$22 Cheap Flights from Antofagasta (ANF) to Santiago (SCL)

View $22 flight on Tue, Sep 30, 2025Opens in a new window

Popular airlines from Antofagasta (ANF-Cerro Moreno Intl.) to Santiago Intl. Airport (SCL)

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Cheap Flights from Antofagasta to Santiago (ANF-SCL)

Prices were available within the past 7 days and start at $22 for one-way flights and $44 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

SKY AIRLINE
Sun, Aug 31 - Tue, Sep 2
ANF
Antofagasta
SCL
Santiago
$44 Roundtrip, found 13 hours ago
$44
Roundtrip
found 13 hours ago
Select SKY AIRLINE flight, departing Sun, Aug 31 from Antofagasta to Santiago, returning Tue, Sep 2, priced at $44 found 13 hours ago
SKY AIRLINE
Fri, Oct 17 - Sun, Oct 19
ANF
Antofagasta
SCL
Santiago
$65 Roundtrip, just found
$65
Roundtrip
just found
Select SKY AIRLINE flight, departing Fri, Oct 17 from Antofagasta to Santiago, returning Sun, Oct 19, priced at $65 just found
SKY AIRLINE
Sun, Aug 31 - Tue, Sep 2
ANF
Antofagasta
SCL
Santiago
$72 Roundtrip, found 13 hours ago
$72
Roundtrip
found 13 hours ago
Select SKY AIRLINE flight, departing Sun, Aug 31 from Antofagasta to Santiago, returning Tue, Sep 2, priced at $72 found 13 hours ago
Jetsmart SPA
Fri, Oct 17 - Sun, Oct 19
ANF
Antofagasta
SCL
Santiago
$75 Roundtrip, just found
$75
Roundtrip
just found
Select Jetsmart SPA flight, departing Fri, Oct 17 from Antofagasta to Santiago, returning Sun, Oct 19, priced at $75 just found
Jetsmart SPA
Sun, Aug 31 - Tue, Sep 2
ANF
Antofagasta
SCL
Santiago
$76 Roundtrip, found 13 hours ago
$76
Roundtrip
found 13 hours ago
Select Jetsmart SPA flight, departing Sun, Aug 31 from Antofagasta to Santiago, returning Tue, Sep 2, priced at $76 found 13 hours ago
SKY AIRLINE
Sun, Aug 31 - Tue, Sep 2
ANF
Antofagasta
SCL
Santiago
$78 Roundtrip, found 13 hours ago
$78
Roundtrip
found 13 hours ago
Select SKY AIRLINE flight, departing Sun, Aug 31 from Antofagasta to Santiago, returning Tue, Sep 2, priced at $78 found 13 hours ago
SKY AIRLINE
Wed, Sep 24 - Tue, Sep 30
ANF
Antofagasta
SCL
Santiago
$78 Roundtrip, found 5 days ago
$78
Roundtrip
found 5 days ago
Select SKY AIRLINE flight, departing Wed, Sep 24 from Antofagasta to Santiago, returning Tue, Sep 30, priced at $78 found 5 days ago
SKY AIRLINE
Fri, Nov 14 - Sun, Nov 16
ANF
Antofagasta
SCL
Santiago
$80 Roundtrip, found 3 days ago
$80
Roundtrip
found 3 days ago
Select SKY AIRLINE flight, departing Fri, Nov 14 from Antofagasta to Santiago, returning Sun, Nov 16, priced at $80 found 3 days ago
SKY AIRLINE
Fri, Oct 17 - Sun, Oct 19
ANF
Antofagasta
SCL
Santiago
$80 Roundtrip, just found
$80
Roundtrip
just found
Select SKY AIRLINE flight, departing Fri, Oct 17 from Antofagasta to Santiago, returning Sun, Oct 19, priced at $80 just found
LATAM Airlines Group
Fri, Oct 17 - Sun, Oct 19
ANF
Antofagasta
SCL
Santiago
$84 Roundtrip, just found
$84
Roundtrip
just found
Select LATAM Airlines Group flight, departing Fri, Oct 17 from Antofagasta to Santiago, returning Sun, Oct 19, priced at $84 just found

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $93
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $93
Flights from Antofagasta (ANF) to Santiago (SCL)
Origin airport
Cerro Moreno Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Jetsmart SPA, LATAM Airlines Group, SKY AIRLINE
Roundtrip price
$43
Distance
687 mi
Average flight time
1 hour 52 mins

Antofagasta to Santiago Flights

The cheapest times to fly from Antofagasta to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Antofagasta to Santiago are during the month of August. You can find some of the cheapest flights from Antofagasta to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Antofagasta to Santiago

Sunday is one of the best days to book for cheap flights from Antofagasta to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Antofagasta to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Antofagasta to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $22 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Antofagasta to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Antofagasta to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL) cost?
Cheap round-trip fares from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL) start from $86. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Sky Airlines flight leaving ANF on August 14 2025 and touching down at SCL. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from ANF to SCL?
The cheapest flights from ANF to SCL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL)?
Avoid the layovers and fly direct to Arturo Merino Benitez Airport (SCL) from Cerro Moreno Intl. Airport (ANF) with 3 carriers, including:

  • LATAM Airlines
  • Sky Airline
  • JetSMART

What is the cheapest airline that flies from ANF to SCL?
With prices starting from $43 for a one-way journey from ANF to SCL, Sky Airlines is currently the cheapest carrier for this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from ANF on September 24 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL)?
With, on average, 17 nonstop flights that operate from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL) daily, you'll be off on your next adventure in no time.
What are the most popular departure times for flights from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL)?
More travelers fly between ANF and SCL at 8 PM than at any other time. Prefer a quieter experience? Try choosing a quieter departure window and you're likely to save on your fare as well.
What day of the week has the most flights from ANF to SCL?
Jet off on a Monday if you're after the largest selection of flights from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL).
What is the earliest flight from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL)?
Catch the earliest flight at around 6:45AM UTC-3, heading out of Cerro Moreno Intl. Airport (ANF). You'll be flying for roughly 1h 52m, reaching Arturo Merino Benitez Airport (SCL) at approximately 8:37AM UTC-3.
How long does it take to fly from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL)?
It takes around 1 hour and 52 minutes to travel the 690 mi from ANF to SCL.
What airline has the least delays from ANF to SCL?
Delta Air Lines has the best performance for on-time direct flights from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL), with an on-time rating of 95%. Use the Expedia App to check your flight status before you go and get immediate updates about any changes.
What is the best time to fly from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL)?
To arrive at Arturo Merino Benitez Airport (SCL) without delays, opt for a flight that leaves Cerro Moreno Intl. Airport (ANF) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Santiago from Cerro Moreno Intl. Airport (ANF)?
Explore your flight options from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL). This is the only airport in Santiago you can land at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL) last-minute?
Holding off until just before your trip to book your flight from ANF to SCL often results in higher prices. While you might find some last-minute offers, there's no guarantee. Allow some flexibility in your schedule to boost your chances of getting a bargain.
Is it cheaper to book an ANF to SCL flight and hotel package?
Compared with arranging flights and hotels separately, booking an ANF to SCL flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one place will take the hassle out of planning your trip. Simply pick your flights and choose from our wide range of stays, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Cerro Moreno Intl. Airport (ANF) to Arturo Merino Benitez Airport (SCL)?
If you reserved your ANF to SCL flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

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*Available to One Key members.