$255 Cheap Flights from Columbia (COU) to Key West (EYW)

Popular airlines from Columbia, MO (COU-Columbia Regional) to Key West Intl. Airport (EYW)

Cheap Flights from Columbia to Key West (COU-EYW)

Prices were available within the past 7 days and start at $255 for one-way flights and $441 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
United
Flights from Columbia (COU) to Key West (EYW)
Origin airport
Columbia Regional
Destination airport
Key West Intl.
Airlines serving
American Airlines, United
Roundtrip price
$440
Distance
1159 mi

Columbia to Key West Flights

The cheapest times to fly from Columbia to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbia to Key West are during the month of October. You can find some of the cheapest flights from Columbia to Key West with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbia to Key West

Sunday is one of the best days to book for cheap flights from Columbia to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbia to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbia to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $255 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbia to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbia to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Columbia Regional Airport (COU) to Key West Intl. Airport (EYW) cost?
Grab a cheap one-way flight from $255 or cheap return flight from $441 from Columbia Regional Airport (COU) to Key West Intl. Airport (EYW) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Columbia Regional Airport (COU) to Key West Intl. Airport (EYW)?
Traveling in October can help you save, as it's the cheapest month for flights between COU and EYW. You'll usually find the lowest prices during off-peak months.
What is the cheapest airline that flies from Columbia Regional Airport (COU) to Key West Intl. Airport (EYW)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest COU to EYW flight.
How many flights per day from Columbia Regional Airport (COU) to Key West Intl. Airport (EYW)?
Nonstop flights from Columbia Regional Airport (COU) to Key West Intl. Airport (EYW) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from COU to EYW?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Columbia Regional Airport (COU) to Key West Intl. Airport (EYW)?
To avoid possible delays on the Columbia Regional Airport (COU) to Key West Intl. Airport (EYW) route, aim to travel before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Columbia Regional Airport (COU) to Key West Intl. Airport (EYW) last-minute?
Last-minute bookings from COU to EYW are typically more expensive. To secure the best rates, start searching for flights well in advance. That said, if you're flexible with your travel dates, it's possible to score a cheap fare right before you leave.
Is it cheaper to book a COU to EYW flight and hotel package?
Compared with arranging flights and hotels separately, booking a COU to EYW flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one easy place will take the hassle out of planning your trip. Just pick your flights and choose from our wide range of stays, then customize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Columbia Regional Airport (COU) to Key West Intl. Airport (EYW)?
You can usually cancel or reschedule your COU to EYW flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.