
Popular airlines from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW)
- American Airlines
American Airlines
- Delta
Delta
- United
United
- Spirit Airlines
Spirit Airlines
- Plan, book, fly with confidence
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Cheap Flights from Charlotte to Key West (CLT-EYW)
Prices were available within the past 7 days and start at $123 for one-way flights and $245 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Find the cheapest month to fly from Charlotte (CLT) to Key West (EYW)
February is typically the cheapest month to fly
Graph displaying average flight prices per month
Alternative airports near Key West
Prices were available within the past 7 days. Prices and availability are subject to change.
Origin airport | Charlotte-Douglas Intl. |
Destination airport | Key West Intl. |
Airlines serving | American Airlines, Delta, Spirit Airlines, United |
Roundtrip price | $245 |
Distance | 738 mi |
Average flight time | 2 hours 19 mins |
Charlotte to Key West Flights
The cheapest times to fly from Charlotte to Key West
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charlotte to Key West are during the month of November. You can find some of the cheapest flights from Charlotte to Key West with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Charlotte to Key West
Sunday is one of the best days to book for cheap flights from Charlotte to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Charlotte to Key West
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charlotte to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $123 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charlotte to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Charlotte to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
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Top Routes from Charlotte
- Charlotte to Chicago (CLT - ORD)
- Charlotte to Newark Liberty Intl. Airport (CLT - EWR)
- Charlotte to Los Angeles (CLT - LAX)
- Charlotte to Miami (CLT - MIA)
- Charlotte to Punta Cana (CLT - PUJ)
- Charlotte to Tampa (CLT - TPA)
- Charlotte to New York (CLT - LGA)
- Charlotte to Fort Lauderdale (CLT - FLL)
- Charlotte to Boston (CLT - BOS)
- Charlotte to Denver (CLT - DEN)
- Charlotte to New York (CLT - JFK)
- Charlotte to Houston (CLT - IAH)
Top Routes to Key West
- Chicago to Key West (ORD - EYW)
- Newark Liberty Intl. Airport to Key West (EWR - EYW)
- Raleigh to Key West (RDU - EYW)
- Washington to Key West (DCA - EYW)
- Tampa to Key West (TPA - EYW)
- Detroit to Key West (DTW - EYW)
- Boston to Key West (BOS - EYW)
- New York to Key West (LGA - EYW)
- Fort Lauderdale to Key West (FLL - EYW)
- Minneapolis to Key West (MSP - EYW)
- Washington to Key West (IAD - EYW)
- New York to Key West (JFK - EYW)
Top Routes from Charlotte
- Spirit Airlines Charlotte to Chicago
- Spirit Airlines Charlotte to Newark Liberty Intl. Airport
- American Airlines Charlotte to Punta Cana
- Spirit Airlines Charlotte to Tampa
- Spirit Airlines Charlotte to Fort Lauderdale
- Spirit Airlines Charlotte to Boston
- Frontier Airlines Charlotte to Denver
- American Airlines Charlotte to New York
- Spirit Airlines Charlotte to Houston
- Spirit Airlines Charlotte to New Orleans
Top Routes to Key West
- American Airlines Chicago to Key West
- American Airlines Newark Liberty Intl. Airport to Key West
- American Airlines Raleigh to Key West
- American Airlines Washington to Key West
- American Airlines Detroit to Key West
- American Airlines Boston to Key West
- American Airlines New York to Key West
- Delta Fort Lauderdale to Key West
- American Airlines Minneapolis to Key West
- Delta Washington to Key West
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Nearby Airports
- Concord Regional Airport (USA)
- Smith Reynolds Airport (INT)
- Greenville-Spartanburg Intl. Airport (GSP)
- Piedmont Triad Intl. Airport (GSO)
- Columbia Metropolitan Airport (CAE)
- Asheville Regional Airport (AVL)
- Florence Regional Airport (FLO)
- Fayetteville Regional Airport (FAY)
- Virginia Highlands Airport (VJI)
- Tri-Cities Regional Airport (TRI)
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