayora
- Hotel with a Concierge Hotels in Puerto Ayora
- Romantic Hotels in Puerto Ayora
- Hotels with Childcare in Puerto Ayora
- Hotels near Charles Darwin Research Station
- Hotels near Malecon
- Hotels near Academy Bay
- Hotels near Playa de los Alemanes
- Hotels near Las Grietas
- El Cascajo Hotels
- Hotels near El Garrapatero Beach
- Hotels near South Plaza Island
- Visit Bellavista
- Bellavista Vacations
- Galápagos Vacations
- All inclusive Vacation Packages Galápagos
- Visit Galápagos
- Luxury Vacation Packages Galápagos
- Visit Santa Rosa
- Santa Rosa Vacations
- Rancho Primicias
- Visit Puerto Ayora
- Puerto Ayora Vacations
- Charles Darwin Research Station
- Malecon
- Academy Bay
- Playa de los Alemanes
- Las Grietas
- Tortuga Bay Beach
- Visit El Cascajo
- El Cascajo Vacations
- El Garrapatero Beach
*Available to One Key members.