$413 Cheap Flights from Des Moines (DSM) to Hyannis (HYA)

View $413 flight on Tue, Nov 18, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Hyannis, MA (HYA-Barnstable Municipal)

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Cheap Flights from Des Moines to Hyannis (DSM-HYA)

Prices were available within the past 7 days and start at $413 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Flights from Des Moines (DSM) to Hyannis (HYA)
Origin airport
Des Moines Intl.
Destination airport
Barnstable Municipal
Distance
1203 mi

Des Moines to Hyannis Flights

The cheapest times to fly from Des Moines to Hyannis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Hyannis are during the month of . You can find some of the cheapest flights from Des Moines to Hyannis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Hyannis

Sunday is one of the best days to book for cheap flights from Des Moines to Hyannis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Hyannis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Hyannis in 2025. You can also book with separate airlines for your outbound and return journeys, from $413 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Hyannis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Hyannis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Barnstable Municipal Airport (HYA) cost?
Lock in a cheap one-way flight from $413 or cheap return flight from Des Moines Intl. Airport (DSM) to Barnstable Municipal Airport (HYA) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Barnstable Municipal Airport (HYA)?
The cheapest month to fly from DSM to HYA is , when there's less demand. Off-peak season is generally when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Barnstable Municipal Airport (HYA)?
To find the cheapest airline that'll fly you from DSM to HYA, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Des Moines Intl. Airport (DSM) to Barnstable Municipal Airport (HYA)?
You'll have to catch a flight with a layover if you're traveling from Des Moines Intl. Airport (DSM) to Barnstable Municipal Airport (HYA). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from DSM to HYA?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can change based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Barnstable Municipal Airport (HYA)?
To avoid possible delays on the Des Moines Intl. Airport (DSM) to Barnstable Municipal Airport (HYA) route, travel before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Barnstable Municipal Airport (HYA) last-minute?
Booking your flight from DSM to HYA right before your journey is typically more expensive. But if there's some wiggle room with your schedule, you could snag a cheap last-minute fare.
Is it cheaper to book a DSM to HYA flight and hotel package?
Opting for a DSM to HYA flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Choose from our wide range of accommodations and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Barnstable Municipal Airport (HYA)?
If you booked your DSM to HYA flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

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