$373 Cheap Flights from Charleston (CHS) to Brussels (BRU)

View $373 flight on Sat, Feb 14, 2026Opens in a new window

Popular airlines from Charleston Intl. Airport (CHS) to Brussels Airport (BRU)

Cheap Flights from Charleston to Brussels (CHS-BRU)

Prices were available within the past 7 days and start at $373 for one-way flights and $457 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, Dec 8 - Tue, Dec 16
CHS
Charleston
BRU
Brussels
$457 Roundtrip, found 4 days ago
$457
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, Dec 8 from Charleston to Brussels, returning Tue, Dec 16, priced at $457 found 4 days ago
United
Tue, Feb 17 - Thu, Feb 26
CHS
Charleston
BRU
Brussels
$457 Roundtrip, found 3 days ago
$457
Roundtrip
found 3 days ago
Select United flight, departing Tue, Feb 17 from Charleston to Brussels, returning Thu, Feb 26, priced at $457 found 3 days ago
Lufthansa
Tue, Feb 17 - Thu, Feb 26
CHS
Charleston
BRU
Brussels
$457 Roundtrip, found 3 days ago
$457
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Tue, Feb 17 from Charleston to Brussels, returning Thu, Feb 26, priced at $457 found 3 days ago
Air Canada
Tue, Feb 17 - Thu, Feb 26
CHS
Charleston
BRU
Brussels
$461 Roundtrip, found 3 days ago
$461
Roundtrip
found 3 days ago
Select Air Canada flight, departing Tue, Feb 17 from Charleston to Brussels, returning Thu, Feb 26, priced at $461 found 3 days ago
United
Tue, Feb 17 - Thu, Feb 26
CHS
Charleston
BRU
Brussels
$462 Roundtrip, found 3 days ago
$462
Roundtrip
found 3 days ago
Select United flight, departing Tue, Feb 17 from Charleston to Brussels, returning Thu, Feb 26, priced at $462 found 3 days ago
Delta
Tue, Dec 9 - Tue, Dec 16
CHS
Charleston
BRU
Brussels
$462 Roundtrip, found 4 days ago
$462
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Dec 9 from Charleston to Brussels, returning Tue, Dec 16, priced at $462 found 4 days ago
Air Canada
Tue, Feb 17 - Thu, Feb 26
CHS
Charleston
BRU
Brussels
$464 Roundtrip, found 3 days ago
$464
Roundtrip
found 3 days ago
Select Air Canada flight, departing Tue, Feb 17 from Charleston to Brussels, returning Thu, Feb 26, priced at $464 found 3 days ago
United
Tue, Feb 17 - Thu, Feb 26
CHS
Charleston
BRU
Brussels
$465 Roundtrip, found 3 days ago
$465
Roundtrip
found 3 days ago
Select United flight, departing Tue, Feb 17 from Charleston to Brussels, returning Thu, Feb 26, priced at $465 found 3 days ago
American Airlines
Tue, Feb 17 - Thu, Feb 26
CHS
Charleston
BRU
Brussels
$472 Roundtrip, found 3 days ago
$472
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Feb 17 from Charleston to Brussels, returning Thu, Feb 26, priced at $472 found 3 days ago
Brussels Airlines
Mon, Jan 26 - Tue, Feb 10
CHS
Charleston
BRU
Brussels
$476 Roundtrip, found 5 days ago
$476
Roundtrip
found 5 days ago
Select Brussels Airlines flight, departing Mon, Jan 26 from Charleston to Brussels, returning Tue, Feb 10, priced at $476 found 5 days ago

Alternative airports near Brussels

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Brussels - National BRU. Cheapest and Closest option available. Average driving time to city center is 15 minutes. Flights from $1,526
BRU
Brussels - National
CheapestClosest
Average driving time to city center15 min
Flights from $1,526
Flights from Charleston (CHS) to Brussels (BRU)
Origin airport
Charleston Intl.
Destination airport
Brussels - National
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, Austrian Airlines, British Airways, Brussels Airlines, Delta, JetBlue Airways, KLM, Lufthansa, Scandinavian Airlines, TAP Portugal, Turkish Airlines, United
Roundtrip price
$457
Distance
4272 mi

Charleston to Brussels Flights

The cheapest times to fly from Charleston to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to Brussels are during the month of December. You can find some of the cheapest flights from Charleston to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charleston to Brussels

Sunday is one of the best days to book for cheap flights from Charleston to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charleston to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to Brussels in 2026. You can also book with separate airlines for your outbound and return journeys, from $373 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charleston to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Charleston Intl. Airport (CHS) to Brussels - National Airport (BRU) cost?
Lock in a cheap one-way flight from $373 or cheap return flight from $457 from Charleston Intl. Airport (CHS) to Brussels - National Airport (BRU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Charleston Intl. Airport (CHS) to Brussels - National Airport (BRU)?
December is the most affordable month to fly from CHS to BRU. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Charleston Intl. Airport (CHS) to Brussels - National Airport (BRU)?
To find the cheapest airline flying from CHS to BRU, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Charleston Intl. Airport (CHS) to Brussels - National Airport (BRU)?
There are no daily nonstop flights departing from Charleston Intl. Airport (CHS) to Brussels - National Airport (BRU). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from CHS to BRU?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charleston Intl. Airport (CHS) to Brussels - National Airport (BRU)?
To land at Brussels - National Airport (BRU) on schedule, book a flight that leaves Charleston Intl. Airport (CHS) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charleston Intl. Airport (CHS) to Brussels - National Airport (BRU) last-minute?
Last-minute fares from CHS to BRU are generally more expensive. To secure the lowest rates, start looking for flights well in advance. That being said, if you're flexible with your travel dates, it's possible to score a cheap fare right before your trip.
Is it cheaper to book a CHS to BRU flight and hotel package?
Opting for a CHS to BRU flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Choose from our impressive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Charleston Intl. Airport (CHS) to Brussels - National Airport (BRU)?
If you reserved your CHS to BRU flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more details.

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*Available to One Key members.