$454 Cheap Flights from Istanbul (IST) to Buffalo (BUF)

View $454 flight on Mon, Mar 16, 2026Opens in a new window

Popular airlines from Istanbul Airport (IST) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Istanbul to Buffalo (IST-BUF)

Prices were available within the past 7 days and start at $454 for one-way flights and $766 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sat, Nov 15 - Tue, Nov 18
IST
Istanbul
BUF
Buffalo
$766 Roundtrip, found 6 days ago
$766
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Nov 15 from Istanbul to Buffalo, returning Tue, Nov 18, priced at $766 found 6 days ago
Delta
Wed, Feb 18 - Tue, Mar 24
IST
Istanbul
BUF
Buffalo
$780 Roundtrip, found 1 day ago
$780
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Feb 18 from Istanbul to Buffalo, returning Tue, Mar 24, priced at $780 found 1 day ago
KLM
Fri, Jan 16 - Fri, Feb 20
IST
Istanbul
BUF
Buffalo
$785 Roundtrip, found 6 days ago
$785
Roundtrip
found 6 days ago
Select KLM flight, departing Fri, Jan 16 from Istanbul to Buffalo, returning Fri, Feb 20, priced at $785 found 6 days ago
KLM
Fri, Jan 16 - Fri, Feb 20
IST
Istanbul
BUF
Buffalo
$791 Roundtrip, found 6 days ago
$791
Roundtrip
found 6 days ago
Select KLM flight, departing Fri, Jan 16 from Istanbul to Buffalo, returning Fri, Feb 20, priced at $791 found 6 days ago
KLM
Fri, Jan 16 - Fri, Feb 20
IST
Istanbul
BUF
Buffalo
$791 Roundtrip, found 6 days ago
$791
Roundtrip
found 6 days ago
Select KLM flight, departing Fri, Jan 16 from Istanbul to Buffalo, returning Fri, Feb 20, priced at $791 found 6 days ago
Air France
Thu, Mar 26 - Mon, Apr 6
IST
Istanbul
BUF
Buffalo
$795 Roundtrip, found 1 day ago
$795
Roundtrip
found 1 day ago
Select Air France flight, departing Thu, Mar 26 from Istanbul to Buffalo, returning Mon, Apr 6, priced at $795 found 1 day ago
KLM
Fri, Apr 3 - Mon, Apr 13
IST
Istanbul
BUF
Buffalo
$796 Roundtrip, found 1 day ago
$796
Roundtrip
found 1 day ago
Select KLM flight, departing Fri, Apr 3 from Istanbul to Buffalo, returning Mon, Apr 13, priced at $796 found 1 day ago
Delta
Fri, Jan 23 - Fri, Feb 27
IST
Istanbul
BUF
Buffalo
$800 Roundtrip, found 6 days ago
$800
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Jan 23 from Istanbul to Buffalo, returning Fri, Feb 27, priced at $800 found 6 days ago
United
Tue, Nov 18 - Mon, Nov 24
IST
Istanbul
BUF
Buffalo
$816 Roundtrip, found 6 days ago
$816
Roundtrip
found 6 days ago
Select United flight, departing Tue, Nov 18 from Istanbul to Buffalo, returning Mon, Nov 24, priced at $816 found 6 days ago
American Airlines
Fri, Jan 23 - Fri, Feb 27
IST
Istanbul
BUF
Buffalo
$818 Roundtrip, found 6 days ago
$818
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jan 23 from Istanbul to Buffalo, returning Fri, Feb 27, priced at $818 found 6 days ago

Frequently asked questions

How much does a flight from Istanbul (IST) to Buffalo Niagara Intl. Airport (BUF) cost?
Snag a cheap one-way flight from $454 or cheap return flight from $766 from Istanbul (IST) to Buffalo Niagara Intl. Airport (BUF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Istanbul (IST) to Buffalo Niagara Intl. Airport (BUF)?
November is the least expensive month to fly from IST to BUF. Planning your trip for the off-season is often the key to finding better fares.
What is the cheapest airline that flies from Istanbul (IST) to Buffalo Niagara Intl. Airport (BUF)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest IST to BUF flight.
How many flights per day from Istanbul (IST) to Buffalo Niagara Intl. Airport (BUF)?
You'll have to book a flight with a layover if you're traveling from Istanbul (IST) to Buffalo Niagara Intl. Airport (BUF). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from IST to BUF?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change based on various factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Istanbul (IST) to Buffalo Niagara Intl. Airport (BUF)?
To reach Buffalo Niagara Intl. Airport (BUF) without delays, pick a flight that leaves Istanbul (IST) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Istanbul (IST) to Buffalo Niagara Intl. Airport (BUF) last-minute?
Waiting until just before your departure to book a flight from IST to BUF often results in higher prices. While you might find some last-minute deals, they're not always guaranteed. Be flexible with your itinerary to maximize your chances of getting a bargain.
Is it cheaper to book an IST to BUF flight and hotel package?
You'll typically save money by booking an IST to BUF flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. After selecting your ideal accommodations and flights, consider other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Istanbul (IST) to Buffalo Niagara Intl. Airport (BUF)?
You can usually cancel or reschedule your IST to BUF flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Istanbul
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, British Airways, Delta, KLM, Lufthansa, Turkish Airlines, United
Roundtrip price
$766
Distance
5078 mi

Book with confidence

Istanbul to Buffalo Flights

The cheapest times to fly from Istanbul to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Istanbul to Buffalo are during the month of November. You can find some of the cheapest flights from Istanbul to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Istanbul to Buffalo

Sunday is one of the best days to book for cheap flights from Istanbul to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Istanbul to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Istanbul to Buffalo in 2025. You can also book with separate airlines for your outbound and return journeys, from $454 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Istanbul to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Istanbul to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Istanbul to Buffalo Flights

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*Available to One Key members.