$135 Cheap Flights from Panama City (ECP) to Buffalo (BUF)

View $135 flight on Tue, Jan 20, 2026Opens in a new window

Popular airlines from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Panama City to Buffalo (ECP-BUF)

Prices were available within the past 7 days and start at $135 for one-way flights and $269 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Dec 25 - Sat, Jan 17
ECP
Panama City
BUF
Buffalo
$269 Roundtrip, found 3 days ago
$269
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Dec 25 from Panama City to Buffalo, returning Sat, Jan 17, priced at $269 found 3 days ago
Delta
Thu, Dec 25 - Tue, Jan 13
ECP
Panama City
BUF
Buffalo
$291 Roundtrip, found 3 days ago
$291
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Dec 25 from Panama City to Buffalo, returning Tue, Jan 13, priced at $291 found 3 days ago
American Airlines
Fri, Feb 6 - Wed, Feb 18
ECP
Panama City
BUF
Buffalo
$294 Roundtrip, found 3 days ago
$294
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Feb 6 from Panama City to Buffalo, returning Wed, Feb 18, priced at $294 found 3 days ago
Delta
Wed, Dec 24 - Wed, Jan 7
ECP
Panama City
BUF
Buffalo
$296 Roundtrip, found 3 days ago
$296
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Dec 24 from Panama City to Buffalo, returning Wed, Jan 7, priced at $296 found 3 days ago
American Airlines
Fri, Feb 6 - Wed, Feb 18
ECP
Panama City
BUF
Buffalo
$299 Roundtrip, found 3 days ago
$299
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Feb 6 from Panama City to Buffalo, returning Wed, Feb 18, priced at $299 found 3 days ago
Delta
Thu, Dec 25 - Sun, Jan 11
ECP
Panama City
BUF
Buffalo
$302 Roundtrip, found 3 days ago
$302
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Dec 25 from Panama City to Buffalo, returning Sun, Jan 11, priced at $302 found 3 days ago
Delta
Wed, Dec 24 - Sun, Jan 11
ECP
Panama City
BUF
Buffalo
$307 Roundtrip, found 3 days ago
$307
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Dec 24 from Panama City to Buffalo, returning Sun, Jan 11, priced at $307 found 3 days ago
Delta
Thu, Dec 25 - Thu, Jan 8
ECP
Panama City
BUF
Buffalo
$310 Roundtrip, found 3 days ago
$310
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Dec 25 from Panama City to Buffalo, returning Thu, Jan 8, priced at $310 found 3 days ago
Southwest Airlines
Thu, Feb 5 - Tue, Feb 10
ECP
Panama City
BUF
Buffalo
$330 Roundtrip, found 12 hours ago
$330
Roundtrip
found 12 hours ago
Select Southwest Airlines flight, departing Thu, Feb 5 from Panama City to Buffalo, returning Tue, Feb 10, priced at $330 found 12 hours ago
United
Wed, Dec 24 - Thu, Jan 1
ECP
Panama City
BUF
Buffalo
$339 Roundtrip, found 6 days ago
$339
Roundtrip
found 6 days ago
Select United flight, departing Wed, Dec 24 from Panama City to Buffalo, returning Thu, Jan 1, priced at $339 found 6 days ago

Find the cheapest month to fly from Panama City (ECP) to Buffalo (BUF)

October is typically the cheapest month to fly

From $208 - $676 per traveler.

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Buffalo Niagara Intl. BUF. Cheapest and Closest option available. Average driving time to city center is 16 minutes. Flights from $368
BUF
Buffalo Niagara Intl.
CheapestClosest
Average driving time to city center16 min
Flights from $368

Frequently asked questions

How much does a flight from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF) cost?
Grab a cheap one-way flight from $135 or cheap return flight from $269 from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF)?
December is the most affordable month to fly from ECP to BUF. Traveling during an off-peak travel window is often the key to finding better fares.
What is the cheapest airline that flies from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from ECP to BUF. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF)?
You'll need to book a flight with a layover if you're traveling from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from ECP to BUF?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary depending on various factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF)?
Choose a flight from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF) last-minute?
Holding off until right before your break to book a flight from ECP to BUF generally means paying more. Although you may find some last-minute offers, they're not always guaranteed. Allow some flexibility in your schedule for the best chance of getting a bargain.
Is it cheaper to book an ECP to BUF flight and hotel package?
Compared with arranging hotels and flights separately, booking an ECP to BUF flight and hotel package with Expedia could lead to significant savings. Better still, managing everything in one place will take the hassle out of travel planning. Just pick your flights and select from our extensive range of hotels, then personalize your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from Northwest Florida Beaches Intl. Airport (ECP) to Buffalo Niagara Intl. Airport (BUF)?
If you reserved your ECP to BUF flight within the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Northwest Florida Beaches Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$268
Distance
952 mi

Book with confidence

Panama City to Buffalo Flights

The cheapest times to fly from Panama City to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Buffalo are during the month of December. You can find some of the cheapest flights from Panama City to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Buffalo

Sunday is one of the best days to book for cheap flights from Panama City to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $135 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Buffalo Flights

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*Available to One Key members.